ALT Words: 2025 Reflections & a Bold Vision for 2026BI Logo and three pictures. Picture one: three people speaking on stage Picture 2: Poster competition in process Picture 3: BI lab tour

ALT ALT Text: Photo - Dr. Cindy Chestek Words - Michigan Research - December 2025: From Discovery to Real-World Impact

ALT ALT Text: Photo - Dr. Sunitha Nagrath Words - A Blood Test That Shows If Brain Cancer Treatment Is Working, “There are tiny particles floating in patient blood, called extracellular vesicles, that have been released by the cancer cells. The big challenge is figuring out how to find and pull out only those that come from cancer cells and not from elsewhere in the body,” - Dr. Sunitha Nagrath

ALT ALT Text: Photo - Dr. Sunitha Nagrath Words - Dr. Sunitha Nagrath Appointed Dwight F. Benton Professor of Chemical Engineering

ALT ALT Text: Photos - Dr. James Moon, Dr. Steven Schwendeman, Dr. Anna Schwendeman, Dr. Guizhi (Julian) Zhu, Dr. Peter Tessier

ALT ALT Text: Photo - Dr. Anna Schwendeman Words - Researchers Shine New Light on the Complex Nature of Rituximab, A new study just revealed not all batches of Rituximab (Rituxan®) are created equal. These findings highlight how critical rigorous quality control and careful characterization are for biologic medicines

ALT ALT Text: Photos - 991 Call, Security, Women on Ice, Scientists in Lab, Calling Co-worker, Getting out of the car Words - Season Days Safety Reminder, During the colder season, it is extremely important for us to practice our safety skills to avoid injury and accidents!, Call 911 for any life threatening events, Campus Security Reach out for assistance: (734) 763-1131, Be cautious when walking be wary of slipping due to weather conditions, Working Buddy: Working during non-business hours, weekends, and/or holidays? Coordinate a buddy to accompany you in case of an emergency, Phone a Co-Worker: Arrange to phone a co-worker when you arrive and exit in case of emergency, Avoid Balancing on One Foot When Exiting/Entering Car: Place both feet on ground, as well as using car door/cab handle to steady yourself

ALT ALT Text: Photo - Dr. Deepak Nagrath Words - Digital-Twin Models Bring Patient-Level Metabolic Flux Analysis to Brain Cancer, A new study by the Deepak Nagrath lab unveils two machine-learning, powered frameworks that estimate metabolic fluxes directly in brain-cancer patients, a major advance over prior studies limited to preclinical models.

ALT ALT Text: Photo - Dr. Joerg Lahann Words - Joerg Lahann Helps Secure Third NIH Grant, This achievement underscores Lahann’s commitment to translating bold bioengineering into real-world impact setting a new bar for non-invasive treatment of early-stage tooth decay

ALT ALT Text: Photo - Dr. Lonnie Shea Words - U-M Awards New Commercialization Fellowships: Including Shea Lab Innovator, Among the awardees is Brian Ross (PI: Lonnie Shea lab), whose work on advanced cell-capture scaffolding is advancing toward real-world impact under the startup Porosity Bio.

ALT ALT Text: Photo - Dr. Colin Greineder Words - Skeletalis Raises $8M for Osteoporosis Treatment, With regulatory momentum (e.g., FDA’s recognition of bone mineral density as a valid endpoint), Skeletalis is well-positioned to reshape chronic bone care.

ALT ALT Text: Photo - Kotov Lab Celebrating Words - Kotov Lab Wins Best Department Spirit Award at the ChE 5K Fun Run!

ALT ALT Text: Photo - Dr. Sunitha Nagrath Words - New Insights Into Early Dissemination in DCIS, This study reveals a surprising insight: even in non-invasive DCIS, tumor cells can already be on the move. Using innovative technology from Dr. Sunitha Nagrath’s lab, the team detected circulating tumor cells that could help predict risk earlier and pave the way for more personalized breast cancer care.

ALT ALT Text: Photo - Dr. Peter Tessier Words - Hijacking the Brain’s Highways for Better Therapies, “We want to inject large molecules — proteins, peptides, nucleic acids — into the bloodstream and have them cross the blood-brain barrier in an efficient and predictable way to get them into the brain interior,” - Dr. Peter Tessier

ALT ALT Text: Photo - Dr. Colin Greineder Words - A New Era for Bone Health Begins, Dr. Greineder’s Latest Venture, With the launch of Skeletalis, the fight to transform bone health enters a powerful new chapter.

ALT ALT Text Photo - Dr. Kody Whinsant Words - Congratulations to Dr. Kody Whinsant on Earning 2025 AlChE NSEF Graduate Poster Award

ALT ALT Text: Photo - Dr. James Moon Words - AI Meets Single-Cell Biology: Next-Gen Biomedical Models, Researchers are exploring how large language models (LLMs) can revolutionize single-cell biology. Their new paper highlights how “single-cell LLMs” could accelerate discovery in genomics, disease modeling, and personalized medicine. The team also calls for open collaboration, standardized datasets, and transparency to make AI-driven biology more reliable and accessible.

ALT ALT Text: Photo - Dr. Joerg Lahann Words - Turning Health Research Inside Out: Collaboration as the Catalyst for Discovery, “The Institute comes at research from the opposite direction—we start by asking “what’s the big problem we want to solve?” And by starting with the big picture, we can identify all the different domains that need to be involved and enable them to work together as a team from the outset,” - Dr. Joerg Lahann

ALT ALT Text: Photos - Dr. Sunitha Nagrath, Dr. Max Wicha Words - Advancement in Noninvasive Blood Test to Guide Breast Cancer Treatment Decisions