Paediatric oncologist, clinical trials, neuro-oncology, precision medicine.

Joined December 2019
20 Photos and videos
Prof David Ziegler retweeted
Thanks to The @australian for highlighting this research theaustralian.com.au/health/…

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Prof David Ziegler retweeted
Excited to share our latest publication - precision medicine is the right approach for DMG / DIPG! nature.com/articles/s41467-0…

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Excited to share our latest publication - precision medicine is the right approach for DMG / DIPG! nature.com/articles/s41467-0…

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Thanks to The @australian for highlighting this research theaustralian.com.au/health/…

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Prof David Ziegler retweeted
Heading to the #AACR26 Education Session "Small Patients, Big Data: Making Precision Medicine Work in Pediatric Cancer"? Take a look at this study coauthored by speaker David Ziegler. brnw.ch/21x1IAH @ProfDavidZieg
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And now actually published in open access :) !! rdcu.be/fa3nt

Delighted to share our manuscript - the first look at the epi-transcriptome in DMG! We discovered that RNA methylation is a critical regulator in DMG. nature.com/articles/s41419-0…
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Our lab just published a JoVE video article covering PDX models for paediatric brain cancer. Here’s a quick preview! Link to full video and article: hubs.ly/Q042_QJ40
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Prof David Ziegler retweeted
📰 Discover the special issue of #Daily27 for #ChildhoodCancerDay Read insights from international experts in our two new articles on #childhoodcancerawareness and new advances in the fight against pediatric brain tumors 💛 #EndChildhoodCancer #Oncology #Health #News 👇🧵
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Thanks to 27 Daily for allowing me to share some thoughts on World Childhood Cancer Day
Replying to @Daily27Info
🧵'A New Chapter in the Fight Against Childhood Brain Cancer' 🌍 #InternationalChildhoodCancerDay ✍️ David Ziegler, paediatric oncologist at the @KidsCancerInst 🔗 daily27.info/2026/02/15/a-ne… #EndChildhoodCancer #BrainCancer #Health #News
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Very excited about this paper - new way to shut down transcription in DMG - looking now at clinical translation
Inhibitors of the proteins FACT and BET disrupt transcription in #DiffuseMidlineGlioma and extend survival in mice, hinting this combo can suppress hard-to-target epigenetic drivers of this pediatric cancer. @holly_holliday_ @ProfDavidZieg @KidsCancerInst scim.ag/3ZfoysL
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Prof David Ziegler retweeted
Congrats to the team for our work - on the cover of Science Translational Medicine! One more step forward to find effective treatments for #DIPG. Thanks to all our funders - See details here:
New in @ScienceTM 🧬 On the cover! Our work on diffuse midline glioma (#DMG #DIPG), an incurable paediatric brain cancer driven by epigenetic changes. We asked: Can targeting chromatin slow tumour growth?🔗science.org/doi/10.1126/scit… #ScienceTranslationalMedicineResearch
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Prof David Ziegler retweeted
New in @ScienceTM 🧬 On the cover! Our work on diffuse midline glioma (#DMG #DIPG), an incurable paediatric brain cancer driven by epigenetic changes. We asked: Can targeting chromatin slow tumour growth?🔗science.org/doi/10.1126/scit… #ScienceTranslationalMedicineResearch
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Prof David Ziegler retweeted
Together, these results support dual FACT BET inhibition as a promising DMG therapy, hitting both tumour-intrinsic vulnerabilities and immune defenses. @KidsCancerInst @UNSW Huge thanks to @aaminahkhan_1, @ProfDavidZieg, @maria_tsoli & all collaborators!
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Prof David Ziegler retweeted
This work was generously supported by grants from @nhmrc, @cancerNSW, @DIPGCollab, @CureStartsNowAU, @KidsCancerProj, @thekca, We Love You Connie Foundation and Levi’s project
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Prof David Ziegler retweeted
5 Dec 2025
Listen to Oprah! Time to book your trip to Australia. #ISPNO2026 instagram.com/reel/DRw5SJ1gG…
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Prof David Ziegler retweeted
17 Nov 2025
Registration and abstract submissions now open for ISPNO 2026! ispno2026.org The world's entire paediatric brain tumour community will be heading Down Under in 2026 - don't miss out!
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Prof David Ziegler retweeted
17 Oct 2025
Join us in Sydney for ISPNO 2026! Experience one of the world’s most vibrant cities, where golden beaches, iconic landmarks & rich First Nations culture await. 🌊🌿 📍 Watch: vimeo.com/1126715713 Registrations open: ispno2026.org #ISPNO2026 #Sydney #SeeAustralia
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You might even get a free koala 🐨
12 May 2025
ISPNO 2026 now just over a year away! We will be attending PedSNO - come visit for a chance at complimentary registration!!
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