Why has immunotherapy been so hard in glioblastoma? A major reason is the immune microenvironment. In this open-access review, we summarize how single-cell genomics is changing our understanding of glioma immune biology — and why we need to think beyond cell types. academic.oup.com/noa/article…

11/ The review is open access, and Figure 1 can be downloaded from the journal site. Please use it in your PowerPoints, journal clubs, lectures, lab meetings, and grant background slides if it is helpful. That was one of the main reasons we made the article open access.

🧬 We’re hiring: Computational Biologist – Cancer Immunology & Rare Cancers We’re building the computational engine behind next-generation immunotherapies. Our lab at Case Western Reserve University is seeking a computational biologist to work at the intersection of: • Single-cell genomics • Spatial transcriptomics • Tumor immunology • Brain tumors & rare cancers This is a central, high-impact role — working directly with patient-derived datasets to define immune programs that inform therapy. Ideal background: strong bioinformatics training, R/Python fluency, single-cell experience (spatial/multimodal a plus). Two scientists currently in this role are now headed to MSTP/PhD training at CWRU this summer. Apply: lnkd.in/gNpXUVtT Lab: tymillerlab.org/ #computationalbiology #singlecell #spatialbiology #rarecancer