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Brian Theyel @TheyelLab
Joined January 2024
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An image submitted alongside our recent publication in eNeuro was chosen to be featured as a coverslide on eNeuro's homepage for the next week. Check it out at eNeuro.org! (look for a rainbow of action potentials)
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Brian Theyel retweeted
Brown Psychiatry and Human Behavior@BrownPsychiatry
29 Apr 2024
Neuroscientists and psychiatrists sit at opposite ends of the basic science-to-clinical care spectrum. But Drs. Brian Theyel (@TheyelLab) and Frederic Pouille are collapsing that gap with a rare research collaboration thanks to @CarneyInstitute. More: go.brown.edu/TheyelPouille
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Check out our recent papers! They show that two important types of neurons implicated in epilepsy, schizophrenia, autism, and other disorders, can fire 'on their own' during periods of hyperexcitability. pubmed.ncbi.nlm.nih.gov/3863… pubmed.ncbi.nlm.nih.gov/3803…

Activity-Dependent Ectopic Spiking in Parvalbumin-Expressing Interneurons of the Neocortex - PubMed

Canonically, action potentials of most mammalian neurons initiate at the axon initial segment (AIS) and propagate bidirectionally: orthodromically along the distal axon and retrogradely into the soma...

pubmed.ncbi.nlm.nih.gov
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...and here's the link to the second one: pubmed.ncbi.nlm.nih.gov/3803…

Activity-dependent ectopic action potentials in regular-spiking neurons of the neocortex - PubMed

Our findings suggest that pyramidal cells can integrate information over long time-scales before briefly entering a mode of self-generated firing that originates in distal axons. The surprising...

pubmed.ncbi.nlm.nih.gov
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