Scientist

Joined October 2012
130 Photos and videos
Pinned Tweet
Proud to share our latest work led by X-less Oliver Dutton! We've demonstrated that inverse folding models can be substantially improved at protein stability prediction without additional training or data. 1/4
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New preprint with @inve_michele, @SSadnro, @KamilTamiola, and @LindorffLarsen on atomistic simulations of disordered proteins, using enhanced sampling to uncover some order within disorder. biorxiv.org/content/10.64898…
Transient tertiary structure in intrinsically disordered proteins revealed by multithermal enhanced sampling biorxiv.org/content/10.64898… #biorxiv_biophys
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Sandro Bottaro retweeted
Sampling IDPs is tough, but can be worth the effort! OPES multithermal made it a little easier for us, hopefully you'll find it useful as well @PeptoneLtd
New preprint with @inve_michele, @SSadnro, @KamilTamiola, and @LindorffLarsen on atomistic simulations of disordered proteins, using enhanced sampling to uncover some order within disorder. biorxiv.org/content/10.64898…
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Sandro Bottaro retweeted
Transient tertiary structure in intrinsically disordered proteins revealed by multithermal enhanced sampling biorxiv.org/content/10.64898… #biorxiv_biophys

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Walking around Naples in a Juventus shirt…. With Maradona on the back 😂

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Hey @Ryanair @Ryanair_IT two months trying to get assistance for my dad disabled & on dialysis. Radio silence. We’re not asking for VIP perks, just basic human support.
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Still no word from @Ryanair_IT @Ryanair but at least the scammers are showing real interest in my case. Nice to know someone cares
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@Ryanair is this account legit?
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Maybe @Google or @GoogleDeepMind should fund CASP, given their ample resources and how much they've benefited from the efforts of John Moult, Krzysztof Fidelis, Andriy Kryshtafovych, Nick Grishin, and many others. science.org/content/article/…
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Sandro Bottaro retweeted
Please RT! I have 2 postdoctoral positions in my lab @BRFAA_IIBEAA to work on MD sims for protein allostery, cryptic pocket identification, CADD/FEP. Knowledge in coarse-grained MD is a plus. More info: linkedin.com/hiring/jobs/424…. Send me an email with your CV if interested!
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Un caro ringraziamento a @SEA_Press per averci abbandonato sulla pista di Malpensa alle due di mattino
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🚨 Program Update: CADD GRS 2025! We're excited to welcome @wpwalters as our keynote: "AI in Drug Discovery – Revolution, Evolution, or Complete Nonsense?" A perfect kickoff for an inspiring weekend in Portland! 🔗 grc.org/computer-aided-drug-… #CADDGRS2025 #compchem #DrugDesign

23 May 2025
🏁 Program is live for the 2025 GRS on Computer-Aided Drug Design! Overwhelming interest, top-tier abstracts, and a fantastic lineup incl. keynote Charlotte Deane stellar mentorship panel. Can't wait! 🔗 grc.org/computer-aided-drug-… #CADDGRS2025 @GordonConf #CompChem #DrugDesign
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Just published in @NatureComms our new paper integrating #MD and #cryoEM data to construct structural ensembles of complex #RNA macromolecules 🎉✨🥳nature.com/articles/s41467-0…. Excellent work by @ElisaPos with @BussiGio @BonomiMax @PJanosJr N. Toor, D. Haack
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Il barolo ce lo terremo per noi youtu.be/aaZZxHiidNk?feature…

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#RNA rules
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Interested in #RNA modelling across multiple scales? Join us for the @cecamEvents meeting at @Sissaschool, Trieste, May 19-22! cecam.org/workshop-details/r… We still have slots for contributed talks. Deadline March 23. Co-organized with @Magistrato_Lab and @devivo_marco

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Sandro Bottaro retweeted
I’m delighted to share that @ThomasLhr1, @gogulan_k, and I are launching @bindresearch, a UK-based not-for-profit research startup to deliver publicly–available tools and datasets to make intrinsically disordered proteins druggable. 🍝 💊🧲 💻 🦠
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Oggi è il compleanno di Angelo Badalamenti, il che significa che è il giorno perfetto per condividere per l'ennesima volta il video più bello di tutto l'Internèt: quello in cui racconta di come lui e Lynch hanno scritto il tema musicale di Laura Palmer.
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We discovered 3 RNA families that form homo-oligomeric RNA-only complexes! Studying nature continues to expand my wildest imagination. Read about it: doi.org/10.1101/2024.12.08.6… Vivian Wu, Svetlana Shabalina, Hyunbin Lee, Grace Nye, Eugene Koonin, Alex Gao, @RDasLab @chiulab
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Anubi era un alieno che veniva dalla costellazione del canis poi sono tornati nelle loro galassie e gli antichi egizi hanno detto che era il protettore dei defunti ma non era vero
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