Soldati-Favre lab, interested in all aspects of Toxoplasma biology (run by PhDs and PostDocs) ๐จ๐ญ๐ซ๐ท ๐จ๐ณ ๐น๐ผ ๐ช๐ธ ๐ฉ๐ช ๐ธ๐ฐ ๐ฎ๐น ๐จ๐ด ๐ญ๐บ ๐ฑ๐ง ๐จ๐ฆ
Joined November 2019
- Tweets 275
- Following 174
- Followers 1,377
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64 Photos and videos
Feb 13
๐จNew paper from the lab!๐จ
As everyone, Toxoplasma needs to feed its daughter cell for their proper development ๐ซ๐ Here, we describe the first transporter that regulates lipid homeostasis of the daughter cell alveoli. @SanchezSyrian
Find more here ๐
journals.plos.org/plospathogโฆ
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๐จNew paper from the lab! ๐จ
What happens during PCR biogenesis? Why is there a non-functional myosin in the PCRs? ๐ฌ๐
This and much more in the bioRxiv preprint ๐
biorxiv.org/content/10.64898โฆ
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9 Dec 2025
New paper from the lab! Great collaborative work to show the tethering of the conoid ๐ฌ๐งซ Congrats to all the authors involved! ๐
journals.plos.org/plosbiologโฆ
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3 Mar 2025
๐จNew paper out! ๐จ
The apicoplast is an essential plastid retaining many crucial metabolic pathways ๐ฆ ๐ญ However, bypassing all of them makes the apicoplast dispensable!
nature.com/articles/s41467-0โฆ
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3 Mar 2025
This parasite can be continuously cultured, offering a valuable tool for apicoplast research and drug discovery! ๐๐ฌ
Congrats to all the authors involved for this amazing piece of work! ๐๐
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Soldati Lab retweeted
3 Feb 2025
Excited to see our paper published in MBOC! ๐ Our research explores a glyoxalase-like protein in the apicoplast, crucial for Toxoplasma growth and organelle homeostasis maintenance. Huge thanks to the newly promoted Research Director @s_besteiro๐โโ๏ธ
doi.org/10.1091/mbc.E24-09-0โฆ
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Soldati Lab retweeted
20 Jan 2025
Our structure-function analysis of the #Toxoplasma #mitoribosome reveals a novel role for poly A tails and repurposed protein domains in mending tens of rRNA pieces into a functioning ribosome
nature.com/articles/s41467-0โฆ
@BIOTECH_UH @wellcometrust @UofGSii @UofGMVLS @shikha_tweets
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Soldati Lab retweeted
17 Dec 2024
It's a great pleasure to share our latest collaborative work detailing the composition and structure of the highly rRNA-fragmented mitoribosome from Apicomplexa, such as Plasmodium falciparum and Toxoplasma gondii, now out in @NatureComms
rdcu.be/d3R8C
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17 Dec 2024
Mitochondria are the powerhouse of the cell, producing essential energy for life ๐ญโ๏ธ. To synthesize the proteins for this process, mitochondria have mitoribosomes. But, how do the mitoribosomes from Alveolates assemble? ๐งต
nature.com/articles/s41467-0โฆ
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17 Dec 2024
These findings highlight a novel adaptation shared between the Alveolata, by which transcription factors evolved into RNA-binding proteins. Targeting this unique mitoribosome assembly machinery could open new possibilities to treat diseases such as malaria and toxoplasmosis. ๐ฆ ๐
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17 Dec 2024
Last but not least, big congrats to @Hashemyaser4 @OscarVadas and all the others authors involved! ๐๐๐โโฌ
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29 Nov 2024
Christmas is coming โ๏ธ, and in Switzerland this means... fondue! ๐ซ Enjoying tons of cheese with #Brochetlab and @AmandineGuerin5 lab ๐งโ๏ธ๐ฌ
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Soldati Lab retweeted
How does #Toxoplasma gondii move? @unige_en scientists reveal apical polar ring & conoid as key players controlling actin flow, crucial for motility & invasion
Full bit.ly/4i33Tk3
Summary bit.ly/4i9Zg7V
By @Romzouz1 & Bingjian Ren @SoldatiLabToxo @MIMOL_UNIGE
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8 Nov 2024
๐จ New publication out: Architecture of the Toxoplasma gondii apical polar ring and its role in gliding motility and invasion ๐งซ๐โโฌ
Read more
pnas.org/doi/10.1073/pnas.24โฆ
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8 Nov 2024
In this article, a repertoire of apical polar ring proteins was studied and assigned to the different APR layers.
Among them, APR2 contributed to parasite's motility and invasion and its depletion caused destabilisation of the APR middle layer and F-actin leakage to the cytosol.
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8 Nov 2024
Thanks to the wonderful collaboration with @yiweichang ๐ค and congratulations to @Bingjian_Ren, @Romzouz1 and all the authors involved! ๐ฌโ๏ธ๐
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5 Sep 2024
Congrats to @SanchezSyrian and all the authors involved in the paper describing a novel protein involved in apicoplast homeostasis and parasite growth! ๐๐ฆ ๐โโฌ
biorxiv.org/content/10.1101/โฆ
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Soldati Lab retweeted
30 Aug 2024
RNG2 tethers the conoid to the apical polar ring in Toxoplasma gondii: a key mechanism in parasite motility and invasion dlvr.it/TCY679
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