Machine Learning and Drug Discovery at @AstraZeneca (views my own). PhD @durham_uni, passed through @computingncl, @gliffai, @CriteoAILab
Joined May 2014
- Tweets 287
- Following 362
- Followers 174
- Likes 156
3 Photos and videos
Stephen Bonner retweeted
3 Oct 2022
Broadcasting, reshaping, repeating, and squeezing in @PyTorch is tricky business. Thanks to @SBonner0 for identifying some room for improvement in our implementation of Margin Ranking loss
🔗 PR: github.com/pykeen/pykeen/pul…
#machinelearning #ai #artificialintelligence #opensource
4
5
Stephen Bonner retweeted
11 Jan 2022
🚨 PyKEEN 1.7.0 is out! 🚨
New: 7 models, 3 encoders, 2 trackers, keras-style training callbacks, uncertainty estimation, and more
📖 Full Release Notes: github.com/pykeen/pykeen/rel…
💪 Huge S/O to external contributors @dobraczka @michael_galkin @SBonner0 @Ralph_Abb and others
1
14
29
14 Dec 2021
Happy to present a new paper today at @lmrl_bio, held at @NeurIPSConf. The paper explores how topological imbalance in drug discovery knowledge graphs can affect models trained upon them and is joint work with Ufuk Kirik, Ian Barrett, Ola Engkvist and Jian Tang.
2
8
Stephen Bonner retweeted
3 Dec 2021
Delighted to have won the Best Partnership Alliance for our work with @AstraZeneca at the prestigious #ScripAwards.
Our teams work side-by-side to combine AI & scientific expertise to discover novel targets for #CKD & #IPF.
Learn more: benevolent.com/news/a-new-er… @PharmaScrip
4
18
29 Nov 2021
An updated version of "A Review of Biomedical Datasets Relating to Drug Discovery: A Knowledge Graph Perspective" with I Barrett, C Ye, R Swiers, O Engkvist, @AndreasBenderUK, @cthoyt and W Hamilton has been released.
Paper: shorturl.at/ehDS0
Repo: shorturl.at/fgC24
1
1
12
29 Nov 2021
New for this version is the associated github repo collecting all the relevant resources, papers and dataset links into one location. This repo will continue to be updated as new resources are released.
1
29 Nov 2021
For those having issues with the shortened paper URL, here in the full link: arxiv.org/abs/2102.10062
Stephen Bonner retweeted
14 Sep 2021
Want to learn about applications of graphs in the industry?
🚀Then, register for our Graph #MachineLearning in Industry workshop on 23rd September⬇️
sites.google.com/view/graph-…
13
30
Stephen Bonner retweeted
Global disparities in COVID-19 genomic surveillance between high-, middle- and low-income countries 🦠🌎🧬. See original post by @AndersonBrito_ and the preprint medrxiv.org/content/10.1101/…. Please share your thoughts, comments and questions with us!
27 Aug 2021
Do you know that only ~6% of the SARS-CoV-2 genomes submitted to GISAID (up to July 20th) came from low- and middle-income countries? 🌎🧬
In this study we discuss the causes, consequences and possible solutions for disparities in SARS-CoV-2 genomic surveillance. 🧵👇
2
8
Stephen Bonner retweeted
4 Aug 2021
Google, what the hell is this?
40
604
4,141
EMBL and @DeepMind have partnered – a breakthrough for science.
Together, we're providing a treasure trove of protein structure predictions powered by #AlphaFold to herald a new era for #AI-enabled biology.
embl.org/news/science/alphaf…
ALT Protein structures representing the data obtained via AlphaFold.
21
691
1,754
Stephen Bonner retweeted
29 Jun 2021
We are happy to see that PyKEEN is adopted within research and industry projects. Recently, PyKEEN has been used within @AstraZeneca to analyze the potential of knowledge graph embedding models for drug discovery: arxiv.org/pdf/2105.10488.pdf
#knowledgegraphembeddings
3
10
35
Stephen Bonner retweeted
8 Jun 2021
Was reading the @benevolent_ai knowledge graph paper by @sgpaliwal et al and thought it would help my understanding to draw a metagraph. So here it is:
Paper: doi.org/gg49
Metagraph: git.io/JZOHB
ALT Metagraph of the Benevolant AI knowledge graph in Paliwal et al 2020
2
9
Stephen Bonner retweeted
2 Jun 2021
We just merged a nice external contribution from @SBonner0 to use @TensorBoard as a tracker 🚀
📖 Tutorial: pykeen.readthedocs.io/en/lat…
🖥️ Code: github.com/pykeen/pykeen/pul…
1
8
Stephen Bonner retweeted
30 May 2021
Researchers at @AstraZeneca's Data Sciences & Quantitative Biology Unit combine #Hetionet, #Pharmaprojects, and @OpenTargets to predict disease-target relationships. Excited to give this a deeper read! arxiv.org/abs/2105.10578
ALT Figure 3: Schema of the proposed model.
6
35