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Traffic Journal @TrafficJournal

@wileynews "Traffic: The Moving Front of Cell Biology." Journal covering the cell biology and biochemistry of intracellular transport in health and disease.

Joined November 2018
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🎉 Celebrating 50 years since the discovery of #Clathrin! The first article in Traffic’s Special Issue is now online, with many more contributions from leaders in membrane trafficking and cell biology to come. Edited by Emanuele Cocucci onlinelibrary.wiley.com/doi/…

Clathrin‐Mediated Endocytosis in Plants: Historical to Modern Advances

Ultrastructural studies by Bonnett and Newcomb in 1966 revealed the existence of coated vesicles budding from the plant cell plasma membrane. This review introduces this discovery and early questio...

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The Lack of a COPII Cargo Receptor Erv14 Impacts Physiological Functions of the Vacuole in Saccha...

Loss of the cargo receptor Erv14 in Saccharomyces cerevisiae results in sensitivity to calcium, zinc, neutral extracellular pH, and elevated temperature. Furthermore, cells deleted in the ERV14...

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A Toolbox for Quantifying Nuclear and Nucleolar Protein Accumulation Using NLS and NoLS Fusion...

Fluorescent proteins fused with nuclear (NLS) or nucleolar (NoLS) localization signals are commonly used for live assessment of protein accumulation in the nucleus and nucleolus. We present a...

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Unraveling the Dynamics of Oxytocin in Hypothalamic Neurons

Oxytocin (OT) plays an important role in regulating social behavior, and dysregulation of the oxytocinergic system leads to social impairments, such as autism spectrum disorder. Central OT release...

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Traffic Journal retweeted
Neil Stone
@DrNeilStone
Mar 29
Complete crap here from your HHS Secretary The HPV vaccine (Gardasil) is so effective it is on the way to ELIMINATING cervical cancer! RFK Jr is an anti vaccine fanatic who would rather your daughter got cervical cancer than a vaccine Horrible

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KIF5B and Dynein‐Dependent Golgi Organization: Role in Adhesion‐Dependent Microtubule Acetylation

KIF5B and dynein regulate Golgi organization and localization- Role in regulating MT acetylation: In control (CNT) cells, active Arf1 facilitates the recruitment of KIF5B and dynein to the Golgi,...

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Protein Kinase D Regulates Kinesin‐Mediated VEGFR2 Trafficking and Influences Retinal Endothelial...

Upon VEGF binding, VEGFR2 is autophosphorylated and recruits downstream signaling molecules, leading to protein kinase D (PKD)1 phosphorylation. We found that PKD1 phosphorylates KIF13B, a kinesin-3...

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Palmitoyl Acyltransferases Control the Membrane Localization of DNAJC5 to Regulate Unconventional...

Acylation of DNAJC5 by PAT facilitates its association with the Golgi apparatus, enhancing the secretion of abnormal cytosolic proteins via unconventional protein secretion.

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Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions

Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule-dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential...

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Clathrins Are Involved in the Endocytosis of Host Cytosol in the Malaria Parasite

This study characterized clathrin function in hemoglobin uptake from host red blood cells via the malaria parasite's specific endocytosis machinery, cytostome. Clathrin heavy chain, clathrin light...

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Copper Homeostasis at the Crossroads of Cellular Metabolism, Epigenetic Regulation and Protein...

Copper homeostasis is maintained in the cell by epigenetic regulation, and various metabolic processes. Regulated copper homeostasis balances normal protein trafficking, amino acid metabolism, etc.,...

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The Role of Small Extracellular Vesicles in Tumor Development and the Prospect of Targeted Therapy

Mechanisms of sEV uptake:① Membrane fusion.② Endocytosis.③ Receptor-ligand interaction.

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Beyond the Secretory Pathway: New Insights Into Protein Release

While proteins bearing N-terminal signal or leader sequences are secreted via the ER-Golgi-plasma membrane axis of the conventional secretion pathway, many cytosolic proteins lacking signaling...

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Virion Associated Importin Subunit Beta‐1 Augments Nuclear Import of HIV‐1 Pre‐Integration Complex

Viruses produced from CD4 T lymphocytes exhibit significantly higher infectivity than HIV-1 viruses egressing from virus-restrictive cells like astrocytes. Importin β1, a key karyophilic protein,...

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Spatiotemporal Analysis of Glucagon Secretory Granule Dynamics

The schematic abstract illustrates the workflow of the study. Confocal image stacks were acquired from α cells (glucagon granules) and β cells (insulin granules) labeled with ZIGIR. Single-particle...

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Strain‐Dependent Immune Signaling by Small Extracellular Vesicles Derived From Trypanosoma cruzi‐...

Chagas disease, caused by Trypanosoma cruzi, remains a major treatment challenge due to variations in host immunity and parasite strains. We found that small extracellular vesicles (EVs) from...

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From Mechanisms to Therapy: Exploring the Role of Ferroptosis in Cervical Cancer Transformation and...

This review mainly discusses the role of ferroptosis in cervical cancer from four aspects: underlying mechanisms, stage-specific sensitivity, ferroptosis-related targets and biomarkers, and clinical...

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Traffic Journal retweeted
Traffic Journal@TrafficJournal
3 Sep 2025
Editor's selected articles of the last two years onlinelibrary.wiley.com/doi/…

Editors Choice Articles: Traffic

Traffic is a cell biology and biochemistry journal devoted to intracellular transport, covering subcellular trafficking, membrane dynamics, organelle function & more.

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Traffic Journal@TrafficJournal
16 Jul 2025
See the latest publications onlinelibrary.wiley.com/jour…. Traffic is also on BlueSky bsky.app/profile/traffic-jou…

Traffic

Traffic is a cell biology and biochemistry journal devoted to intracellular transport, covering subcellular trafficking, membrane dynamics, organelle function & more.

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