Immune regulation, regulatory T cells, inhibitory receptors, LAG3, Nrp1, IL35, cancer immunology, autoimmunity, TCR signaling

Joined March 2017
70 Photos and videos
Excited to share that I have been named the next Chair of the Department of Immunology at Pitt! We have a fantastic department and immunology community here and I’m honored to have the opportunity to help it grow!
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Vignali Lab retweeted
Two new studies present insights into regulatory T cells located in tumors associated with head and neck squamous cell carcinomas and non-small cell #LungCancer. By @Vignali_Lab: scim.ag/46W By @SmithImmunology: scim.ag/46V
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Regulatory T cells are phenotypically and functionally heterogenous in the TME, but what are the transcriptional networks of functionally suppressive Tregs in the TME? Our latest work from the lab and first-author @Feng_Shan_ is out now at @SciImmunology! science.org/doi/10.1126/scii…
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We are indented to members of the @VignaliLab for their help and advice, and colleagues in @UPMCHillmanCC and the Pitt Immunology Department. We are especially grateful to @TakisBenosLab, @BcellBruno, @RobertFerrisMD and all our collaborators for their contributions to this study
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This work is co-published with a complimentary study from @SmithImmunology and @dpardol1 groups, check out their exciting findings in detail at @SciImmunology!
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I'm excited to be co-organizing the next FASEB Autoimmunity meeting with @montserrat!  We have an amazing speaker line up, and these meetings always include fantastic presentations, and outstanding participation and discussion (and are a lot of fun!). Please join us! 1/2
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See this link for more details and registration: web.cvent.com/event/5d8928c4… 2/2

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Tagging @OnkarSayali!
Replying to @Vignali_Lab
Fantastic collaboration with @oesterreichs (co-senior author) and the entire team! Kudos to first author Sayali Onkar! @UPMCHillmanCC @Pitt_PMI
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Amazing collaborative effort and an honor (and fun) to work with @oesterreichs! And kudos to @OnkarSayali
Finally brave enough to enter area of immune-oncology-thanks to @Vignali_Lab🙏 Proud to share @NatureCancer paper on immune landscape in ER #breastcancer with focus on #lobular rdcu.be/c7MWs @UPMCHillmanCC @MageeWomens #lobmob @Adrianvlee @BCRFcure @SusanGKomen #bcsm
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Excited to share our latest paper in @NatImmunol entitled "IFNγ-induction of TH1-like regulatory T cells controls antiviral responses". Kudos to first author @AngelaGocher! @UPMCHillmanCC rdcu.be/c7MWU

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