Graduate Student in the Raivio lab studying how bacteria sense and respond to stresses @UAlberta

Joined June 2019
5 Photos and videos
Pinned Tweet
11 Apr 2024
Super happy to see this out! Thank you to all current and previous @traivio and Glover lab people for making this project possible. An especially big shoutout to my talented co-author Cameron Murray for providing indispensable expertise and insight. 🔬🦠 jbc.org/article/S0021-9258%2…
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Tim Cho retweeted
Why do Pseudomonas aeruginosa have not one, but two MlaA-like proteins? Turns out that one protein is part of a classic maintenance of lipid asymmetry pathway while the other joins forces with a periplasmic phospholipase!   pnas.org/doi/10.1073/pnas.23…
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Tim Cho retweeted
New! Gram- cells need lipoproteins to build their surface. LolA & LolB deliver these in E.coli. But many species only have LolA - where's LolB? For Caulobacter, LolB is... LolA! It's a bifunctional protein! We can even tweak E.coli LolA to do double duty! pnas.org/doi/10.1073/pnas.22…
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17 Jan 2023
the first plate i pour vs the last plate i pour
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Tim Cho retweeted
#PeerReview from @eLife of 👉🏿 A frameshift in Yersinia pestis rcsD leads to expression of a small HPt variant that alters canonical Rcs signalling to preserve flea-mammal plague transmission cycles biorxiv.org/content/10.1101/… #biorxiv_micrbio #reviewedpreprint

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Tim Cho retweeted
I’m excited to share our historical perspective on the outer membrane of Gram-negative bacteria! Here, we dive into the experiments that have built our understanding of outer membrane structure, function, and biogenesis. sciencedirect.com/science/ar…

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29 Nov 2022
A review I co-wrote on ESRs with my talented labmate @kpick97 (and the one and only @traivio) is finally out! It's a chonker but we hope it becomes a useful resource for people to learn about these key bacterial systems! authors.elsevier.com/c/1g9xg…

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Tim Cho retweeted
Today, we’re introducing a new model that eliminates accept/reject decisions. By publishing every paper with eLife reviews as a Reviewed Preprint, we plan to restore autonomy to authors, ensuring that they will be judged by what, not where, they publish. elifesciences.org/inside-eli…
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20 Oct 2022
Our preprint on how lipoprotein-OMP complexes mediate signaling from the outer membrane was just uploaded to bioRxiv! Give it a read if you got some time.
NlpE is an OmpA-associated outer membrane sensor of the Cpx envelope stress response biorxiv.org/cgi/content/shor… #biorxiv_micrbio
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20 Oct 2022
Tim Cho retweeted
Over at @eLife, we’re eliminating accept/reject decisions and relinquishing the traditional journal role of gatekeeper. This new model is our move towards a fairer system that helps researchers get recognition for what, not where they publish. Read more: elifesciences.org/articles/8…
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Tim Cho retweeted
NlpE is an OmpA-associated outer membrane sensor of the Cpx envelope stress response biorxiv.org/cgi/content/shor… #biorxiv_micrbio

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Tim Cho retweeted
Busy on the Caulobacter project with @LaskerKeren -- I worked up the cell wall this morning. First time doing an S-layer! Wow! It's still missing the soluble periplasmic proteins and all the inner membrane proteins at the condensate.
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Tim Cho retweeted
DNA Enzymes explained with earphones 🧬🎧
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24 Aug 2022
idk how they found footage of me whenever costco restocks john wm macy's cheese crisps
12 Aug 2022
new yeezys just dropped 🔥🔥🔥
Cellulose shoes made by bacteria | Nature Biotechnology short profile of our collaborators and friends at Modern Synthesis nature.com/articles/s41587-0…
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a photo of me doing simple dilutions without a calculator
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Tim Cho retweeted
Simulated colonic fluid replicates the in vivo growth capabilities of Citrobacter rodentium cpxRA mutants and uncovers additive ... biorxiv.org/cgi/content/shor… #biorxiv_micrbio

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Tim Cho retweeted
Scissors? You mean Parafilmase?
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