Cancer Reports is an international, peer-reviewed, OA journal publishing basic, translational, clinical & interdisciplinary research in all aspects of cancer.

Joined June 2023
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Flemban et al. retrospectively analyzed long-term trends in kidney cancer burden in Saudi Arabia & compared incidence, mortality, years of life lost & disability-adjusted life years by sex for 1982–2023. doi.org/10.1002/cnr2.70603 #CancerReports #Wiley #KidneyCancer #Epidemiology
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Xiong et al. elucidated regulatory axis between METTL14 & VEGFA in hepatocellular carcinoma. METTL14 functions as a critical tumor suppressor by restricting VEGFA-driven angiogenesis via m6A-dependent mRNA destabilization. doi.org/10.1002/cnr2.70592 #CancerReports #Wiley
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Hajivalizadeh et al. reviewed promising pharmacotherapies based on their ability to target core biological mechanisms of cancer-related depression. doi.org/10.1002/cnr2.70587 #CancerReports #Wiley #OpenAccess #Review #Cancer #Pharmacotherapy #Depression @WileyHealth @WileyLifeSci
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Mathibela, Lebelo & Steenkamp assessed effects of cisplatin plus phytocannabinoids on cell proliferation, morphology, cell cycle progression, cell death, & DNA damage, in HeLa, SiHa, & MCF-12A cells. doi.org/10.1002/cnr2.70561 #CancerReports #Wiley #Cisplatin #Phytocannabinoids
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A study by Kawasaki & Kasuyama et al. provides detailed characterization of alterations in estrogen receptor signaling in ER-positive/HER2-negative breast cancers with germline BRCA2pathogenic variants. doi.org/10.1002/cnr2.70558 #CancerReports #Wiley #BreastCancer #Germline #BRCA2
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Tian et al. identified Helicobacter pylori infection-related genes associated with gastric cancer prognosis & developed prognostic risk model that predicts patient outcomes, tumor immune microenvironment & responses to immunotherapy. doi.org/10.1002/cnr2.70511 #CancerReports #Wiley
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Okayama et al. report a case with lung adenocarcinoma cT2aN3M1c stage IVB. Patient developed resistance to dabrafenib & trametinib, but responded to pembrolizumab (ICI). doi.org/10.1002/cnr2.70533 #CancerReports #Wiley #LungAdenocarcinoma #ImmuneCheckpointInhibitor #Chemoresistance
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Takahashi et al. performed retrospective analyses of cancer-specific survival in patients with stage II-III obstructive colorectal cancer. High immune cell infiltration at invasive front associates with favorable prognosis. Full text: doi.org/10.1002/cnr2.70508 #Wiley #CancerReports
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An et al. showed that DNA hypermethylation in promoter region of ZNF382 & low ZNF382 expression correlate with occurrence & progression of diffuse large B-cell lymphoma. doi.org/10.1002/cnr2.70502 #CancerReports #Wiley #DiffuseLargeBCellLymphoma #DNAHypermethylation #ZNF382
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Gadelha et al. analyzed association of WRAP53 & hTERT with clinical outcomes in patients with acute myeloid leukemia (AML). Reduced expression of WRAP53 may serve as biomarker in AML. doi.org/10.1002/cnr2.70464 #CancerReports #Wiley #AcuteMyeloidLeukemia #WRAP53 #Biomarker
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Sun et al. performed single-center investigation of safety & efficacy of hypofractionated radiation therapy in patients with spinal metastases. Reduction in pain scores & re-irradiation rates after hypofractioned radiation therapy. doi.org/10.1002/cnr2.70451 #CancerReports #Wiley
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Jin et al. studied the mechanism by which TMEM59L influences 5-fluorouracil sensitivity via PTPRN-mediated DNA damage response in colorectal cancer. doi.org/10.1002/cnr2.70448 #CancerReports #Wiley #ColorectalCancer #Chemoresistance #DNADamageRespone #TMEM59L #PTPRN
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Song et al. developed universal prognostic model—fatty acid metabolic signature for prognosis (FAMOUS)—as prognostic tool for breast cancer. doi.org/10.1002/cnr2.70427 #CancerReports #Wiley #BreastCancer #FAMOUS #FattyAcid #MetabolicSignature #Prognosis
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Patharia et al. developed a diagnostic method leveraging deep learning techniques to enhance accuracy of lung & colon cancer detection. doi.org/10.1002/cnr2.70439 #CancerReports #Wiley #CancerDiagnosis #Histopathology #DeepLearning
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Mitsui et al. present case study of a patient with metastatic renal cell carcinoma with ocular adnexal metastasis, treated with lenvatinib plus pembrolizumab combinatorial therapy. doi.org/10.1002/cnr2.70437 #CancerReports #Wiley #CaseReport #RenalCellCarcinoma
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Kagawa et al. conducted case study to evaluate clinical efficacy & tolerability of afatinib & osimertinib for patients with EGFR L861R-mutated lung adenocarcinoma. doi.org/10.1002/cnr2.70420 #CancerReports #Wiley #CaseReport #LungAdenocarcinoma
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Yeomans et al. conducted retrospective study to evaluate treatment outcomes in patients with malignant peripheral nerve sheath tumors. doi.org/10.1002/cnr2.70406 #CancerReports #Wiley #OpenAccess #MalignantPeripheralNerveSheathTumors #MPNST #Prognosis #Followup #TreatmentOutcomes
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Pehlivan et al. investigated association between cigarette smoking & poor sleep in patients diagnosed with cancer, using data from National Health & Nutrition Examination Survey. doi.org/10.1002/cnr2.70386 #CancerReports #Wiley #Cancer #Smoking #PoorSleep #SmokingCessation
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Azadi et al. reviewed the roles of nicotinic acetylcholine receptors (nAChRs) in cancer development with their context-dependent activation & downstream effectors. doi.org/10.1002/cnr2.70387 #CancerReports #Wiley #Cancer #NicotinicAcetylcholineReceptor #Therapeutics
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Seto et al. assessed correlation between tumor-infiltrating immune cells, expression levels of TGFβ1 & SMAD3, & survival of patients with small cell lung cancer after treatment with immune checkpoint inhibitors plus chemotherapy. doi.org/10.1002/cnr2.70394 #CancerReports #Wiley
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