Synthetic and medicinal chemistry at UT Southwestern Medical Center

Joined August 2022
1 Photos and videos
24 Jan 2025
very cool paper from our former co-worker Lingying Leng: Discovery of High-Affinity SMARCA2/4 Bromodomain Ligands and Development of Potent and Exceptionally Selective SMARCA2 PROTAC Degraders | Journal of Medicinal Chemistry
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4 Nov 2024
Congrats to Jue on her ACS Med Chem Lett paper: Bicyclic Inhibitors of Branched-Chain α-Keto Acid Dehydrogenase Kinase (BDK) with In Vivo Activity | ACS Medicinal Chemistry Letters
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30 Jul 2024
Suraksha's Cell Chem Bio paper on malaria proteasome inhibitors: doi.org/10.1016/j.chembiol.2…

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30 Jul 2024
Great paper from Suraksha on our collaboration with the Phillips lab targeting the malaria proteasome: Identification of potent and reversible piperidine carboxamides that are species-selective orally active proteasome inhibitors to treat malaria - ScienceDirect
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20 Sep 2023
Cool paper on Zweifel olefination from our friends at IIT Kharagpur: onlinelibrary.wiley.com/doi/…

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18 Sep 2023
Congrats to Suraksha and Yesu for a cool asymmetric route to sulfoxides: Enzymatic Resolution and Decarboxylative Functionalization of α‐Sulfinyl Esters - Gahalawat - Chemistry – A European Journal - Wiley Online Library
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26 Jul 2023
Dmitry's paper on asymmetric hydroboration of enol carbamates is out. Timing was great because this is the 60th anniversary of the Matteson Reaction, and Dmitry's chemistry fits right into that pathway. thieme-connect.de/products/e…

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9 Jun 2023
Congrats to James Mcgettigan. He was nominated as the student speaker in the Aldrich symposium. Great talks by Joe Fox (@FoxGroupUD) and Christina Woo
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2 Mar 2023
Congrats to Xioafeng Liu, former postdoc with us at UTSW. He's one of the inventors of the new Reata drug Omavaloxolone: patents.google.com/patent/US…

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