ALT Cover image: Pictured is a regenerating root from an Arabidopsis thaliana leaf. Akansha Ganguly et al. detached plant leaves to study the mechanisms of stress mitigation associated with wound repair. The authors found that plant-specific PLETHORA transcription factors activate the ATG8 gene, which initiates recycling of damaged cell components to decrease intracellular stress and allow stem cells to differentiate. ATG8 is not activated if the plant is simply forming a callus, rather than regenerating roots. The results reveal how plant-specific autophagy regulators interact with intracellular stress signaling to aid in wound repair. See the article by Ganguly et al., e2513954123. Image credit: Akansha Ganguly.