ALT Figure showing three possible mechanisms to remove interlocks and the accompanying chromosome movements required for expulsion of the entrapped chromosome(s). The initial interlock is indicated by a black arrowhead. The direction of chromosome movements is indicated by the gray arrows. The SC is shown in yellow. Rearrangement of telomere position following SC disassembly is shown by teal and pink arrows. Telomere attachment to the NE is indicated by gray blocks. The only model that requires detachment of one or both telomeres is the ‘pull-through’ model. Although both Brownian and motor-driven chromosome motions are random in their direction, we highlighted the specific motions that would result in a change to chromosome configuration.