@samuelfoley.com on bsky || Biophysics Postdoc at Johns Hopkins @JenkinsBiophys || I don't use this platform anymore, find me on bluesky
Joined July 2009
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294 Photos and videos
26 May 2025
I’m excited to finally share our new preprint! Membrane-associated assembly processes like CME function as precisely-tunable, spatially targetable, robust on/off switches that don’t require energy at decision-time.
#biophysics
arxiv.org/abs/2505.17290
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26 May 2025
The real kicker, though: In order for this switching mechanism to be robust and functional, the component concentrations and affinities need to be tuned into fairly precise ranges. We find that evolution has done exactly that for the components of the endocytic machinery!
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26 May 2025
As a final note, we point out the advantages of membrane binding and self-assembly over simpler passive mechanisms, chief among them being precise thresholding and magnitude of response.
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10 Nov 2024
same username on bsky
7 Nov 2024
I think it's past time I uninstalled this app
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Sam Foley retweeted
6 Nov 2024
MIssouri voters voting for abortion rights, an increase in the minimum wage, and paid sick leave, and a senator and a president who strongly oppose these things is where we are in a nutshell
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6 Nov 2024
Are we ready to talk about the election models being worse than in 2016?
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5 Nov 2024
Vote cast, all I gotta do now is wait. That's the easy part, right?
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5 Nov 2024
This template can also be recycled by swapping out "Vote cast" for "Grant application submitted"
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4 Nov 2024
It is so strange to see Trump campaigning in the tiny city I grew up outside of multiple times in the month before the election
4 Nov 2024
Pennsylvania the day before the Election:
2 pm - Trump, Reading
4 pm - Harris, Allentown
6 pm - Trump, Pittsburgh
8:30 pm - Harris, Pittsburgh
8:30 pm - Vance, Newtown
11 p.m. - Harris, Philly
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4 Nov 2024
Anyone in my Twitter sphere going to the Mid Atlantic Soft Matter Workshop at U Delaware later this month?
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4 Nov 2024
And a reminder to everyone using scipy's curve_fit routine, you must pass absolute_sigma=True to get a legitimate parameter covariance matrix out
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1 Nov 2024
What the hell
George Lucas cut a bombshell reveal from "Star Wars: The Phantom Menace": Liam Neeson was originally Obi-Wan Kenobi, and thus the real Obi-Wan died.
"For a time, the older Jedi was named Obi-Wan and the younger Jedi was named Qui-Gon. It was very poignant that at the end, as Obi-Wan dies and Qui-Gon defeats Darth Maul and stays with his Master as he passes away, he not only takes on his Master’s quest but he takes on his name. Qui-Gon becomes Obi-Wan. That’s why when you see Alec Guinness in ‘A New Hope,’ he puts his hood down and goes, ‘Obi-Wan? Now that’s a name I’ve not heard…' Because he’s not Obi-Wan, he’s Qui-Gon. And right at the end, George changed it.”
Read more here: variety.com/2024/film/news/g…
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30 Oct 2024
Okay I've encountered one weird but harmless side effect... matplotlib run through PythonCall.jl (on the left) flips my cursor to a left-handed version in interactive mode somehow?? (proper python version on the right)
29 Oct 2024
doing
plt = pyimport("matplotlib.pyplot")
in Julia and then acting like I'm just using regular matplotlib in python feels like a crime against nature but... it's actually kinda nice?
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