Gracias ACI-SEC Congress 2026: see you next time! ACI-SEC Congress proved to be the place to be for meaningful conversations, workshops on #ComplexPCI and live cases showcasing #ShockwaveC2Aero. We were proud to welcome so many of you at our booth to explore our latest innovation and discuss how we continue to advance patient care. ACI-SEC Congress delivered valuable moments of learning and exchange, and we return home inspired and grateful for the insights shared. @GuillermoSchez @pablo_bazal @Octavio_JiMelo US Rx only. Safety Info: shockwavemedical.com/isi/ Product availability may vary by country.

DRES Congress: the perfect launchpad for #ShockwaveC2Aero Thank you to all the healthcare professionals who visited our booth and engaged in hands-on training with Shockwave C2 Aero. It was a pleasure to showcase our newest #ShockwaveIVL catheter and explore its deliverability model together. The energy, curiosity, and meaningful conversations throughout the congress made this launch in the Netherlands truly special. Thank you for being part of this milestone: together, we’re shaping the future of coronary calcium treatment and enabling better patient outcomes. US Rx only. Safety Info: shockwavemedical.com/isi/ ​ Product availability may vary by country.

When you see coronary calcium, what questions do you ask yourself? That's where CALC comes in — see calcium, think CALC!​ 🟡 Is compliance adequate?​ 🟡 What factors inform device selection? ​ 🟡 When is #ShockwaveIVL suitable?​ Answers to these important questions will help inform the next steps of your intervention, including which calcium modification devices you select.​ Learn more about CALC: shockwavemedical.com/en-eu/c… ​ US Rx only. Safety Info: shockwavemedical.com/isi/?ut… ​Product availability may vary by country.

Patients with CLTI face severe arterial calcification and high clinical complexity. For those on dialysis, overall mortality risk is high — often independent of limb intervention. #DisruptBTKII demonstrates the value of #ShockwaveIVL revascularization in a complex patient population, including patients on dialysis and with CLTI, aligning with patient-centered goals like limb preservation and symptom relief. Learn more about this study: shockwavemedical.com/clinica… 1 Armstrong E, VIVA 2025 US Rx only. Safety Info: shockwavemedical.com/isi/?ut… Product availability may vary by country.

For International Physicians: New real-world evidence on #ShockwaveReducer: Coronary sinus reducer implantation for refractory angina: a national audit of UK practice A major UK national audit just published in @Heart_BMJ reinforces the value of #ShockwaveReducer implantation in patients with refractory angina despite optimised medical therapy. Across 19 centres, results confirm that #ShockwaveReducer is being implemented in line with guideline recommendations in real-world clinical practice, translating into meaningful clinical outcomes for patients. As shown in the figure, there is a clear shift in the distribution of CCS class from baseline to 6 months, with more patients moving to lower angina severity classes, reflecting an overall improvement in symptoms: 🔶 75% improved ≥1 CCS class 🔶 36% improved ≥2 CCS classes These findings highlight the ability of Shockwave coronary sinus reducer to significantly improve angina symptoms and quality of life in a highly symptomatic population with limited treatment options. Congratulations to all authors, Cheng, K., @fwitherow, Byrne, J., Lindsay, S., @drtpatterson, @K_DeSilva, @ranildesilva2 and collaborating centres for this important contribution to real-world evidence and the continued advancement of care in refractory angina. Read the abstract here: heart.bmj.com/content/early/…  Safety Info:  shockwavemedical.com/isi/ CAUTION: Investigational Device. Limited by U.S. and Canadian law to investigational use. The Reducer is commercially available in certain countries outside the U.S. and Canada.

Thank you to those who joined us in NYC for New Wave Academy: Interventional Cardiology Fellows! ⚡🌊 This one-day event brought fellows together for interactive skill-building, case-driven discussions and practical clinical perspectives to help strengthen confidence in managing complex coronary & peripheral disease. Grateful to our expert faculty: Prof @ziadalinyc, Dr @SripalBangalore, Dr @RhianEDavies1, Dr @DougDrachmanMD, Dr @yourheartdoc1, Dr Kathleen Kearney, Dr Arber Kodra and Dr @dhkiss2 Presenting physicians are paid consultants of Shockwave Medical. US Rx only. Safety Info: shockwavemedical.com/isi/ Product availability may vary by country.

