Neuroscientist, GABAergic synapses, GABA-A receptors, behavior and cognition
Joined February 2017
- Tweets 52
- Following 83
- Followers 218
- Likes 112
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Wei Lu retweeted
27 Mar 2025
Our paper on the critical role of Neuroligin 2 in social behaviors and OCD has been published at @SfNJournals early release. Thanks @WeiLuLab and team for their hard work and support!
A critical role of Neuroligin 2 C-terminus in OCD and social behavior jneurosci.org/content/early/…
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Congrats, Guohao!!! Thank you, @ghwang85 and the team！@dcast421 @AngeloKeramidas @Martin17436419 @wenyan_han @MiriamERM and X-less Shixiao Peng, Qingjun Tian, Lijin Dong and Yan Li!
10.1016/j.cell.2024.09.006
cell.com/cell/fulltext/S0092…
Very happy to share our recent work that shows a new transmembrane protein, TMEM132B, binding to GABA-A receptors and regulating alcohol-related behaviors @WeiLuLab doi.org/10.1016/j.cell.2024.…
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Wei Lu retweeted
1 Oct 2024
Now online! The TMEM132B-GABAA receptor complex controls alcohol actions in the brain dlvr.it/TDtjDF
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Wei Lu retweeted
14 Aug 2024
Researchers discovered that chronic stress disrupts a brain pathway, increasing anxiety, but blocking a key protein in this pathway reversed anxiety symptoms in mice. dlvr.it/TBvDrD
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Wei Lu retweeted
29 Jul 2024
Thrilled to announce our publication in @PNASNews! We've uncovered a key stress-responsive signaling pathway manifesting anxiety and depression, paving the way for novel therapeutics development. Huge thanks to my amazing mentor @WeiLuLab and the team.
pnas.org/doi/10.1073/pnas.24…
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Wei Lu retweeted
28 Nov 2022
So excited that this study is finally out in @NeuroCellPress! @AliciaYChe @amandambuch @Ben_S_Huang @TedSchwartz13
authors.elsevier.com/a/1g9qX…
28 Nov 2022
Gene mutation linked to autism spectrum disorder drives changes in neuronal connection patterns, which could lead to abnormal behaviors, suggests a new preclinical study by a team from @WCM_CNG.
bit.ly/3VgLcgq
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#PLOSBiology: Sleep and wake cycles dynamically modulate hippocampal inhibitory synaptic plasticity dx.plos.org/10.1371/journal.…
In this work we @Martin17436419 @wenyan_han show a wake-specific enhancement of inhibitory synaptic plasticity at PV-synapses onto CA1 pyramidal neurons.
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Thanks Angelo for your critical contributions!
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Wei Lu retweeted
30 Sep 2022
Check out our new biorxiv paper led by @JJSherryWU and @ekfishy targeting the breadth of cortical somatostatin cells and showing their remarkably selective circuitry. biorxiv.org/content/10.1101/…
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My lab @NINDS (research.ninds.nih.gov/gu-la…) is looking for highly motivated postdocs interested in the neural basis of spatial cognition! Please spread the word and recommend good candidates. Thank you! :)
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Congrats! In this study we have generated a knockin mouse line and shown a critical role of S405 of Shisa7, a GABAA receptor auxiliary subunit, in inhibitory transmission and neurodevelopmental behaviors
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Wei Lu retweeted
15 Feb 2022
Thrilled to share our new paper published with @SpringerNature in @molpsychiatry , where we demonstrate the contribution of a specific subunit of GABAARs in syndromic intellectual disability.
rdcu.be/cG34E
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Shisa7-dependent regulation of GABAA receptor single-channel gating kinetics biorxiv.org/content/10.1101/…
Congrats David @dcast421, a tremendous amount of work!
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Great work , Kunwei @Martin17436419 and Ryan @DrRDShep !
4 Aug 2021
New pre-print from @WeiLuLab
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Congrats, Kunwei!
29 Mar 2021
Newest work by @WeiLuLab by @Martin17436419 @wenyan_han! 🎊 🎉
Activity- and sleep-dependent regulation of tonic inhibition by Shisa7 sciencedirect.com/science/ar…
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Excited to share with you our recent review in TINs @TrendsNeuro by @amahan0805 and @DrRDShep!
Regulation of GABAARs by Transmembrane Accessory Proteins cell.com/trends/neuroscience…
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A new signaling mechanism regulating neuroligin2 at GABAergic synapses
28 Jul 2020
New pre-print from the lab in collaboration with @saad_hannan and the Smart lab from @uclnpp : PKA-mediated phosphorylation of Neuroligin-2 regulates its cell surface expression and synaptic stabilisation biorxiv.org/content/10.1101/…
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