I wrote about the call by frontier labs to start regulating DNA synthesis. I, and many lab biologists, think this would be damaging to American biotech. You can read my thoughts in core memory.

Set is ready @ElonMusk We built it 25min from downtown Austin and can shoot anytime in the next 7 days on 1h notice. Humanity is on the verge of becoming a multi-planet species and spacefaring civilization. My goal with this interview is to help people viscerally feel what that future is going to look like and get everyone excited to help build it.

My second interview with @JimBelosic, Founder of @SendCutSend. 0:15 Beating China in manufacturing requires scale 1:10 Automation is not a magic bullet 2:12 Scaling profitably 4:31 Delivering a great customer experience 8:44 Why SCS raised $110M 11:20 Expectations are promises 15:33 Increasing speed and capacity 18:46 Focusing on customers 22:20 Frugality and generosity 25:06 Creating The Anything Factory 26:33 3pm is the new midnight 27:49 Figuring out the next bottleneck 30:37 Finding buildings with enough power 35:21 Lowering prices 37:36 Gambling to turn on factories faster 39:03 Aim for perfection and you’ll end up at excellence 40:04 Maintaining a maniacal sense of urgency through impatience 41:30 Seeding SCS DNA at new factories 43:08 Solving challenges 45:32 Finding great capital partners 48:40 Focus on customer pain 51:59 Learning from Home Depot 54:16 Bringing manufacturing back to America 55:11 Building capacity creates demand 57:01 Handling demand surges 58:21 Being default skeptical and sensing bullsh*t 1:00:27 Getting back to building

the HighRes MicroSpin is now supported in PLR our second centrifuge after the Agilent VSpin great first PR @claudioreiter! also thanks @_benray and @koeng101!

The era of cyborgs is upon us. In this episode (Substack tomorrow), we hang with Alex Smith who is controlling a robotic hand with his mind. This is the first step toward helping people who have lost limbs, but it's also clear that this technology could push us toward some weird futures. Elective amputations perhaps?

Hey Sri! Nice to meet you here. I have emailed you about 18 years ago when i was working for BGI and i started to assemble genes using oligo pools synthesized with CustomArray. Now i am developing more interesting things using our own oligo microarray synthesizer

“The logical thing to do is to use conventional equipment in an unconventional way to get to scale, and then start modifying the equipment to increase the rate”

I guess this is a good time to announce we are currently in the process of building a set for an interview with Elon. Will be finished next month and should be legendary. Elon - lmk if you're in

We use @pylabrobot to program our laboratory automation in python. What's shocking to me is remembering that many people *don't* do this. Most of the world's laboratory automation uses proprietary software you can't even version control. 🤯 Essay ⬇️

“laid back” is what high agency ppl look like from the outside when they’ve correctly identified which games are worth playing & simply declined the rest.

Automation software is not written in normal languages, and you lose a lot of features because of that! There's really no reason for it either, other than vendors being able to lock you in. So we use @pylabrobot.

HOME. The Artemis II crew has arrived back on Earth, ending a nearly 10-day journey around the Moon. The trip took them farther into space than humans have ever gone before, and now they're safely home with us. go.nasa.gov/41r9eL0

how PLR helps Pioneer Labs automate science: pioneerlabs.substack.com/p/w…

we take less-than-truckload logistics seriously

Artemis II, Dark Side of the Moon

Its insane how good of a filter this is Eliminates 99.9% of people

some of these are pretty good

Biomanufacturing needs automation to scale. And nothing is more autonomous than biology itself.