Here’s my anecdote. 100% of patients who came to me after having persistent unexplained bleeding on pellet HRT had type 1 endometrial cancer.
None were informed of the risk because they were on a progesterone. None were offered an ultrasound. None were offered a biopsy.
So venturing out into a world of TRT, HRT, anabolics, and peptides where we have no “rules” more than first principles, known mechanism, and anecdotes, often informed by bioscience, to put together working protocols? Nbd.
Not everyone can work like this.