Year Zero Ventures Group. We are working to materialize our vision of brighter futures. We aim to enable change at the input layer. @govclab cohort 21.
Joined April 2026
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May 9
An official statement as to what Year Zero means and what we stand for in our work against the delayed future and catalyzing breakthroughs at the input layer of technology:
yearzero.vc/statement
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A huge thanks to @Pioneers21EP for establishing this collaboration with @NSF I-Corps Impact Launch and supporting us through the application process and helping us build our business via @MITVMS !!
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Jun 3
We’re joining @govclab ‘s accelerator! We will leverage fully automated fund formation, agentic AI infrastructure, and systematic capital flow in order to underwrite the tech stack of the next century!
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May 28
The easy software era was already winding down; AI served as the comet strike to end it. Yet the mentality remains. Accelerator programs that began following the 90s boom (ie. @ycombinator) still follow a model that has been deprecated. They pivot to deep tech to stay relevant.
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May 28
The next software era will require the emerging hardware era and its breakthroughs and changes to come to pass.
Every new era comes with a new calendar and chronology, and every new calendar starts with a Year Zero.
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BioAI is failing because biology still lacks a computable state layer. We just published a new essay on a belief that sits at the center of ArcellAI:
We learned how to program computers. We never learned how to program biology.
We have models. We have data. We have tools.
What we still do not have is a system that makes biological and clinical reality explicit, structured, and computable. That missing layer is why AI still breaks across real scientific and clinical workflows.
This piece is about that gap, and about the future unlocked once biology has the equivalent of a true state layer:
- research systems that continuously integrate new data
- clinical systems that adapt to evolving patient state
- biological engineering that becomes increasingly programmable
If we get this right, biological engineering starts to move less like the world of atoms and more like the world of bits. The rate of innovation in biology and medicine begins to resemble software.
That is the direction we’re building toward at ArcellAI.
#AI #TechBio #Biotech #ClinicalResearch #ClinicalAI
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Founder @avelezarce will be in ATX next week for @CapitalFactory 's @healthsupernova. Their premiere healthcare event!
@DrLuisEMartinez and Drew Yashar manage the practice and we're excited to connect.
All - please reach out if you'd like to discuss the furture of AI for science and engineering.
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the operating system powering the next generation of precision medicine linkedin.com/pulse/operating…
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Biomedicine Just Became Executable. ArcellAI Built the Runtime.
We are building the Operating System Powering the Next Generation of Precision Medicine
open.substack.com/pub/alexve…
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