🚨NEW PREPRINT🚨We sequenced the genomes of 334 mosquitoes in Tanzania to investigate the population genomic structure of Anopheles funestus, a dominant malaria vector in eastern and southern Africa.
biorxiv.org/content/10.1101/…
New research on Anopheles funestus in Africa reveals high genetic diversity, widespread insecticide resistance, and promising targets for gene drive vector control. 🦟
Read the full pre-print on the genomic diversity of this important malaria vector
biorxiv.org/content/10.1101/…
Develop your talent for research. Our fully-funded, 4-year MRC Doctoral Training Partnership (DTP) is now open to applicants for an October 2025 start.
Apply by 23:59 on 4 December 2024.
Find out more: lstm.ac/MRC-DTP
The cryptotype paper is out!
A genomic epidemiology puzzle: how do parasites separated by thousands of km share more than 20 co-inherited loci across the genome? What is the function of this complex genetic background?
Read about it on The Lancet Microbe! thelancet.com/journals/lanmi…
Curious to learn more about the work that went behind making BELKA accessible through Polaris? Learn more about Dataset v2.0 and how we’re helping scientists focus on research, not on data wrangling. 👇🧵
Read the blog: polarishub.io/blog/dataset-v…
Access BELKA: polarishub.io/datasets/leash…
📢 Exciting news! 📢
Applications are now open for the 4th iteration of the @pamcaafrica-MalariaGEN virtual training course in data analysis for genomic surveillance of African malaria vectors 🦟
More info about modules, key dates, and how to apply: malariagen.net/article/call-…
ALT Free online training course: data analysis for genomic surveillance of African malaria vectors 2025
Offered in both English and French!
Course dates: 2 April to 11 June 2025
Application deadline: 1 January 2025
ALT The course will run for 11 weeks with whole-day workshops on Wednesdays
What a difference an algorithm makes! I added an implementation of Philip Clausen's dynamic neighbour-joining to anjl, so simple yet crazy fast. Short blog post on NJ algorithms, plus a couple of small things I learned about accelerating Python code with @numba_jit ...
alimanfoo.github.io/2024/10/…
Growing capacity for genomic data analysis in Africa = improved #malaria vector control 🖥️
Today, participants from the 3rd cohort of the @pamcafrica-MalariaGEN training course in data analysis for the genomic surveillance of African malaria vectors met for a virtual hackathon👏
ALT 2024 virtual hackathon for participants of the 3rd training course in data analysis for the genomic surveillance of African malaria vectors
🚀 We are thrilled to announce the release of the Icechunk storage engine, a new open-source library and specification for the storage of multidimensional array (a.k.a. tensor) data in cloud object storage.
Read our blog post about Icechunk here: earthmover.io/blog/icechunk
If you're actively working with data from the vector observatory, please see this update about a new cohorts analysis version:
malariagen.github.io/vobs-up…
I've made a small Python package which provides fast implementations of neighbour-joining. Includes an implementation based on the rapid algorithm which scales pretty well and should work on ~10,000 samples or more. Also interactive plotting with plotly.
alimanfoo.github.io/anjl/
How do you use MalariaGEN data resources?
We're collating information on how MalariaGEN resources are being used to build an evidence base for their importance. This will help secure further funding for their maintenance and growth.
Fill out the survey📝
docs.google.com/forms/d/e/1F…
ALT MalariaGEN data resources evidence base survey
Today, participants from the 3rd cohort of the @pamcafrica-MalariaGEN training course in data analysis for genomic surveillance of African malaria vectors presented their research at a mini-symposium.
It’s exciting to see #malaria genomics capacity continue to grow in Africa! 🧬
ALT Screenshot of the virtual mini-symposium where participants from the third cohort of the PAMCA-MalariaGEN training course in data analysis for the genomic surveillance of African malaria vectors showcased their research.
Jacob Tennessen of @HarvardChanSPH discusses insights from the Ad1000G project, which has sequenced over 1000 samples of A. darlingi mosquitoes, the primary malaria vector in South America. Preliminary analysis notes potential signs of insecticide resistance 🦟
#GEM2024
ALT Ad1000G: A comprehensive, range-wide evolutionary analysis of over 1000 whole genome sequences of Anopheles darlingi, the primary South American malaria vector
New 📄 in @MalariaJournal: Whole-genome sequencing reveals new insecticide resistant variants in malaria mosquitoes in Burkina Faso malariajournal.biomedcentral…
This work was led by Mahamadi Kientega @mkient54, who is presenting a poster on the findings from this study at #GEM2024
ALT Mahamadi Kientega presents a poster on his study on genomic surveillance of the malaria vector Anopheles gambiae populations in Burkina Faso.
Kicking off the first session at #GEM2024 with a deep dive into the Malaria Vector Genome Observatory🦟
Read more about this collaborative effort to sequence the genomes of thousands of Anopheles mosquitoes to improve malaria control: malariagen.net/vobs/
ALT The Malaria Vector Genome Observatory – data, tools and training for genomic surveillance of Anopheles mosquitoes
My commentary on the closure of @VectorBase. Join me in rallying for its sustainable continuation. Comment, repost, and circulate. Let’s ensure this vital resource remains accessible for our global #VectorBiology research community.