Disease Unit for Myocarditis & Arrhythmogenic Cardiomyopathies at @SanRaffaeleMI @SRArrhythmology
Joined September 2022
- Tweets 24
- Following 134
- Followers 113
- Likes 52
2 Photos and videos
We are proud to announce that our research project GEAM: yield of GEnetic testing in Arrhythmic Myocarditis, led by Dr. Giovanni Peretto, was funded with the Early Career Award by Fondazione Regionale per la Ricerca Biomedica (FRRB) and Regione Lombardia. hsr.it/news/2024/luglio/band…
2
2
4
522
We propose a research project aimed at: 1) defining the prevalence of CGVs with arrhythmic myocarditis, with a special focus on gender differences; 2) describing the prognostic value of CGVs; (...)
1
56
3) identifying gene expression profiles associated with ventricular arrhythmias through transcriptomics on cardiac tissue, in order to investigate possible therapeutic targets for personalized care.
48
We explored pentraxin 3 (PTX3), an acute phase protein, as a potential biomarker in plasma and cardiac biopsies of patients with myocarditis.
#myocarditis
link.springer.com/article/10…
1
2
6
320
💡Cardiac tissue analysis revealed PTX3 expression in all patients, with viral myocarditis exhibiting higher signal intensity than autoimmune myocarditis, and with a predominant localization in cardiomyocytes.
1
65
💡Abnormal plasma PTX3 was associated with systolic dysfunction and heart failure at presentation. Interestingly, patients who recovered by 12 months had higher baseline PTX3 levels. Our preliminary data support the potential use of PTX3 as a biomarker in myocarditis.
56
San Raffaele Myocarditis & Cardiomyopathies retweeted
20 Mar 2024
#Tomorrow🎯Join us online! Prof. Antonio Esposito @DoctorAntoExpo 🇮🇹 is our guest at Grand Round #CVImaging to explore what #YesCCT can offer by Late Enhancement & ECV quantification! With our hosts🎙️Profs. Manka @rmanka_ & Alkadhi @Alkadhi_rad - @Unispital_USZ 🫀
❣️@SRMyocarditis @SanRaffaeleMI @KateHanneman @DrMarthaGulati @YoungDgk @DGK_org #WhyCMR @SCMRorg @CotSwiss @SwissCardio @VDelgadoGarcia @EACVIPresident @UHN @UZAnieuws @andgiannopmd @ErsozluSara @EscrOffice @marco_francone @BSCMR @BoldiKovacsMD @ASaguner @DavidNiederseer @Chrigi_Schmied @JGrapsa @iamritu @HanCardiomd @mjschuuring @KemalogluOz @alessia_gimelli @PCRonline @ShehabAnwer @Hragy @drahmedmohsen85 @UZH_en @ETH_en @CTECresearch @GoricaEra @ShehabAnwer @BadertscherPat @BarbaraStahli @ErsozluSara @EZancanaroMD @ShehabAnwer
ALT Antonio Esposito is Full Professor of Radiology at Università Vita-Salute San Raffaele and Deputy Scientific Director of IRCCS Ospedale San Raffaele, where he is also Deputy-Director of the Experimental Imaging Center and Scientific Director of the Clinical Trial Center. He has long time experience in the field of body application of advanced imaging with MRI and CT, with a particular focus on cardiovascular and oncological applications. He developed an intensive clinical and preclinical research on these issues, with more than one hundred manuscripts published in peer-reviewed journals. He leads the Preclinical Imaging Facility of the SRSI, a service and research facility equipped with CT, MRI, Optical and US imaging technologies dedicated to the experimental study of small animal models of diseases.
8
19
2,300
San Raffaele Myocarditis & Cardiomyopathies retweeted
27 Sep 2023
Amazing appointment to share and spread the knowledge about #Fabry disease 💫
Old friends, beautiful city #naples, excellent organization!
