Transplantation Direct is an open access journal for international transplantation content. It is Transplantation's companion journal.

Joined October 2014
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The June issue of @TXPDirect is jam-packed with useful information for our diverse international transplantation readership. We welcome you to visit our Transplantation Direct website for full details in open-access. #OpenAccess #TransplantTwitter bit.ly/TXDissue
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CTLA4-Ig combined with anti-IL-6/IL-6R therapy improved graft function, resolved CNI toxicity, reduced donor-specific antibodies, and promoted a more regulatory immune profile. #TXPforAll #KidneyTransplantation #OpenAccess tinyurl.com/37fpzavf
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Should age or cancer history determine kidney transplant access is addressed in this paper by Lim et al. #TXPforAll #Transplantation #OpenAccess tinyurl.com/4upud6vk
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Living kidney donors reported improving pain control with very limited opioid use by 2 weeks after donation. #TXPforAll #Transplantation #OpenAccess tinyurl.com/2fhm7f6b
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Pacemakers may offer a safer pacing option for solid organ transplant recipients at high infection risk. Early experience with the Aveir LP platform showed successful implantation, stable performance with no device-related infections during follow-up. tinyurl.com/yck2mnet
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This study by Wang et al. shows that pediatric donor kidneys can successfully adapt and grow after transplantation into pediatric recipients, supporting strong long-term function and reinforcing the feasibility of pediatric-to-pediatric kidney tinyurl.com/47797cac
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Can normothermic machine perfusion (NMP) delay acute rejection in vascularized composite allotransplantation is addressed in this research paper by von Reiterdank et al. #TXPforAll #Transplantation #OpenAccess tinyurl.com/mr22ada4
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NMP during liver preservation in SLK transplantation was linked to better kidney outcomes vs SCS: lower functional DGF, improved early eGFR, and reduced dialysis at 6 months. #TXPforAll #Transplantation tinyurl.com/5n97d5u3
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Pediatric-to-pediatric kidney transplants show strong adaptability: smaller donor kidneys grow rapidly—reaching age-appropriate size within ~6 months—and support good function, reinforcing this strategy as safe and effective. #TXPforAll #OpenAccess tinyurl.com/47797cac
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Genetic testing is reshaping kidney transplant evaluation: over one-third of candidates had a genetic diagnosis often clarifying cause and guiding donor decisions. #TXPforAll #OpenAccess #Transplantation tinyurl.com/3zuejwwc
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This paper by @nerecugo et shows that a slow-release form of necrostatin-1 using PLGA microparticles helps to protect islets under stress preserving insulin function and reducing inflammation.#TXPforAll #Transplantation #OpenAccess tinyurl.com/3dp4p3by
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New SLK/KAL allocation rules show promising results: few patients needed SLK, many recovered kidney function after liver transplant alone, and outcomes after SLK and KAL were similar. #TXPforAll #Transplantation #OpenAccess tinyurl.com/yzz3k9uz
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The May issue of @TXPDirect is jam-packed with useful information for our diverse international transplantation readership. We welcome you to visit our Transplantation Direct website for full details in open-access. #OpenAccess #TransplantTwitter bit.ly/TXDissue
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Research by Tector and coworkers shows that pig SLA-12 behaves like classical class I molecules and can bind peptides, form surface complexes, and attract human antibodies—suggesting it may be an additional xenoantigen to consider in xenotransplantation. tinyurl.com/t8u6f632
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NMP may not fully rescue livers after prolonged cold ischemia—longer storage led to poorer recovery or increased injury in a pig DCD model. #TXPforAll #Transplantation #OpenAccess tinyurl.com/4cprrnkz
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High Hb (concentrated blood) impaired cardiac function and increased hemolysis, while whole blood and plasma better preserved heart performance over time. 👉 Diluting Hb may be key to optimizing heart preservation during ex situ heart perfusion. tinyurl.com/4zhwz8kk
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3 kidney transplants between identical twins performed with no immunosuppression ✅ Up to 22 years follow-up ✅ Excellent graft function ✅ No rejection episodes Supports immunosuppression-free transplant as a safe, effective option in monozygotic twins. tinyurl.com/5x67yx7d
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🚨 Kidney care gap: In South Africa, 79% of patients needing KRT received no treatment and were presumed dead. Access to dialysis/transplant favored younger, healthier, wealthier patients.💡 Transplant saves lives but capacity limits decide who gets it. tinyurl.com/3pujenpx
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Retroperitoneoscopic nephrectomy . • Similar surgery time, blood loss & kidney size • BUT muscle damage was dramatically lower with RN • Better long-term cosmetic outcomes. RN kidney transplant is safe, less invasive, and kinder to the body. tinyurl.com/3yn8bada
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