How do you "control" for a surgical intervention that enforces sexual abstinence for weeks?
Proxy consent is not valid for a cosmetic procedure!
You don't need RCTs, just compare the US to any other developed nation that doesn't amputate parts of little boys!
You're aware that the original HIV trial was ended early due to ethical concerns of NOT publishing immediately, right? That the study team felt that they could not in good conscience randomize African men to a control group based on the results they saw?
More RCTs would absolutely be welcome, but the number of parents who don't already have strong feelings one way or another on circumcision such that they would enroll their infant boys would make enrolling enough in a cohort of 48-hour-old American boys challenging.