@SivaramanLab profile picture
Sivaraman Padavattan @SivaramanLab

Additional Professor, Department of Biophysics @NIMHANS_BLR | Research interest: Alzheimer's disease, Parkinson's disease, Chromatin, Structural Biology

Joined February 2010
  • Tweets 87
  • Following 516
  • Followers 214
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Sivaraman Padavattan retweeted
Sneha@Jos_sneha
Jan 25
Our work proposing an early-stage model that challenges the traditional aggregation-centric views for protein deposit (Lewy body) formation in Parkinson's Disease was featured in The Hindu today ! Link: nature.com/articles/s42003-0…
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Our latest study in @CommsBio revisits how α-synuclein drives Lewy bodies formation. We propose a new concept: 👉 Multifactorial Random Disorder Model to explain how diverse biomolecules are sequestered during LB formation. rdcu.be/eYtHr #ParkinsonsDisease #LewyBodies #AlphaSynuclein #Neurodegeneration #Biomarkers #DrugDiscovery
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My student, @Jos_sneha, is capturing a beautiful illustration of how α-synuclein drives Lewy body formation. Science meets art—perfectly! #ParkinsonsDisease #LewyBodies #AlphaSynuclein #Neurodegeneration
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I am thankful to my team, @Jos_Sneha and Niharika Shivanandaswamy, and to our collaborators, @NathSangeeta, Neelakandan’s team at @DBT_inStem, and Deepak Sharma at @CSIR_IMTECH. We are grateful to @ANRFIndia and @NIMHANS_BLR for the support that made this work possible.
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🧠 Lewy bodies—the pathological hallmark of #Synucleinopathies How does α-synuclein sequester diverse biomolecules within the crowded cellular environment to drive Lewy body formation? #AlphaSynuclein #LewyBodies #ParkinsonsDisease #Neurodegeneration #NIMHANS
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A proud moment today—my first PhD student, Ms. @Jos_sneha, submitted her thesis. She completed her PhD with 9 publications, including 2 papers in Communications Biology (Nature Portfolio), J Mol Biol, and Protein Science. Congratulations, Sneha! 🎓👏 #PhD #Mentorship #StructuralBiology #Neuroscience #NIMHANS
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#alphaSynuclein #LewyBody #ParkinsonsResearch #Neuroscience #NIMHANS
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NIMHANS PhD applications are now open! Our Chromatin Structural Biology Lab at NIMHANS is looking for highly motivated candidates with CSIR/UGC/ICMR/DBT fellowships (or equivalent) for a PhD position to work on key proteins associated with Alzheimer’s and Parkinson’s disease. Interested candidates may reach out or apply through the NIMHANS PhD portal. Please share with potential applicants. @NIMHANS_BLR
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Proud moment for @SivaramanLab!. My student @Jos_sneha won the Best Paper Award at the Indian Academy of Neuroscience 2025 meeting at @RGCB_Trivandrum for our recent paper on the nuclear role of alpha-synuclein associated with Parkinson's disease doi.org/10.1038/s42003-025-0…. Thanks to @ANRFIndia and @NIMHANS_BLR
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I am pleased to share that I have been promoted to Additional Professor in the Department of Biophysics at #NIMHANS. I am grateful to my mentors, students, colleagues & family for their constant support.
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Sivaraman Padavattan retweeted
Giriraj Sahu@gsahu_iisc
13 Jun 2025
We are looking for Research Assistant Fellows possessing strong research interests and the ability to work in a team and collaborative environment. @ICMRDELHI @DBTIndia @iiscbangalore @MBU #research #ProjectAssistant Please spread the word
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I am excited to share our latest work on nuclear #αSynuclein, now published in @CommsBio rdcu.be/eljiL Our study unveiled, for the first time, #αSynuclein physiological function in the nucleus, shedding light on a decades-old question in this field. @NIMHANS_BLR
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Grateful to my team @Jos_Sneha and @ArchanaKambaru and collaborators @NathSangeeta and Neelakandan’s team at @inSTEM and funding agency SERB (@ANRF) for their support! #Parkinsons #AlphaSynuclein #Chromatin #Neuroscience @NIMHANS_BLR
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A reviewer commented: "α-Synuclein physiological and non-physiological roles have been under debate for decades. The current manuscript is a very important contribution to this long-standing conundrum, opening new avenues of thinking and new experiments to be done."
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Just returned from #Synuclein2025 — an inspiring meeting showcasing the latest advances in synuclein biology. Proud to have presented our recent work on the nuclear physiological role of #αSynuclein. #ParkinsonsResearch @NIMHANS_BLR With: Nagendran Ramalingam, Ulf Dettmer
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Thrilled to share that our latest work on nuclear #αsynuclein has been accepted for publication! Stay tuned for insights into its role in chromatin dynamics and implications for Parkinson’s disease. #AlphaSynuclein #Chromatin #Parkinsons #Neurodegeneration @NIMHANS_BLR
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The National Institute of Mental Health and Neurosciences (@NIMHANS_BLR), an Institute of National Importance, Bengaluru, invites applications for various postgraduate, PhD, and post-doctoral programs for the 2025-2026 academic year.
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Our Biophysics Department at @NIMHANS_BLR offers: Two fully funded PhD positions. Interested candidates, please visit the NIMHANS admission portal for details and application procedures.
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Opening for one PhD position in @SivaramanLab to work on neurodegenerative diseases (Parkinson’s disease, Alzheimer’s disease). Candidates with CSIR/DBT/ICMR-JRF are encouraged to apply via the NIMHANS admission portal.
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