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Shmuel Shoham @ShohamTxID

Working on therapies for prevention and treatment of coronavirus. Transplant Infectious Diseases physician at Johns Hopkins. @ShohamTxID@med-mastodon.com

Joined May 2015
  • Tweets 10,565
  • Following 1,304
  • Followers 8,790
172 Photos and videos
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Shmuel Shoham@ShohamTxID
3 Mar 2018
At our best infectious diseases experts can act as the synapses that connect surgeons, internists, pharmacists, microbiologists, epidemiologists and the patients to make good decisions.
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"Crude 30-day mortality following a positive COVID-19 test was 2.2% in 2020, then decreased before stabilizing to 0.8%–1.0% from 2023 onward." Some people forget just how bad COVID was back then. academic.oup.com/ofid/articl…~

Trends in Coronavirus Disease 2019 Mortality Within a US Academic Health System, 2020–2025

Abstract. Coronavirus disease 2019 (COVID-19) was initially associated with higher mortality than other respiratory viruses. We assessed trends in mortalit

academic.oup.com
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Triazole-resistant Aspergillus fumigatus in the Netherlands between 1994 and 2022: a genomic and phenotypic study - The Lancet Microbe thelancet.com/journals/lanmi…

Triazole-resistant Aspergillus fumigatus in the Netherlands between 1994 and 2022: a genomic and...

Our study showed variation in triazole genotypes and phenotypes in clinical A fumigatus isolates with cyp51A-mediated resistance, some of which were cultured from triazole-resistant invasive asperg...

thelancet.com
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Two Pandemics, Compared: Reflections on HIV and COVID-19 blogs.jwatch.org/hiv-id-obse…

Two Pandemics, Compared: Reflections on HIV and COVID-19

“Dr. Sax, what’s it like to have lived through two pandemics as an ID doctor?” The question came from a brand-new intern during afternoon sign-out. I took a breath — because wow, were they different....

blogs.nejm.org
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Shmuel Shoham retweeted
Fahad Buskandar@f_buskandar
3 Jun 2025
A great opportunity for those wanting to learn and update themselves about infections in transplant and oncology patients.
Shmuel Shoham@ShohamTxID
3 Jun 2025
hopkinsmedicine.org/infectio… We are excited about this course. We are sure @Contagion_Live readers will find this course worthwhile
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hopkinsmedicine.org/infectio… We are excited about this course. We are sure @Contagion_Live readers will find this course worthwhile

Pamela Tucker Course in Transplant & Oncology Infectious Diseases

hopkinsmedicine.org
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Aspergillus tanneri fast facts: Tends to be resistant to multiple antifungal agents, described in people with chronic granulomatous disease (CGD) Western parts of US, living in Western parts of the US. Disseminated and contiguous disease patterns
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Clinical situation: should you use vancomycin as part of empiric therapy in patient with AML and pneumonia. Answer from clinical trial: Not typically, if MRSA screen is negative - Talagtag - 2021 - Transplant Infectious Disease - Wiley Online Library onlinelibrary.wiley.com/doi/…

Utility of methicillin‐resistant Staphylococcus aureus (MRSA) nasal screening in patients with...

Background Current literature has demonstrated the utility of the MRSA nasal screen as a de-escalation tool to decrease unnecessary anti-MRSA antibiotic therapy. However, data on the applicability...

onlinelibrary.wiley.com
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Candida auris: a) adheres to skin and inanimate objects, b) colonization often clinically significant (compared to C. albicans), c) associated with outbreaks, d) often resistant to fluconazole, and sometimes echinocandins too. A good review article by Lionakis in NEJM in 2024
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Teaching case: middle aged man with ulcerative colitis. Disease has been stable, but now seemingly flares. CMV viral load ~100K. Endoscopy: CMV colitis. CMV IgG had been negative previously. Now CMV IgM . This is probably primary CMV infection with tissue invasive disease
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For a patient in whom there is a high pre-test probability for Clostridium difficile infection: a positive C difficile PCR with a negative EIA for toxin, does not rule out C difficile. False negative tests for the EIA toxin do occur.
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ID quiz: pt with neutropenia and blood culture with Rhodotorula. What is your fist line antifungal therapy
9% micafungin
0% fluconazole
73% amphotericin B
18% posaconazole
11 votes • Final results
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most people voted for AmB, which would be my choice too
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Aspergillus calidoustus. I have seen it have a tendency for cutaneous involvement. Tends to be resistant to azoles. Here is another one from the literature. rdcu.be/eg2Fr.

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more about this organism and the skin Seroy J, Antiporta P, Grim SA, Proia LA, Singh K, Clark NM. Aspergillus calidoustus case series and review of the literature. Transpl Infect Dis. 2017 Oct;19(5). doi: 10.1111/tid.12755. Epub 2017 Sep 19. PMID: 28741738.
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Shmuel Shoham retweeted
Molecular Microbiology and Immunology@JohnsHopkinsMMI
28 Mar 2025
Thank you to today’s panel of MMI Thursday Seminar presenters — David Sullivan, MD, & our guests from @HopkinsMedicine moderator Dan Hanley, MD, @ShohamTxID, Nicole McBee & Karen Lane! Great interactive discussion about their multi-center #COVID-19 clinical trial
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Estimates of actual and potential lives saved in the United States from the use of COVID-19 convalescent plasma | PNAS pnas.org/doi/10.1073/pnas.24…

Estimates of actual and potential lives saved in the United States from the use of COVID-19...

In the Spring of 2020, the United States of America (USA) deployed COVID-19 convalescent plasma (CCP) to treat hospitalized patients. Over 500,000 ...

pnas.org
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share.transistor.fm/s/e9646a… new episode up: invasive candidiasis

Topic review: Invasive candidiasis | Transplant ID Cast | Episode 33

Tune in to this episode of the Transplant ID podcast for a case based learning module on the topic of invasive candidiasis and its therapy.

share.transistor.fm
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many reasons why life expectancy in US is falling. I have to imagine the painfully system for getting medications covered by insurance companies is one of them. Without A LOT of work on the part of patients there are a million ways that things don't work out.
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idsociety.org/news--publicat… via @IDSAInfo Changes are needed badly. Thank you IDSA for working on this

IDSA Calls for Substantive Changes to ABIM’s MOC Program

idsociety.org
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amongst the best of Israel right here in this video
Alaa Atamna@AlaaAtamna
6 Nov 2023
על משמרתכם הופקדנו יומם ולילה
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