A SAGE Open Access journal | Publishing high-quality articles in infectious disease | Editor-in-Chief @andhen25 | IF 3.8
Joined February 2020
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Geospatial targeting of TB screening in Uganda reduced screening volume by 92%, increased TB yield by 10%, and cut costs by >90%. Surveillance data can help find more TB with fewer resources
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Neonatal sepsis remains alarmingly common in Ethiopia: pooled prevalence 29.9%, with 66.2% multidrug resistance. Klebsiella pneumoniae and E. coli predominated, showing high resistance to first-line antibiotics. journals.sagepub.com/doi/ful…
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Adult HBV vaccination decisions are shaped not only by access barriers, but also by culturally embedded beliefs. Context-sensitive education provider recommendations are key
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Do all patients with CIED infection need prolonged antibiotics? In this cohort, ≤2 weeks of therapy AFTER device extra extraction had similar mortality and recurrence rates compared with longer courses after complete device removal.
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Late-onset CMV pneumonia can occur even 1 year after auto-HSCT, particularly in patients with profound CD4 lymphopenia. This case highlights the value of immune-guided surveillance and BALF mNGS in diagnosing complex infections in immunocompromised hosts.journals.sagepub.com/doi/ful…
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Scrofuloderma can mimic hidradenitis suppurativa and other chronic skin diseases. This case highlights the need to consider TB in atypical recurrent skin lesions
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Among graduating healthcare students at Debre Tabor University:
💊 68% bought antibiotics without a prescription
🧠 Only 32.5% recognized antimicrobial stewardship (AMS)
Knowledge alone isn’t enough
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In a cohort from Gulu City, 45.4% experienced viral non-suppression, driven by poor ART adherence, delayed HIV disclosure, advanced disease, young age, and economic hardship.
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New systematic review & meta-analysis in SSA HCWs shows moderate AMR knowledge (65%) and attitudes (69%), but weaker practices (54%), with a clear knowledge–practice gap—most evident among doctors (knowledge 65%, practice 43%).
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Meet our Biostatistical Editor, Theophilus I. Emeto @ti_Emeto 📊
Featured today ! 👇
#InfectiousDiseases #Biostatistics #EditorialSpotlight
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✨ Introducing our Editorial Spotlight Series
👀 Meet the people behind the science
What motivates them 🚀 What inspires them 🌱
What brings them joy 🎶Because great work starts with real people ❤️Stay tuned as we highlight our team!
#EditorialSpotlight
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TB treatment is evolving—but persistence remains a major barrier. New evidence shows macrophage metabolism and redox state shape intracellular drug tolerance in Mtb. Host-directed strategies may enhance antibiotic efficacy and help shorten therapy ⏳
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Case report: a young patient with years of “chronic lung disease” ultimately diagnosed with aggressive HTLV-1 driven lymphoma-fatal within weeks. Early biopsy T-cell panel (CD4 CD25 with CD7 loss) should trigger HTLV-1 testing, regardless of geography.
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CKD and UTIs form a vicious cycle: kidney dysfunction increases infection risk ; while recurrent UTIs accelerate renal decline. Breaking this loop demands early CKD detection, antimicrobial stewardship & non-antibiotic prevention strategies.
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Neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) are valuable, readily available markers for gauging severity in community-acquired pneumonia 🦠📊
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Prospective study (Ukraine/Moldova/Spain, n=287): mfloDx™ MDR-TB assay achieved Se 100% / Sp 98.7% for INH RIF resistance vs culture DST. Caveat: 35% inconclusive results. Potential role as rapid screening tool.
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Does EV-D68 amplify TB immunopathology?
Case series suggests coinfection may worsen lung inflammation, with clinical response seen after corticosteroid escalation.
A reminder to consider viral triggers in atypical TB courses.
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Arboviruses don’t act in isolation 🦟 Chikungunya and Zika spread where structural vulnerabilities persist—limited surveillance, inequity, and inadequate sanitation. Future resilience depends on integrating social and biological surveillance systems 🧬.journals.sagepub.com/doi/10.…
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Diagnosing invasive mold infections 🧫 in immunocompromised patients remains difficult.NGS 🧬 offers noninvasive, actionable insights-identifying missed infections and guiding therapy in over half of cases.
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Malaria 🦟 soil-transmitted helminths 🪱 often co-infect young children in Nigeria, driving early red cell changes 🩸 before overt anaemia. Host factors esp haemoglobin genotype 🧬matter more than parasite load. journals.sagepub.com/doi/10.…
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