Molecular Systems Neuroscience @ Weizmann

Joined November 2017
55 Photos and videos
Ivo Spiegel retweeted
Can someone start a journal called “Cell Atlases” so that the rest of the journals can go back to publishing interesting things?
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Another year of @Spiegel_Lab, another Shavuot cheesecake for the lab 😋
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Interesting Perspective by @ItaiYanai in @Nature on the role of GRNs & AP-1 in regulating permanent cellular adaptations ("cellular learning"?) of cancer cells to new environmental stimuli nature.com/articles/s41586-0… 1/3

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Given the importance of AP-1 and experience-induced transcription in the brain, I wonder whether & how these or similar mechanisms may be at play in different forms of brain plasticity & learning (e.g., critical period plasticity, or “one-shot” vs gradual learning) 2/3
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In short, lots of room for exciting discoveries 🙂 In addition to the available (amazing!) tools for (epi-)genomics, cracking the combinatorial code of AP-1 will probably require new technologies e.g. for single-cell/-nucleus (phopsho-)proteomics. 3/3
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Pls RT: Join us at the 1st-ever conference on “Experience-Regulated Transcription”! Oct 5-7 2026 in Florida, with a fantastic line-up, @MEGNeuro @NadavAhituv @JasonSynaptic @BarcoLab @DayLabUAB @Gabel_Lab @apombo1 @SenguptaLab @Ryohei_Neuro @CreminsLab tinyurl.com/mr2zpzdb
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And did I mention that this conference is under the auspices of @FASEBorg (🙏🙏🙏) and organized by Anne West, @RamenNSaha, and yours truly? And that @FrankieDHeyward will be there as well? So, don’t hesitate, sign up & join us, the registration is open 🙂
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And of course @IvaZovkic will be there as well🙂
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Also there will be @RWTsien @AmaxTweets @DiscoverURBrain @Serenadudette @angalus_d @Yingxilinlab, Hilmar Bading, Yukiko Gotoh, Frankie Hayward, Tea-Kyung Kim, Ram Mandabushi, Filippo Riji – and you?! Looking forward to seeing you all in Florida!
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Ivo Spiegel retweeted
Given these uncertain times, it’s time to reconnect and come together to discuss all things synapse at grc.org/synaptic-transmissio…. Join us in Italy for an outstanding lineup of speakers! We still have open slots for short talks and late-breaking findings. @of_sagol @SamYoungLab
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🚨Paper Alert🚨 After 4(!!!) years of revisions, the amazing @KetiCohen & team pushed out this beauty💪 Unlike what the textbooks say, V1 binocularity is not fixed: at high arousal, binocularity decreases while the strength of peripheral vision increases. nature.com/articles/s41467-0…
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Ivo Spiegel retweeted
Excited about this project combining 2-photon imaging & spatial transcriptomics: biorxiv.org/content/10.64898… Lead scientist: @jason_hc_yong Collaborator: @erdem___varol Video: memorylongevity.org Website: memorylongevity.org/merscope…

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Ivo Spiegel retweeted
Our new paper with @attila_losonczy @Spiegel_Lab out now!
Online now: 2P-NucTag: On-demand phototagging for molecular analysis of functionally identified cortical neurons dlvr.it/TRs45P
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Paper Alert🚨🚨🚨 Want to analyze your in vivo functionally characterized neurons with RNA-seq, spatial transcriptomics, immunolabeling, or ex vivo patch-clamp? Use our awesome 2P-NucTag approach! Great collab w/ @attila_losonczy & team, congrats to all. sciencedirect.com/science/ar…

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לקח כמעט 35 שנים שאני בארץ עד שיצא לי סוף סוף לראות את שלמה ארצי בהופעה חיה. אתמול זה קרה (בBarby), היה מעולה, פרפורמר אדיר, תודה!
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Ivo Spiegel retweeted
Our lab is hoping to hire a long-term lab manager / research associate to help with admin tasks and neuroscience experiments (3-year minimum commitment). Please RT! bilh.wd1.myworkdayjobs.com/E…

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Please RT: SAVE THE DATE, this gonna be epic! The first-ever in-person conference on Experience-Dependent Transcription on October 5-7 2026 in Melbourne, FL. Fantastic speakers, ECR-support, & plenty more (events.faseb.org/event/neuro…). See y’all there! #NeuroExpSRC
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And who says that only troubles come in droves??? A ceasefire, the return of the (alive) hostages, a fat grant, tenure, a new grad stud joining the lab, a paper that got decent reviews, some excellent private news... I feel on a roll, let the good news keep coming!
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Tenure! Been dreamin’ of this for a long time, and now it feels a bit like the one figure that summarizes years of experiments, only on steroids 😀 A GIANT THANK YOU to all my lab members, trainees, mentors, colleagues, friends, and especially my family who made this possible.
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