@Staph_papers profile picture
Staph papers @Staph_papers

Tweeting papers found on #PubMed/#bioRxiv/#medRxiv about S. aureus and other staphylococcal species #Staph

Joined April 2020
  • Tweets 13,258
  • Following 0
  • Followers 1,198
Photos and videos
Reduced efficacy of an anti-toxin vaccine from senescence-driven attenuation of toxin virulence ift.tt/R3cNWHZ

Reduced efficacy of an anti-toxin vaccine from senescence-driven attenuation of toxin virulence -...

It remains unclear why vaccines targeting prominent microbial virulence factors often fail in clinical trials. Because microbial virulence depends on interaction with the host immune system, we...

pubmed.ncbi.nlm.nih.gov
50
Engineering Nano-Antibiotics for Accelerating Wound Healing in Drug-Resistant Bacterial Infections ift.tt/9jWKzLa

Engineering Nano-Antibiotics for Accelerating Wound Healing in Drug-Resistant Bacterial Infections...

Plenty of nano-antimicrobial materials have been developed successively, aiming to address severe clinical challenges such as wound healing disorders and high postoperative mortality rates caused by...

pubmed.ncbi.nlm.nih.gov
27
Getting It Right the Second Time: How Can we Optimize First-Generation Cephalosporin Dosing for Skin and Soft Tissue Infections in the 21st Century? ift.tt/zn53G1g

Getting It Right the Second Time: How Can we Optimize First-Generation Cephalosporin Dosing for...

Optimal cephalexin and cefadroxil dosing for skin and soft tissue infections (SSTIs) is unclear. We summarize clinical and pharmacokinetic/pharmacodynamic (PK/PD) data that compare dosing strategies...

pubmed.ncbi.nlm.nih.gov
20
The toxic effects of α-hemolysin and β-hemolysin produced by Staphylococcus aureus ift.tt/bYsVw5e

The toxic effects of α-hemolysin and β-hemolysin produced by Staphylococcus aureus - PubMed

Staphylococcus aureus (S. aureus) is a Gram-positive bacterium widely distributed in nature, which can cause skin and soft tissue infections, sepsis, pneumonia and other invasive diseases. In recent...

pubmed.ncbi.nlm.nih.gov
30
A wireless battery-free intelligent system for in situ bacterial virulence detection and advanced wound therapy ift.tt/Q8z2aH1

A wireless battery-free intelligent system for in situ bacterial virulence detection and advanced...

Here, we present an intelligent wound patch system (iWPS) that integrates an organic electrochemical transistor (OECT) sensor, a DNase-responsive DNA hydrogel preloaded with cefazolin sodium (CS),...

pubmed.ncbi.nlm.nih.gov
21
PLGA-PEG Nano-Adjuvant-Delivered ClfA Vaccine Elicits IL-17A-Mediated Neutrophil Activation to Confer Complete Protection Against Methicillin-Resistant Staphylococcus aureus ift.tt/1mQCgoz

PLGA-PEG Nano-Adjuvant-Delivered ClfA Vaccine Elicits IL-17A-Mediated Neutrophil Activation to...

This study demonstrates that the PLGA-PEG nanoparticle-based rClfA nano-vaccine can effectively redirect immune responses toward protective Th1/Th17 immunity and robustly protect against lethal S....

pubmed.ncbi.nlm.nih.gov
1
46
Phenotypic and genotypic characterization of Staphylococcus aureus, including MRSA and PVL-positive isolates, in Egyptian fruit bats ift.tt/PJpA3to

Phenotypic and genotypic characterization of Staphylococcus aureus, including MRSA and PVL-positive...

This study provides evidence of S. aureus carriage in Egyptian fruit bats, including MRSA and PVL-positive isolates, some of which were multidrug-resistant. These findings suggest that bats may serve...

pubmed.ncbi.nlm.nih.gov
46
Staphylococcus aureus With Reduced Vancomycin Susceptibility: Diagnostic Challenges in Clinical Settings ift.tt/RG1yvLN

Staphylococcus aureus With Reduced Vancomycin Susceptibility: Diagnostic Challenges in Clinical...

Vancomycin-intermediate Staphylococcus aureus (VISA) and vancomycin-resistant S. aureus (VRSA) have become significant challenges in treating staphylococcal infections, especially in areas where...

pubmed.ncbi.nlm.nih.gov
2
94
Clinical Rel mutations that increase basal (p)ppGpp promote conjugal transfer of staphylococcal resistance plasmids ift.tt/EC8VIRn

Clinical Rel mutations that increase basal (p)ppGpp promote conjugal transfer of staphylococcal...

Conjugative transfer of plasmids represents a major route through which antibiotic resistance genes are spread. In the case of the prevalent and deadly pathogen Staphylococcus aureus, more than 90%...

pubmed.ncbi.nlm.nih.gov
1
1
68
Extracellular wax ester biosynthesis by staphylococcal lipases detoxifies skin fatty acids and shapes interspecies competition ift.tt/EOIglMd

Extracellular wax ester biosynthesis by staphylococcal lipases detoxifies skin fatty acids and...

