🌍 open science movement to develop by 2035 pharmacological tools for all human proteins; tinyurl.com/t2035 & tinyurl.com/t2035utube
Joined August 2021
- Tweets 492
- Following 390
- Followers 549
- Likes 693
33 Photos and videos
Target 2035 retweeted
16 Dec 2024
#MAINFRAME is launching! This international, #OpenScience Network brings #MachineLearning & #compchem scientists together to create open-source algorithms & benchmarks for tackling real-world challenges in #DrugDiscovery. Join us: aircheck.ai/mainframe
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13 Dec 2024
#MAINFRAME is an #OpenScience Network, supported by Target2035 & ultra-large-scale experimental screening data, brings #MachineLearning & #compchem scientists together to create open-source algorithms & benchmarks tackling #DrugDiscovery challenges.
aircheck.ai/mainframe
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Target 2035 retweeted
New episode for our Target 2035 Podcast Series 🎧
@MilkaKostic talks with @aledmedwards to unpack his journey from a traditional research scientist to a passionate open science advocate.
Listen here: bit.ly/3AZQkBm
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Target 2035 retweeted
A fully open framework for DEL-ML hit discovery. We replace explicit DEL compound structures with ML-ready chemical fingerprints, enabling the broad scientific community to advance DEL-ML models and refine discovery methods. All data available on AIRCHECK.
chemrxiv.org/engage/chemrxiv…
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Target 2035 retweeted
A well anticipated overview highlighting the first CACHE challenge, which brought together 23 research teams from 10 countries to collectively predict 1,955 compounds targeting LRRK2-a protein linked to #ParkinsonsDisease.
pubs.acs.org/doi/10.1021/acs…
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Target 2035 retweeted
21 Nov 2024
🚨 New publication alert! 🚨
Our latest update on the Chemical Probes Portal is live! 🎉
📜 Read the paper: doi.org/10.1093/nar/gkae1062
🔍 Learn about our expanded content improved functionality in the 2024 Nucleic Acids Research Database Issue.
#ChemicalProbes #BiomedicalResearch
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Target 2035 retweeted
5 Nov 2024
📢RSC Medicinal Chemistry is delighted to announce our newest Associate Editor, Dr Susanne Müller-Knapp from @goetheuni!
📰Read our blog for more about Susanne: blogs.rsc.org/md/2024/10/21/…
👀Submit to her today: mc.manuscriptcentral.com/mcc
@Chemical_probes @thesgconline
ALT RSC Medicinal Chemistry New Associate Editor, Susanne Müller-Knapp, promotional slide.
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12 Nov 2024
Just Launched! Episode 1 of the Target 2035 Podcast Series🎧 In the debut episode, @LabScribbles welcomes @CherylArrowsmi1, a leading scientist in chemical biology and one of the initiators of Target 2035.
podcasters.spotify.com/pod/s…
#Target2035 #OpenScience #DrugDiscovery
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25 Oct 2024
🎙️ The Target 2035 podcast series is officially LIVE!
In our pilot episode, meet our hosts - @MilkaKostic, @LabScribbles and Opher Gileadi who share their personal motivations for joining the Target 2035 initiative.
Tune in to the pilot episode now! podcasters.spotify.com/pod/s… 🎧
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16 Oct 2024
🎙️ Get ready... Something BIG is coming from Target 2035! What if the future of drug discovery could be unlocked by listening in? @LabScribbles, @MilkaKostic and Opher Gileadi got something brewing, and trust us- you won’t want to miss it!
#Target2035, #OpenScience, #ComingSoon
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Target 2035 retweeted
28 May 2024
The short history of NSD2 degraders has been a little fuzzy with some odd mechanisms of action so far, but this one seems a little cleaner and more potent than its forebears.
pubs.acs.org/doi/10.1021/acs…
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Target 2035 retweeted
27 May 2024
This is a terrific and comprehensive review on molecular glues from the Arkin lab. Open access too.
cell.com/cell-chemical-biolo…
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28 May 2024
Our ASMS platform is now officially up and running! @HalabelianLab and Hui Peng, with the support of the @InnovationCA, have completed the first round of ASMS screenings for 8 proteins in just 2 weeks, including thorough hit verification.
Stay tuned for more exciting data!
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Target 2035 retweeted
6 May 2024
Nice work from Gray and @fischerlab1 labs on combinatorial libraries for CRBN molecular glue discovery that yielded a WEE1 degrader. biorxiv.org/content/10.1101/…
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Target 2035 retweeted
11 Mar 2024
Wow!! Congratulations @BShoichet and others.
11 Mar 2024
Structure-based discovery of CFTR potentiators and inhibitors | bioRxiv
biorxiv.org/content/10.1101/…
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11 Mar 2024
Need a #chemicalprobe?
@chemical_probes has reached 1000 chemical tools that have been reviewed by #drugdiscovery experts.
Kudos to @Chemical_probes for reaching 1,000 compounds! A great collaboration with @target2035 to expedite chemical probe discovery.
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15 Jan 2024
#AstraZeneca publishes on the challenges and impact on developing #highthroughput #thermalshift based #drugdiscovery
High-throughput differential scanning fluorimetry (DSF) and cellular t... sciencedirect.com/science/ar…
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Target 2035 retweeted
Stefan Knapp and Susanne Muller talk about how different stakeholders can contribute to high-quality research using small molecule tools.
nature.com/articles/s41589-0…
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Target 2035 retweeted
We are happy to share that @target2035 will be featured in the upcoming @ChemBioSociety 2023 with a scientific session chaired by @CherylArrowsmi1. Among the speakers will be our very own @mattschap and Serah Kimani from @HalabelianLab.
More details: chemical-biology.org/
🔬 Join us at #ICBS2023 for a special scientific session featuring @target2035, a global open science movement with to develop a modulator for every protein in the human proteome by 2035. Sponsored by @EUbOPEN. More details: chemical-biology.org
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19 Sep 2023
A recent review by Edelris and AstraZeneca on "Affinity selection mass spectrometry speeding drug discovery" pubmed.ncbi.nlm.nih.gov/3766…
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