Professor metabolic aspects of vascular disease I Chairman European Lipoprotein Club #brownfat #nash #circadianrhythm #atherosclerosis
Joined August 2020
- Tweets 221
- Following 867
- Followers 1,228
- Likes 1,108
26 Photos and videos
Patrick Rensen retweeted
Feb 3
Workshop Spotlight: Cholesterol- and Triglycerides-Rich Remnants
Join experts Mie Balling and Patrick Rensen to explore remnant cholesterol's impact on ASCVD and its molecular mechanisms.
🔗 Explore the workshop: bit.ly/48CEGca
#Atherosclerosis #EASCongress2026
4
10
709
Patrick Rensen retweeted
18 Mar 2025
Guoli Li, Sijing Dong, Chunhao Liu, Jing Yang, Patrick C N Rensen, Yanan Wang
academic.oup.com/lifemeta/ar…
1
1
2
287
13 Nov 2024
Great paper of the Gerhart-Hines group just appeared in @Nature! 😊👍 Happy to have been modestly involved!
13 Nov 2024
Our new paper, "NK2R control of energy expenditure and feeding to treat metabolic diseases," is out today in @Nature.
Here we identify a single receptor that can both peripherally increase energy expenditure and centrally suppress appetite.
nature.com/articles/s41586-0…
1/12 🧵👇
1
2
12
860
12 Sep 2024
Just online: Liver-targeted Angptl4 silencing attenuates hyperlipidemia and atherosclerosis development in APOE*3-Leiden.CETP mice, our well-established model for human-like lipid metabolism and cardiometabolic diseases @LUMC_Leiden @Lipigon_Pharma academic.oup.com/cardiovascr…
2
25
1,055
22 May 2024
It was a real pleasure to give a keynote on (pre)clinical studies on #brownadiposetissue #bat at the annual meeting of the Austrian Atherosclerosis Society. Thank you so much for the kind invite! @LUMC_Leiden
1
8
969
17 May 2024
Just published in ATVB. Kudos to Frank Schaftenaar!
17 May 2024
Pharmacologic inhibition of the immunoproteasome with ONX-0914 attenuates atherosclerosis, metabolic syndrome, and reduces white adipose tissue mass in mice @Rensen_Lab @FoksAmanda @mariedepuydt @JilldeMol
ahajrnls.org/4aolEW2
1
10
779
10 May 2024
51 weeks a year a devoted scientist, one week a year absolutely not 😉🎉🎈🇳🇱
9 May 2024
6
37
2,782
Patrick Rensen retweeted
9 May 2024
4
24
311
38,427
23 Apr 2024
#CETP inhibition enhances bacterial clearance to reduce pneumoniae-associated mortality in APOE*3-Leiden.CETP mice, suggesting CETP inhibitors to be repurposed to prevent #sepsis-related mortality in humans! @LUMC_Leiden
insight.jci.org/articles/vie…
8
502
1 Nov 2023
CETP Inhibition may well have therapeutic applications beyond targeting ASCVD, including protection against septicemia. Certainly relevant, giving that the bulk of circulating #CETP derives from #macrophages! @LUMC_Leiden @NewAmsPharma sciencedirect.com/science/ar…
1
5
12
1,497
1 Aug 2023
Proud of @MilenaSchonke who just received an #EFSD grant to study the molecular mechanisms by which late #exercise via the #gut #microbiome improves #NAFLD! @LUMC_Leiden
👇
1
3
32
8,024
27 Jul 2023
Proud of @KooijmanSander who was awarded a Dekker Senior Scientist grant of the Dutch Heart Foundation to dive deeper into the #circadianrhythmn of #brownfat to reveal novel (chrono)therapeutic approaches to comBAT atherosclerotic #CVD! 😊👍 #batman @LUMC_Leiden
👇
27 Jul 2023
De Hartstichting feliciteert 10 toponderzoekers van @ErasmusMC, @MaastrichtUMC, @umcg, @amsterdamumc, @LUMC_Leiden, @UMCUtrecht met de toekenning van de Dekkerbeurs. Hiermee kunnen zij belangrijk onderzoek doen naar hart- en vaatziekten.
1
1
19
1,570
20 Jul 2023
Highly recommended PhD position with a dedicated supervisor in Almería, and with the opportunity to perform part of the research at @LUMC_Leiden! 😊👍
📢We are offering a PhD position📢. Those who are interested, send me an email!
@FPUinvestiga @FJIprecarios
6
943
14 Jul 2023
Pharmacological inhibition of DHCR24 prevents #nash development by increasing the endogenous #lxr agonist #desmosterol! @LUMC_Leiden #patentpending
👇
lumc.nl/en/about-lumc/news/2…
1
2
9
1,335
28 Jun 2023
Today Huub van Eyk defended his thesis ‘GLP-1 receptor agonism to improve cardiometabolic health’, also with flying colors! Proud promotor! 😊🎉🎈 @LUMC_Leiden
17
781
Patrick Rensen retweeted
27 Jun 2023
.@LUMC_Leiden researchers and collaborators show that inhibition of DHCR24 decreases liver #collagen content and plasma alanine transaminase levels in an established #NAFLD model.
🔓 #OpenAccess at @EmboMolMed
bit.ly/46kjCW9
4
13
1,631
27 Jun 2023
Today Robin van Eenige defended his thesis ‘Targeting adipose tissue to improve cardiometabolic health’ with flying colors! All six experimental chapters, mainly supervised by @KooijmanSander have been published. Very proud promotor! 😊 @LUMC_Leiden
26
1,050
27 Jun 2023
Combined #GIP and #GLP1 receptor agonism additively attenuate #NAFLD development. Proud of Zhixiong and Robin! 😊👍 @LUMC_Leiden @EliLillyandCo
sciencedirect.com/science/ar…
9
683
26 Jun 2023
Just published: a novel pharmacological approach to block #nash development by specifically activating LXRa in macrophages. Proud of @Enchen__Zhou ! 😊👍
embopress.org/doi/full/10.15…
1
27
92
14,585
24 Jun 2023
It has been great organizing a lipid session with @PAspichueta at #EASL2023! Already looking forward to next year’s edition! 😊👍
24 Jun 2023
Novel strategies to target lipid metabolism una NASH in #EASL2023 . It was a pleasure to share the session with @RubenNogueiras @Rensen_Lab #GregorySteinberg @PAspichueta
12
1,232