Toronto-based ImmVue Therapeutics Inc. has licensed a potential @UMassChan cancer therapeutic for clinical development: direc.to/m4zF
This partnership was facilitated by BRIDGE Innovation and Business Development at UMass Chan. @immvue@CUMedicalSchool
In @JExpMed, @ReboldiLab@BucciVanni et al. reveal that #microbiome-driven tuft cellsโ hyperplasia in the colon helps defend against Clostridioides difficile infection, providing a pathway thru which host & microbial interactions protect against pathogens hubs.la/Q02ZBWxx0
Looking to learn more about modulation of the immune response in tissue by cholesterol & cholesterol metabolites? ๐๐๐๐ง
Check out the review @EricVDang1 and I wrote for @TrendsImmunosciencedirect.com/science/arโฆ
Weโd like to extend a huge congratulations to the newly minted Dr. Fiona Raso!!! The first PhD student of the lab to graduate. She has worked extremely hard throughout the years and her success is well-deserved! Cheers to you and your bright future as a scientist ๐ฅ
UMass Chan Medical School researcher Victor R. Ambros, PhD, shares the 2024 @NobelPrize in Physiology or Medicine for his co-discovery of microRNA, single-stranded RNA molecules that play a critical role in post-transcriptional gene regulation: direc.to/mmJ6#NobelPrize
ALT Congratulations to Nobel Prize winner Victor Ambros, PhD
Microbiota encoded fatty-acid metabolism expands tuft cells to protect tissues homeostasis during Clostridioides difficile infection in the large intestine biorxiv.org/content/10.1101/โฆ new preprint from the lab. Finalizing experiments for full paper reviews.. @ReboldiLab
Katalin Karikรณ and Drew Weissman โ awarded the 2023 #NobelPrize in Physiology or Medicine โ discovered that base-modified mRNA can be used to block activation of inflammatory reactions and increase protein production when mRNA is delivered to cells.
Scientists led by Dr. Andrea Reboldi (@ReboldiLab) at @UMassChan have shown that antigen receptor signaling and cell death resistance control intestinal humoral response zonation.
๐ Study: bit.ly/48wDje6
๐ง Episode: bit.ly/3Pzas05
Moreover, IgA BCR is inherently required for the acquisition of gut-homing receptors by plasma cells, a process that is independent of Fas-FasL axis. (5/6)