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Reproduction and Fertility @Repro_Fertility

A fully open-access journal from @SRF_Repro & @Soc_Endo publishing research & reviews. IF: 3.4.

Joined March 2020
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Reproduction and Fertility is pausing activity on X. Join the conversation and stay updated with us: 🟢LinkedIn: linkedin.com/showcase/reprod… 🟢Bluesky: bsky.app/profile/repro-ferti… 🟢Instagram: instagram.com/repro_fertilit… Thank you for following us, see you over on our other channels! 💚
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Day 5 - Our #RaFJC comes to its end. We toured the reproduction path as an immune continuum. From ovulation, implantation, pregnancy outcomes, and therapies. #Pregnancyloss #IVF #Miscarriage #immuneresponse #inflammatoryresponse
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Did you know that we run a longer debate on LinkedIn? Follow Reproduction and Fertility and don't miss the updates! linkedin.com/showcase/reprod…

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Explore the Special Collection: raf.bioscientifica.com/page/… #Pregnancyloss #IVF #Miscarriage #immuneresponse #inflammatoryresponse
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#RaFJC Day 4 - RPL = ≥2 miscarriages, affecting 1–2% of couples. Half remain unexplained, often immune‑related. #RaFJC #Pregnancyloss #IVF #Miscarriage #immuneresponse #inflammatoryresponse
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New concept: placenta‑targeted nanoparticles for localized immune cloaking. Cost‑optimized, safer than systemic immunosuppression.
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Read the full article here: doi.org/10.1530/RAF-25-0077 Explore the special collection: raf.bioscientifica.com/page/… #RaFJC #Pregnancyloss #IVF #Miscarriage #immuneresponse #inflammatoryresponse

Cost-optimized placenta-targeted nanoparticle for localized immune cloaking in recurrent pregnancy...

Abstract Recurrent pregnancy loss (RPL) is defined as the occurrence of two or more consecutive miscarriages and affects approximately 1–2% of reproductive-aged couples. Immune-mediated factors at...

raf.bioscientifica.com
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#RaFJC Day 3💚 Pregnancy is an immune balancing act: tolerance of the fetus defense against pathogens.
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more replies
B cells rise in all pregnancies, but only pNK signatures distinguish viable vs non‑viable outcomes
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Immune profiling in patients with positive hCG could become an early diagnostic tool. 👉 Read the full article: doi.org/10.1530/RAF-24-0034 Explore the special collection: raf.bioscientifica.com/page/…

Comparing surface immune markers in successful and non-viable ART pregnancies on the day of hCG...

Abstract Blood lymphocyte reference ranges in non-pregnant females are established, but changes in pregnancy are less well understood. The early identification of immunological markers that could...

raf.bioscientifica.com
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𝗗𝗮𝘆 𝟮 𝗼𝗳 #RaFJC 💚 Implantation requires delicate immune balance. Enough inflammation to remodel the uterus, but enough tolerance to accept the embryo. Cytokines, NK cells, and macrophages shape embryo acceptance. #RaFJC #Implantation #Fertility #immuneresponse
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Implantation depends on a fine balance of the immune system. When tolerance and inflammation fall out of sync, the risks rise — from failed implantation to recurrent miscarriage and pregnancy complications. #RaFJC #Implantation #Fertility #immuneresponse #inflammatoryresponse

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Are you interested in this topic? Explore our next Special Collection : Immune Regulation and Inflammatory Mechanisms in Reproductive Health and Disease, and submit your article to be a part of it! raf.bioscientifica.com/page/…

Immune Regulation and Inflammatory Mechanisms in Reproductive Health and Disease

raf.bioscientifica.com
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👱‍♀️POI affects 1–3% of women <40; most cases are unexplained.
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🐁A mouse model shows cathepsin K triggers rapid ovarian transcript changes
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Immune extracellular membrane pathways emerge as key players! Read the full article here: doi.org/10.1530/RAF-22-0036 #RaFJC #Ovulation #POI #Fertility
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We’re excited to announce our next Journal Club! Hosted on all RAF social platforms, this week-long event will feature discussions on 3 articles, covering the journey from ovulation to conception & implantation, through pregnancy & delivery, & clinical translation. #RaFJC
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New research by Meron Asmamaw Alemayehu et al. finds machine learning models can help identify factors linked to delayed fecundability among women in sub-Saharan Africa - paving the way for more targeted fertility support. 🔗Read the full article here: doi.org/10.1530/RAF-25-0068
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Did you know Reproduction & Fertility is co-owned by both the Society for Endocrinology & the Society for Reproduction & Fertility? Members of either society get 25% off APCs when publishing with us! For more info visit: raf.bioscientifica.com/page/…
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