AMELIE (Anchored Muscle cELls for IncontinencE) is a ground breaking #H2020 research project using revolutionary #celltherapy to treat #faecalincontinence.

Joined February 2021
118 Photos and videos
It’s World Continence Week, and one of the themes this year is women’s health and incontinence. The AMELIE team is developing a new therapy for people who have faecal incontinence after anal sphincter injury, including injuries caused during childbirth. #continencematters
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Last month we reached the exciting milestone of treating our first patient in the trial. Find out more about how our research aims to improve the quality of life for those affected by faecal incontinence: amelie-project.eu/ #commitmenttocollaborationincontinencecare #WCW2026

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The first patient was recently treated in the AMELIE clinical trial! The team at The Royal London Hospital implanted healthy muscle cells attached to microscopic beads in humans for the first time. Find out more about AMELIE: amelie-project.eu/
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Last week we had the opportunity to present AMELIE (Horizon 2020 funded project) at VC Café London, where we hosted a stand showcasing our approach to treating faecal incontinence and supporting women’s health.
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The discussions also provided useful insights into how health-focused investors evaluate early-stage medical innovations, highlighting the importance of clearly articulating the value proposition, development pathway, and future milestones.
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A very useful learning experience for the team and an encouraging step as we continue developing AMELIE. @QMUL @istecnico @AarhusUni @AUHdk @quironsalud @NHSBT @ucl
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We're showcasing at Venture Café London’s Thursday Gathering, "From Research Gaps to Breakthroughs: Women's Health Innovation", on Thursday 26th February. Register here: community.venturecafelondon.…
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The evening will bring together researchers, entrepreneurs, healthcare evaluators, and investors who are committed to advancing women's health innovation responsibly while meeting the enormous unmet demand for solutions. @QMUL @istecnico @AarhusUni @auhdk @quironsalud @NHSBT
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Patients needed to help with faecal incontinence research! Do you have experience of faecal incontinence? The AMELIE project is developing a new cell therapy treatment, and we need your feedback. @QMUL @istecnico @AarhusUni @auhdk @quironsalud @NHSBT
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If you would like to take part in a short interview, please email info@amelie-project.eu. Find out more about AMELIE: amelie-project.eu #ColorectalSurgery #PelvicFloor #RegenerativeMedicine #ClinicalResearch #FaecalIncontinence

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Clinician input needed! The AMELIE Project is developing a minimally invasive regenerative therapy for faecal incontinence using injectable autologous muscle-derived cells. We’re now seeking insight from HCPs. @QMUL @istecnico @AarhusUni @auhdk @quironsalud @NHSBT
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If you are a clinician involved in faecal incontinence management, could you take part in a 20–40 min confidential interview to help with this study? Email info@amelie-project.eu #ColorectalSurgery #PelvicFloor #RegenerativeMedicine #ClinicalResearch #FaecalIncontinence
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Our YouTube channel now features interviews with the AMELIE research team. Hear from six team members about their roles in this study into improving faecal incontinence after anal sphincter injury. youtube.com/@theAMELIEProjec…
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17 Dec 2025
In case you missed it: This paper looked at whether tiny, implantable beads carrying human muscle cells can be safely frozen and stored for later medical use. amelie-project.eu/publicatio…

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17 Dec 2025
The researchers tested different freezing and thawing methods and found that the muscle cells survived well, stayed attached to the beads, and still behaved normally after thawing. The beads themselves also remained structurally sound.
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17 Dec 2025
This means that in the future, these cell-based treatments could be produced in advance, stored in a “cold chain” and delivered to hospitals when needed, making regenerative therapies much more practical and accessible.
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17 Dec 2025
The AMELIE project has taken great strides this year! We saw the compilation of documents for regulatory approval, and received UK and EU clinical trial authorisation. And we recently recruited the first patient! Find out more: amelie-project.eu
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