We’re excited to present our most recent preprint on bioRxiv “Multimodal single-cell profiling of T cell specificity and reactivity in lung cancer ” biorxiv.org/content/10.1101/…
We’re excited to present our most recent preprint on bioRxiv “Multimodal single-cell profiling of T cell specificity and reactivity in lung cancer ” biorxiv.org/content/10.1101/…
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With tumor-reactive TILs being partly in the proliferation cluster, we wondered how their cell states change upon short-term stimulation culture. This showed an increased transition from the resident memory to the proliferative cell state.
We're excited to present SpeedingCARs, our most recent paper published by @NatureComms describing an integrated method to engineer CAR T cells using signalling domain shuffling and single-cell sequencing.
nature.com/articles/s41467-0…
In summary, speedingCARs substantially expands and characterizes the signaling domain combinations suited for CAR design and supports the engineering of the next-generation T cell #immunotherapies.
ETH-Zürich (@ETH_en) has put out a great summary of our DML technique and how it can help us develop more effective antibody therapies and vaccines against future variants of SARS-CoV-2. Read more about it here: ethz.ch/en/news-and-events/e…
Now online! Deep Mutational Learning Predicts ACE2 Binding and Antibody Escape to Combinatorial Mutations in the SARS-CoV-2 Receptor Binding Domain dlvr.it/SXXV9K
It has been 2 years since the 1st detection of #SARSCoV2 and yet the #pandemic shows little signs of slowing down, as seen most recently through the emergence of #omicron and its surprisingly large No. of mutations. How surprising is that though? A thread. biorxiv.org/content/10.1101/…