To maintain its barrier function, human skin requires lipids, including cholesterol, ceramides, free fatty acids, and wax esters. In contrast to other skin lipids, wax esters remain largely unexplo...

pubmed.ncbi.nlm.nih.gov
41
Mortality associated with healthcare-associated Staphylococcus aureus bacteraemia in Aotearoa New Zealand ift.tt/ReqLgAx

Mortality associated with healthcare-associated Staphylococcus aureus bacteraemia in Aotearoa New...

The 30- and 90-day all-cause mortality associated with HA-SAB is high. The most common sources are vascular access devices. The use of a "care bundle" incorporating proven interventions, applied...

pubmed.ncbi.nlm.nih.gov
1
27
Urogenital infections select for reduced ability to grow in a low-iron environment and reduced blood survival for Staphylococcus aureus ift.tt/r1HqjQR

Urogenital infections select for reduced ability to grow in a low-iron environment and reduced...

Immunity through nutrient sequestration is one of the means by which a host can protect itself from infection. As a consequence, many micro-organisms have evolved strategies to overcome this,...

pubmed.ncbi.nlm.nih.gov
31
Phenotype and Genotype of Staphylococcus aureus Isolated from the Nostrils of Elderly Adults in the Valparaíso Region, Chile, from June 2019 to January 2020 ift.tt/fBcMVQT

[Phenotype and Genotype of Staphylococcus aureus Isolated from the Nostrils of Elderly Adults in...

Nasal carriage of S. aureus was similar to studies of the general population and the same age group from Latin America and Europe; however, MRSA carriage was higher. Strains from older adults...

pubmed.ncbi.nlm.nih.gov
34
In Vivo Assessment of Antimicrobial Potential of Synthetic ANLP-V3 Peptide for the Treatment of Mastitis in a Mouse Model ift.tt/wSgcGkW

In Vivo Assessment of Antimicrobial Potential of Synthetic ANLP-V3 Peptide for the Treatment of...

Therapeutic intervention in bovine mastitis faces significant challenges, primarily due to antimicrobial resistance (AMR) and formation of biofilms by etiological agents. Staphylococcus aureus (S....

pubmed.ncbi.nlm.nih.gov
35
Mechanisms underlying pyogenic bacterial infections of the skin ift.tt/k7aXSU2

Mechanisms underlying pyogenic bacterial infections of the skin - PubMed

Pyogenic skin infections are commonly caused by Staphylococcus aureus (SA), Streptococcus pyogenes (GAS), and Pseudomonas aeruginosa (PA). Although these pathogens differ markedly in phylogeny, cell...

pubmed.ncbi.nlm.nih.gov
30
A dual functional theranostic microneedle patch for immunomodulation and real time monitoring in diabetic wound therapy ift.tt/mOkwgjM

A dual functional theranostic microneedle patch for immunomodulation and real time monitoring in...

This work pioneers a theranostic platform that integrates real-time diagnostic, controlled catalytic therapy, and immunomodulatory therapy, providing a viable approach to the autonomous management of...

pubmed.ncbi.nlm.nih.gov
22
Antibacterial activity and mechanism of the antiparasitic drug resorantel against Staphylococcus epidermidis ift.tt/CIWNR7S

[Antibacterial activity and mechanism of the antiparasitic drug resorantel against Staphylococcus...

Resorantel exhibits both in vitro and in vivo antibacterial activity against S. epidermidis. Its antibacterial mechanism involves disruption of bacterial membrane integrity and proton motive force,...

pubmed.ncbi.nlm.nih.gov
27
Molecular Diversity and Comparison of Staphylococcal Cassette Chromosome mec Element in Hospital- and Community-Associated Methicillin-Resistant Staphylococcus aureus From Pakistan ift.tt/4K3rjRH

Molecular Diversity and Comparison of Staphylococcal Cassette Chromosome mec Element in Hospital-...

Prevalence of MRSA and the types of SCCmec are on the rise. Because of the high prevalence of multiresistant type III cassettes, antibiotic resistance is also increasing. The high occurrence of...

pubmed.ncbi.nlm.nih.gov
34
MDRO infections in the NICU- The international perspective ift.tt/tNGIghk

MDRO infections in the NICU- The international perspective - PubMed

Neonatal sepsis due to Multidrug resistant organisms (MDRO) is a huge burden in resource limited settings of South Asia and Africa. The epidemiology, risk factors, diagnostic and management challen...

pubmed.ncbi.nlm.nih.gov
25
Using biofilm-targeting local antibiotics to treat recalcitrant medical device-associated infections: driveline infection as a model ift.tt/7UgFGEq

Using biofilm-targeting local antibiotics to treat recalcitrant medical device-associated infecti...

Driveline infection, exemplifying medical device-associated infection, is a difficult-to-treat complication of ventricular assist device implantation in which biofilm formation underlies both...

pubmed.ncbi.nlm.nih.gov
40
Load more