#FabryAcademyforYoungDoctors 🌟
#CardioEd #Cardiotwitter #MedEd
@CriChimenti @glimongelli @mauripieroni72 @OssMalattieRare
6
31
1,403
San Raffaele Myocarditis & Cardiomyopathies retweeted
31 Jul 2023
July 2023 @CardioZurich 🫱🏻🫲🏼 Kornienko et al reports novel therapy target 🔎 dilated #cardiomyopathy ⭐️ @ASaguner
🌐nature.com/articles/s41467-0…
@NatureComms @SRMyocarditis @CardiologyToday @CardioNerdsJC @EHRAPresident @HFA_President @andgiannopmd @HanCardiomd @CTECresearch
21 Jul 2023
Kornienko et al. @NatureComms 🔎TNPO3 & RBM20 interactions ⏩️ novel #therapy 🎯 Dilated #Cardiomyopathy #DCM ⏩️ nuclear localization alleviates #phenotype!
👏🏻 @chad_mao @tikuowens @ASaguner @vnparikh @MitchGotthardt @LarsMSteinmetz @ASaguner #CardioTwitter #Cardiology
ALT Splice-regulatory activity of RBM20 variants is proportional to their nuclear localization. Proof-of-principle for developing therapeutic strategies to restore RBM20’s nuclear localization in RBM20-DCM patients
5
6
1,284
San Raffaele Myocarditis & Cardiomyopathies retweeted
29 Jul 2023
Detecting and targeting inflammation in genetic cardiomyopathies: Are we there yet?
Read the editorial by @spinneymd & @DLMann_MD on the new #JACCBTS study by @GiovanniPeretto & colleagues: bit.ly/47mwHyL
#HeartFailure #CardioRheum #CardioTwitter
1
7
13
7,367
San Raffaele Myocarditis & Cardiomyopathies retweeted
30 Jul 2023
A very important study. Inflammation in the heart, in the context of LV dysfunction, cannot be a good thing. More data is needed, but this study gives us some light #cardiacimmunology
25 Jul 2023
Use of multimodal imaging in genetic cardiomyopathies may allow for the identification of myocardial inflammation potentially responsive to immunomodulatory therapy.
Read the new #JACCBTS study by @GiovanniPeretto et al here: bit.ly/3Y7BTSI
#HeartFailure #CardioRheum
2
15
2,006
San Raffaele Myocarditis & Cardiomyopathies retweeted
25 Jul 2023
Use of multimodal imaging in genetic cardiomyopathies may allow for the identification of myocardial inflammation potentially responsive to immunomodulatory therapy.
Read the new #JACCBTS study by @GiovanniPeretto et al here: bit.ly/3Y7BTSI
#HeartFailure #CardioRheum
2
107
241
41,625
San Raffaele Myocarditis & Cardiomyopathies retweeted
18 Jul 2023
Dr. @GiovanniPeretto, et al investigate the prognostic value of genetic testing and histology in a cohort of undefined left ventricular arrhythmogenic #cardiomyopathy patients ➡️ bit.ly/3Y4tyz9
#JACCCEP #EPeeps #MACE #CardioTwitter
19
49
10,653
Our new pilot report of 25 patients with genetic cardiomyopathy and biopsy-proven myocardial inflammation. M-Infl was characterized by multimodal imaging, including CMR and PET, and treated with immunomodulatory therapy for the first time in NGS patients. doi.org/10.1016/j.jacbts.202…
1
3
4
396
Functional characterisation of the rare SCN5A p.E1225K variant, segregating in a Brugada syndrome familial case, which caused an impairment of the mutated Nav1.5 in human cardiomyocytes from pluripotent stem cells.
doi.org/10.3390/ijms24119548
4
8
511
From bedside to the bench, the role of myocardial inflammation (M-Infl) is emerging in the pathophysiology, phenotype, and treatment of traditionally genetic cardiomyopathies (DCM/ACM). Check our "hot off the press" review!
doi.org/10.3390/biom13040646
2
4
412