For Healthcare Professionals Only: Shockwave C2 Aero marks an important milestone in Portugal with the first cases performed at ULS Santo António! With its high deliverability and precision, #ShockwaveC2Aero is redefining the approach to complex coronary lesions, driven by continuous innovation in intravascular lithotripsy. These early cases highlight the real-world impact of the technology and reinforce Portugal’s role in advancing the treatment of coronary calcium in Europe. For professional use only. US Rx only. Safety Info:  shockwavemedical.com/isi/ Product availability may vary by country. Instructions for use:  shockwavemedical.com/ifu/

In a recent @EVToday article, Dr Manolo Rubio discusses his real-world experiences with #ShockwaveJavelin: “[this] is a new tool I can now reach for when calcium is the final barrier between the patient and a meaningful chance at limb preservation.” Crack into all of Dr Rubio’s takeaways and case details now: evtoday.com/articles/2026-ma… Featured physicians are paid consultants of Shockwave Medical. US Rx only. Safety Info: shockwavemedical.com/isi/ Product availability may vary by country.

Hola Pamplona: Shockwave C2 Aero arrives at ACI-SEC Congress 2026! From 10-12 June, #ACI-SEC2026 brings together the interventional cardiology community for three days of innovation: 🔬 10 June, attend our Workshops #4 on Complex PCI ⚡ 11 June, experience a Live Case featuring #ShockwaveC2Aero, showcasing its application in real-world practice Curious to learn more about #ShockwaveIVL? Visit our booth to explore the new features of Shockwave C2 Aero and connect with our team. See you at ACI-SEC 2026: let’s crack some calcium together! US Rx only. Safety Info:  shockwavemedical.com/isi/ Product availability may vary by country.

#ShockwaveC2Aero makes waves to the Netherlands! Join us at DRES Congress on 11–12 June and discover Shockwave C2 Aero, our latest innovation designed to address coronary calcium. Visit our booth to explore its unique mechanism of action and see firsthand how its deliverability model supports confident, controlled treatment. Our team will be on hand to walk you through its technology and answer your questions. We look forward to engaging in meaningful conversations on advancing calcium treatment. US Rx only. Safety Info: shockwavemedical.com/isi/ ​ Product availability may vary by country.

EuroVASC in Lisbon: what an energizing two days! We were proud to be part of EuroVASC and to host a compelling session exploring how #ShockwaveIVL is redefining pre TAVI access strategies. A big thank you to Dr. Luis Raposo for leading a deep dive into real world insights, and to everyone who joined the conversation. Together, we are not just treating calcium, we are pushing boundaries and shaping what’s next in vascular care. Presenting physicians are paid consultants of Shockwave Medical. US Rx only. Safety Info: shockwavemedical.com/isi/ ​Product availability may vary by country.

Join Drs @NickMouawadMD, @RaviNAmbani, Kaitlyn Rountree and @CincyVascSurg for a cracking good CLTI webinar on June 23 at 6:00 pm Central. Sponsored by #ShockwaveIVL and presented by @MWVSSociety, “Challenging BTK Anatomy in CLTI: The Case for IVL-First Therapy” will cover anatomical challenges, clinical evidence and real-world application of #ShockwaveE8 and #ShockwaveJavelin for first-line complex BTK calcium treatment. Register today: us06web.zoom.us/webinar/regi… US Rx only. Safety Info: shockwavemedical.com/isi/ Product availability may vary by country.

