Spotlighting the founders & builders pushing the frontiers of AI innovation
Joined November 2025
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DeepMind's AlphaGo didn't learn how to win by watching humans play. It played itself and discovered strategies no human had ever considered.
Recently, the same logic has been applied to drug discovery. 1/6
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“AI gives us better insights earlier in the process,” said @bmabey, CTO at @RecursionPharma. The company developed a cancer drug in half the usual time, thanks to AI. @InSilicoMeds was first to clear Phase 2 with an AI-discovered drug. 5/6
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Dozens of AI-designed candidates are currently in Phase 2 and Phase 3 trials. With the first results coming out this year, new AI drugs could be hitting the market soon.
@thomas_macaulay explores new approaches to drug discovery: infiniteloop.media/p/ai-drug…
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How does Silicon Valley prepare to kick off the World Cup? Airport robots, of course.
A pilot program at the San José Mineta airport has a humanoid robot from @intbotai greeting travelers, answering questions about flights and baggage in more than 50 languages.
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The integration layer is where robots succeed or fail.
Airports are the perfect testing ground, where the infrastructure changes every second.
Flight delays. Gate changes. Background noise and surges of passengers.
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Silicon Valley’s airport robot will pique the curiosity of this summer’s World Cup visitors. But it’s really about testing if AI systems can adapt to decades-old infrastructure and keep up in real time.
Full piece by @BerryWrites: infiniteloop.media/p/why-hum…
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One developer. Six months of building. $80M exit. @MaorShlomo created Base44 and sold it to Wix — now anyone can use his platform to do the same thing.
Vibe coding platforms have removed the technical barrier to building software.
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To build a breakout app, you need a deep understanding of the edge cases, trust dynamics and regulatory constraints. It’s about making hundreds of small decisions that lead to the right features and the right market fit.
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@MaorShlomo discusses the vibe coding era in this piece by @abracarioca: infiniteloop.media/p/dude-wh…
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The Infinite Loop retweeted
May 24
The two most common questions i get are “what’s the secret to success in the vibe coding era” and “if anyone can build now how can you have a moat”
I enjoyed talking about it with @abracarioca from @RunInfiniteLoop and trying to give my 2 cents
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99% of infrastructure traffic is coming from agents. 2 years ago it was 10%.
Pretty much all the code being produced is generated by agents now, says Nikita Shamgunov @nikitabase, VP at @databricks and founder of @neondatabase (now Lakebase).
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In the agentic era, AI isn’t just changing how software is built. It may dismantle SaaS itself.
Shamgunov, for one, is preparing for the SaaS apocalypse. You have to be “extremely paranoid,” he says.
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Every SaaS company is now deciding how to become infrastructure for AI agents — or get replaced by them.
The Infinite Loop sat down with @nikitabase to find out what’s changing, what keeps him up at night, and what will follow the age of agents.
infiniteloop.media/p/the-ris…
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