Scientists created a drug that lets humans regrow lost teeth naturally 🦷
Researchers in Japan, led by Dr. Katsu Takahashi at the Medical Research Institute Kitano Hospital, have developed a pioneering medication that stimulates the natural regrowth of teeth.
The drug works by blocking a protein called USAG-1, which normally suppresses tooth development in humans. Having already successfully triggered the growth of brand-new teeth in mouse trials, the research team is now preparing to initiate human clinical trials, aiming to make this transformative treatment commercially available within the decade.
This innovative therapy builds on decades of regenerative medicine and the discovery that humans possess dormant, 'third set' tooth buds, much like sharks or elephants that naturally grow multiple sets of teeth.
When combined with ongoing advances in bone and dental pulp regeneration, scientists believe this approach could eventually reverse tooth loss caused by genetics, injury, or aging, transforming dental care forever.
source: Ravi, V., Murashima-Suginami, A., Kiso, H., Tokita, Y., Huang, C.L., Bessho, K., Takagi, J., Sugai, M., Tabata, Y., & Takahashi, K. Advances in tooth agenesis and tooth regeneration. Regenerative Therapy, 22, 160–168.
ALT Scientists created a drug that lets humans regrow lost teeth naturally 🦷
Researchers in Japan, led by Dr. Katsu Takahashi at the Medical Research Institute Kitano Hospital, have developed a pioneering medication that stimulates the natural regrowth of teeth.
The drug works by blocking a protein called USAG-1, which normally suppresses tooth development in humans. Having already successfully triggered the growth of brand-new teeth in mouse trials, the research team is now preparing to initiate human clinical trials, aiming to make this transformative treatment commercially available within the decade.
This innovative therapy builds on decades of regenerative medicine and the discovery that humans possess dormant, 'third set' tooth buds, much like sharks or elephants that naturally grow multiple sets of teeth.
When combined with ongoing advances in bone and dental pulp regeneration, scientists believe this approach could eventually reverse tooth loss caused by genetics, injury.