For Healthcare Professionals Only: #ShockwaveC2Aero makes its debut in Spain! The first cases in Spain mark an important milestone in the treatment of coronary calcium and for the Spanish interventional cardiology community. Early experience highlights how innovation can support physicians in addressing complex coronary lesions with greater precision. By enabling controlled and efficient calcium modification, Shockwave C2 Aero is helping refine daily practice where it matters most. We’re proud to support Spanish clinicians as they continue advancing patient care. @cardioyoguini @MuntaneCarol @JuradoRomanAl @RaulmorenoMD @MattiaBasile97 @hemodin90 @NievesGonzalo1 @AlejandroTrav @pabl0salinas @beavaquerizo @hcuberogallego @JoanFAndres Shockwave C2 Aero is a CE marked medical device (CE2797). For professional use only. US Rx only. Safety Info: shockwavemedical.com/isi/ Product availability may vary by country. Instructions for use: shockwavemedical.com/ifu/

Congratulations to Dr. Bilal Murad (@BilalMuradMD1) and the Team at United Hospital in St. Paul, Minnesota for joining the growing number of #COSIRAII enrolling sites and successfully enrolling their first patient in the trial. Want to learn more about the COSIRA-II trial and the participating sites? Visit clinicaltrials.gov  Safety Info: shockwavemedical.com/isi/​ CAUTION: Investigational Device. Limited by U.S. [and Canadian law] to investigational use.

Big news — Shockwave #CoronaryIVL is now covered by Aetna. Aetna’s new policy considers #ShockwaveIVL medically necessary for the treatment of hemodynamically significant, heavily calcified coronary stenoses where primary stenting is not possible. This change expands access to medically necessary care for more than 20 million covered lives across the U.S. We’re proud to help lead the way in sparking broader access to safe, effective calcified CAD treatment for the patients who need it most. Learn more about #ShockwaveIVL for Coronary Artery Disease on our website: shockwavemedical.com/disease…  US Rx only. Safety Info: shockwavemedical.com/isi/ Product availability may vary by country.

New #DisruptBTKII sub-analysis data confirm #ShockwaveIVL’s impact extends to patients on dialysis, helping preserve limbs and improve quality of life when it matters most. Learn more about DISRUPT BTK II: shockwavemedical.com/clinica…  Holden A, Charing Cross Symposium 2026 US Rx only. Safety Info: shockwavemedical.com/isi/ Product availability may vary by country.

Don’t miss our OPCI Coronary Observation Course from June 14 – 15th led by Prof Ziad Ali (@ziadalinyc), and Drs Allen Jeremias (@DrAllenJ) and Evan Shlofmitz (@ESHLOF). During this two-day program, you’ll gain a deeper understanding into the latest in complex PCI treatment strategies within a select, small group setting — including how to integrate intravascular imaging and #ShockwaveIVL into your calcium modification workflow — through live case observation, didactics and interactive discussion. Register today to attend this exciting course at St. Francis Hospital & Heart Center: web.cvent.com/event/8e0b5f19…  Presenting physicians are paid consultants of Shockwave Medical. US Rx only. Safety Info: shockwavemedical.com/isi/ Product availability may vary by country.

Are you ready to join the CIRSE webinar “Cracking the complexities of BTK disease”? Prof. Maria Antonella Ruffino (@maruffino73), Dr. Raghuram Lakshminarayan, Dr. Narayanan Thulasidasan and Dr. Christian Wissgott will guide an educational session focusing on complex BTK disease, its challenges and when to use #ShockwaveIVL. Still not registered? Registration is free and open to everyone: cirse.org/online/cirse-webin… #CIRSE @CIRSEsociety US Rx only. Safety Info: shockwavemedical.com/isi/ Product availability may vary by country.

For Healthcare Professionals Only: We’re excited to announce the first cases of #ShockwaveC2Aero in Italy! Early clinical experience is already showing very encouraging feedback, reinforcing the value of innovation in the treatment of complex coronary calcium. We’re proud to stand alongside Italian interventional cardiologists as they advance everyday clinical practice, with the shared goal of improving patient outcomes and quality of care. @GLGasparini, @MarcoPavani0, Stefano Galli Shockwave C2 Aero is a CE marked medical device (CE2797). For professional use only. US Rx only. Safety Info: shockwavemedical.com/isi/ Product availability may vary by country. Instructions for use: shockwavemedical.com/ifu/

Welcome to the Aero Era. 🏹 Hear how Dr Brett Wanamaker(@BWanamakerMD) used #ShockwaveC2Aero to treat this tortuous proximal-mid LAD lesion. 🔗 Learn more about Shockwave C2 Aero:  shockwavemedical.com/product… US Rx only. Safety Info: shockwavemedical.com/isi/ Product availability may vary by country.