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Our #EUbOPEN consortium of 22 partners will work together on a 5 year 66M€ @IMI_JU
project @EUbOPEN
to generate open-access chemogenomics compounds and chemical probes! Find out more here: lnkd.in/dHTJ2kc #OpenScience
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@EUbOPEN partner @AlessioCiulli, pioneers a molecule that targets a previously "undruggable" protein class! By ingeniously masking the molecule, it can enter cells paving the way for innovative disease treatments.
nature.com/articles/s41467-0…
@IMI @UoDCeTPD
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EUbOPEN retweeted
In the last #20yearsSGC, we're thrilled to be part of the @EUbOPEN consortium, an endeavor dedicated to developing high-quality chemical tool compounds for 1,000 proteins. Over the past 3 years, our collective efforts have yielded remarkable achievements.
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EUbOPEN retweeted
The 2nd @EUbOPEN annual meeting was successfully held earlier this week. Among affiliated partners, SGC showcased a strong presence, by sharing updates on our progress toward the consortium's goal of generating chemical modulators for the entire druggable proteome.
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EUbOPEN retweeted
7 Feb 2023
Register now for @target2035's upcoming webinar on February 21 and learn all you need for @XChem_DLS, a dedicated platform for crystallographic fragment screening. @Darenfearon @DiamondLightSou @KoekemoerLizbe @CmdOxford @EubOPEN bit.ly/3jBYlU6
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EUbOPEN retweeted
3 Nov 2022
🙌 @EUbOPEN is fully committed to #OpenScience and aims to publish all its generated data open and fully #accessible to everyone.
Read our case study 📄 on EUbOPEN to find out our collaboration on making data #FAIR: fairplus-project.eu/news/eub…
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EUbOPEN retweeted
Don't miss your opportunity to take part in the second #CACHEChallenge! The target is the NSP13 helicase of #SARSCoV2. Submit your application to join the CACHE competition. Apply today! bit.ly/3bqngFW
#DrugDiscovery #OpenScience #Target2035
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EUbOPEN retweeted
23 Jun 2022
If you are a postdoc or a PhD student and you want to actively participate in the 2nd Munich-Leiden Virtual @ChemBioTalks, please make sure to check out our abstract challenge. You still have until July 31st to submit your abstract here: chemistry-europe.onlinelibra…
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Happy to share that they liked my flash talk enough to give me a prize at the #SeedpodsDay! Life pro tip, wear a baby bump as a good luck charm!
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This Tuesday JUNE 14 10AM EDT/4PM CEST Target2035 Webinar: Towards Autonomous Bioactive Molecular Discovery! Register NOW target2035.net/upcoming-webi…
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EUbOPEN retweeted
1 Jun 2022
cc: @EUbOPEN
1 Jun 2022
If yes, you might be interested in our new paper in @CellChemBiol authors.elsevier.com/a/1fAB4…, reporting a generalizable TR-FRET assay platform for high-throughput protein quantification - in 96-well plates - in 1 h. @Chemist_Payne in collaboration with @TannousLab.
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EUbOPEN retweeted
18 May 2022
It's here: you can now download all the data on the Chemical Probes Portal! Use our new feature to download the full dataset, choose individual chemical probes or filter by protein target, target family, expert rating etc.
Find out more: chemicalprobes.org/news/new-…
ALT The new download feature for the Chemical Probes Portal. The feature enables filtering by probe name, protein family, Portal rating, mode of action and the date the compound was added to the Portal, as well as the stage in the review process.
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EUbOPEN retweeted
20 May 2022
We're seeking inhibitors of #PLCzeta1 towards new, inexpensive, non-hormonal female contraceptives. You'll work with other target champions across the worldwide @thesgconline - a very strong, collaborative team funded by the Gates Foundation. #globalhealth 2/3
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EUbOPEN retweeted
Groundbreaking work from @CherylArrowsmi1, @thesgconline team @researchuoft, @PMResearch_UHN and research partners released today in @nchembio reveals MS023 induces #antitumor activity for #triplenegativebreastcancer.
Read more here: go.nature.com/3wsL5DH
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Interested in a new challenge? Check out this role for a Senior Scientist and Programme Leader at @CmdOxford cmd.ox.ac.uk/jobs#157818
EUbOPEN retweeted
16 May 2022
This is a great webinar series! @FNucleosome also have YouTube channel youtube.com/channel/UCAnaBy0….
cc: @EUbOPEN
14 May 2022
We are thrilled to announce next week's seminars with @NsBenab & @drkahaynes!!! Get ready for fantastic science on histone modifications & designing reader-effectors!!! Registration is free & open to all! Join us: harvard.zoom.us/webinar/regi… #chromatin #OpenScience #syntheticbiology
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EUbOPEN retweeted
5 Apr 2022
Through its participation in @IHIEurope @EUbOPEN, @Pfizer is helping to support the generation of chemical tools which may help scientists develop compounds that target proteins as specifically as possible. #PFEColleague bit.ly/3ua9TQY
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EUbOPEN retweeted
4 Apr 2022
Our very first @thesgconline Open Chemistry Networks meeting later today (5pm UK). Project 4, SARS-CoV-2 Nsp13 fragment project, chaired by student champ @TomMBK97. Details: github.com/StructuralGenomic… All welcome. #openscience #SGC-OCN #SGCchem @target2035 #FBDD
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EUbOPEN retweeted
6 Apr 2022
The Bullock lab has a new paper in Cell Death Differ “Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation” showing how mutations change E3 ligase substrate recognition. DOI: 10.1038/s41418-022-00983-4
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