Research fellow at the Department of Chemical Sciences of the University of Naples Federico II
Joined November 2011
- Tweets 30
- Following 718
- Followers 72
- Likes 431
1 Photos and videos
Romualdo Troisi retweeted
Apr 15
#ChemBioChem @TroRom and coworkers (at @DscUnina @UninaIT @HelmholtzMunich @CNRsocial_) uncover how the catalytic domain of human CDC25B binds 3-O-methylfluorescein phosphate #OpenAccess doi.org/10.1002/cbic.2026000…
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Mar 30
Structural studies on CDC25B phosphatase in complex with 3-OMFP reveal how the ligand binds within the active site, engaging key regions and inducing conformational changes that stabilize the protein.
@UninaIT @CNRsocial_ @HelmholtzMunich
dx.doi.org/10.1002/cbic.2026…
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4 Feb 2025
The X-ray structure of the adduct formed upon reaction of aurothiomalate with apo-transferrin: gold binding sites and a unique transferrin structure along the apo/holo transition pathway
@InorgChemFront #MNESYS #PNRR @esrfsynchrotron
@DscUnina
pubs.rsc.org/en/Content/Arti…
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27 Jan 2025
Investigating the structural effects of anti-thrombin anticoagulant aptamers on activation of human prothrombin
biorxiv.org/content/10.1101/… #Preprint @biorxivpreprint #Coagulation #Anticoagulant #Aptamer #BiophysicalAnalysis
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29 Dec 2024
The structure of the cisplatin adduct of the apo human serum transferrin (hTF) was solved and compared with that formed by the drug when hTF binds Fe(III) at the C-lobe only.
@InorgChem @ACSPublications #MNESYS #PNRR @esrfsynchrotron @DscUnina
pubs.acs.org/doi/10.1021/acs…
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Romualdo Troisi retweeted
20 Sep 2024
🏅PREMIO PRIMO LEVI 2023: i finalisti!🏅
Ultimo ma non per importanza, chiudiamo la rassegna con @TroRom da @UninaIT con il suo articolo candidato al #PremioLevi2023
Video: youtu.be/dnhD3lJmiZ4
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Romualdo Troisi retweeted
13 Jun 2024
🔬 New Insights into G-Quadruplexes and Protein Interactions
G4s can bind selectively to target proteins, and their structural versatility suggests new approaches for medical treatments.
Illustrations made using #protienimager
The paper doi.org/10.1016/j.sbi.2024.1…
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11 Jun 2024
Our latest review "Structural overview of DNA and RNA G-quadruplexes in their interaction with proteins" is online on #CurrentOpinionInStructuralBiology SI: Protein Nucleic Acid Interactions (2024)
@DscUnina @CNRsocial_ @COSB_CRSB
doi.org/10.1016/j.sbi.2024.1…
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27 Jan 2024
In our paper now on @DaltonTrans, crystallographic studies reveal that, in the AP-1/DNA systems, the Pt–As bond can break down with time.
@DscUnina @CNRsocial_
pubs.rsc.org/en/content/arti…
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Romualdo Troisi retweeted
25 Dec 2023
Number 5⃣ of the RPTH Top 10 of 2023.
This #RPTHIllustratedreview is a great way to introduce the coagulation cascade to trainees. And it features some of the cutest coagulation factors we've ever seen!
🩸rpthjournal.org/article/S247…
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14 Nov 2023
Our review "Structural Insights into Protein–Aptamer Recognitions Emerged from Experimental and Computational Studies" is now online on @IJMS_MDPI mdpi.com/2560232 #mdpiijms
@DscUnina @CNRsocial_
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Gli studi strutturali sull'aptamero M08s-1 guadagnano la copertina di NAR!
Info:
scienzechimiche.unina.it/avv…
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Romualdo Troisi retweeted
18 Sep 2023
Are you responsible for teaching the #coagulation cascade?
Check out this incredible new #RPTHIllustratedReview for great visuals & the newest insights from experimental and computational studies! bit.ly/3ECoOb7
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Romualdo Troisi retweeted
20 Sep 2023
How an illustrated review should look like! Scientists from the University of Naples just published a review on the structural aspects of the coagulation cascade and it is gorgeousssss! Fantastic illustrations made with #proteinimager, check them out: rpthjournal.org/article/S247…
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13 Sep 2023
After hard but inspiring work, our totally illustrated review has been published in @RPTHjournal
This simple format helps us to deliver the atomic-level knowledge about the blood coagulation to a broad readership.
@CNRsocial_ @DscUnina @proteinimaging
sciencedirect.com/science/ar…
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29 Jul 2023
I am very delighted to share our latest research article published in @NAR_Open
The discussed results have been achieved thanks to the fruitful collaboration among @UninaIT @DscUnina @UTokyo_News_en and @HelmholtzMunich
doi.org/10.1093/nar/gkad634
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5 Jan 2023
The molecular mechanism of how human serum transferrin (hTF) recognizes cisplatin at atomic level is still unclear. Here, you can find the first X-ray structure of the adduct formed upon reaction of hTF with cisplatin: pubs.acs.org/doi/10.1021/acs…
@InorgChem @DscUnina @UninaIT
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29 Nov 2022
A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers
Check it out on #MolecularTherapyNucleicAcids
cell.com/molecular-therapy-f…
@DscUnina @UninaIT @elettrasincro
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19 Apr 2021
Structural and functional analysis of the simultaneous binding of two duplex/quadruplex aptamers to human α-thrombin authors.elsevier.com/c/1cx7S…
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Romualdo Troisi retweeted
30 Jan 2021
New Paper from I04 doi.org/10.1016/j.omtn.2021.… (pdbe.org/6Z8V)
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