Computational Molecular Biology @Technion @biologytechnion
Joined March 2019
- Tweets 122
- Following 67
- Followers 272
- Likes 181
33 Photos and videos
Mandel-Gutfreund Lab retweeted
23 Jan 2025
๐ Viruses vs. Human Cells: The Evolutionary Arms Race๐งฌ
Technion researchers uncover a unique mechanism in human cells that rapidly activates the immune system against viruses. A breakthrough in fighting infections and understanding evolution! ๐ฌ๐งฌ Study in @NatureComms led by Prof. Yael Mandel-Gutfreund & @AArgoetti of @BiologyTechnion
#Biology #Immunology #TechForHealth
technion.ac.il/en/blog/articโฆ
1
8
20
1,441
14 Jan 2025
Weโre thrilled to share our new paper! ๐
This study reveals how the lncRNA NORAD interacts with STAT3 to regulate the antiviral response.
Congratulations to Amir and the entire team for their incredible work!
@BiologyTechnion @TechnionLive
nature.com/articles/s41467-0โฆ
11 Jan 2025
1/7 Iโm excited to share our paper, describing the majority of my PhD, now published in @NatureComms!
We present how the lncRNA NORAD interacts with STAT3 to regulate the antiviral response in human cells. A ๐งต
1
4
14
2,016
Mandel-Gutfreund Lab retweeted
11 Jan 2024
Does anyone know of a gorilla cell line?
And if so, does anyone in Israel have one and is willing to give us a vial?
3
1
6
1,258
Mandel-Gutfreund Lab retweeted
27 Dec 2023
ืื ื ืืืืข, ืคื ืื ืื ืืื ืกืืืฉ, ืืื ืืคืืชื ืืืืื ืืืืื ืืืืจื ืืฆืจืคืชืื ืฉืื @GaliaPolyak ืฉืืฆืืื ืืขืื ืืื ืฉืขืืช ืืช ืืืืกืืจ ืืกืืคืจ ืืืฆืื ืฉืื ืืื ื ืืื ืืื ืื!
ืืื ืืชื ืืืงืจื ืืืื ืืื ืืืื ื12:30, ืืืืื ืืชืื ืืฉืืืข ืขื RNA ืจืืืืืืจื ืืืชืคืชืืืช ืขืืืจืืช (ืืืืขืื ืืืืืืื ๐)
7
2
55
2,312
Mandel-Gutfreund Lab retweeted
30 Aug 2023
Hi RNA feed!
Does anyone here know of a small-molecule or non-protein RNAse inhibitor?
All the RNase inhibitors I found are large proteins that can disrupt my assay
4
1
3
1,334
Mandel-Gutfreund Lab retweeted
2 Jul 2023
๐ฐThe Unexpected Match: STAT3-NORAD Interaction, a Novel Link in Antiviral Defense biorxiv.org/content/10.1101/โฆ
2
2
600
Mandel-Gutfreund Lab retweeted
2 Jul 2023
In summary, a surprise twist in evolution unlocked NORAD's new feature!
It can now mediate the nuclear entry of STAT3, thereby inhibiting the interferon response in primates.
Upon viral infection, NORAD is cleaved, prompting STAT3's exit and activating the antiviral response.
1
2
4
698
Mandel-Gutfreund Lab retweeted
2 Jul 2023
Unfulfilled with its conserved partnership, NORAD found a new match...
Please welcome our preprint on how an ALU element equipped NORAD in the arms race against viruses!๐งต
The Unexpected Match: STAT3-NORAD Interaction, a Novel Link in Antiviral Defense
biorxiv.org/content/10.1101/โฆ
3
8
35
10,297
Mandel-Gutfreund Lab retweeted
10 May 2023
cool!
should be useful
10 May 2023
RBPmap is back!
If you need an accurate prediction of RBP binding sites, look no further >>
rbpmap.technion.ac.il
@BiologyTechnion
@TechnionLive
1
4
568
Mandel-Gutfreund Lab retweeted
10 May 2023
RBPmap is back!
If you need an accurate prediction of RBP binding sites, look no further >>
rbpmap.technion.ac.il
@BiologyTechnion
@TechnionLive
3
8
1,442
12 Feb 2023
RBPmap is currently down due to network issues, we apologize for the inconvenience
1
1
1
334
10 May 2023
We're back online!
x.com/YaelmgLAB/status/16562โฆ
10 May 2023
RBPmap is back!
If you need an accurate prediction of RBP binding sites, look no further >>
rbpmap.technion.ac.il
@BiologyTechnion
@TechnionLive
110
8 May 2023
Amir Argoetti @AArgoetti gave a seminar on his PhD project.
Amir is the first fully-experimental doctorate student graduating from the Mandel-Gutfreund lab, so this was an emotional day.
Incredibly proud of you! We expect great things from you
2
2
24
1,517
8 May 2023
Now, all thatโs left are the thesis and defenseโฆ ๐ค๐คช
1
101
Mandel-Gutfreund Lab retweeted
29 Mar 2023
#lncRNAfeed
Does anyone know how many base pairs around the sgRNA are closed by CRISPRi?
We are debating knockdown approaches of a nuclear lncRNA that is back to back to a protein-coding gene
@YaelmgLAB
1
1
1
1,240
Mandel-Gutfreund Lab retweeted
14 Mar 2023
Iโm honored and flattered to receive The Prof. David and Harriet Gershon Excellence Fellowship.
I would like to thank the Gershon family and committee for choosing me and for appreciating my science and my social activities
14 Mar 2023
Recipient of the Gershon award @AArgoetti gave a short presentation of his project at the Biology Faculty Retreat. Congratulations! We expect great things from you!
@BiologyTechnion
@TechnionLive
5
2
40
1,861
14 Mar 2023
Recipient of the Gershon award @AArgoetti gave a short presentation of his project at the Biology Faculty Retreat. Congratulations! We expect great things from you!
@BiologyTechnion
@TechnionLive
1
12
2,576
14 Mar 2023
Great talk Galia!
We are very proud of you
14 Mar 2023
The very talented @GaliaPolyak represents @YaelmgLAB at the faculty retreat, talking about lncRNAs-mediated regulation of human embryonic development
Great talk Galia! ๐คฉ
@BiologyTechnion
@TechnionLive
1
4
220
1 Mar 2023
Celebrating the beginning of a new semester and welcoming @HibaHassanain and Yuval to the YMG lab with a PASTA night!
Thankfully, Tamar is a pasta master ๐๐ฎ๐น
1
3
11
1,171