We empower visionary, high-leverage science and technology projects with the capacity to create transformative progress for human civilization.
Joined December 2020
- Tweets 260
- Following 29
- Followers 9,968
- Likes 230
32 Photos and videos
Astera Institute retweeted
Jun 11
How do we simulate Mars here on Earth?
We scrutinized Mars rover data so you don’t have to. 😛
Here’s what it tells us about how to simulate Mars on Earth, and which organisms could grow on Mars!
📄 Report: biorxiv.org/content/10.64898…
1
4
10
6,159
To realize AI for science, we have to change how we feed the machine. sampleworks, the first publication from @radialscience‘s @diffuseproject is a step: an open, modular platform for building and benchmarking structure predictors against experimental data 👇
1
2
8
1,489
First results show models memorize training structures more than they generalize. Model differences were also revealed, pointing toward new training paradigms for structure-ensemble prediction.
1
1
612
Better models of protein motion mean better tools for understanding disease and designing drugs. And because sampleworks is open from the first commit, anyone can build on it. This is what building science for reuse looks like in practice.
2
254
Astera Institute retweeted
Reimagining Science for the AI Era. Listen to @beckypferdehirt CEO of Radial @AsteraInstitute discuss the $500M nonprofit seeking to create better conditions for AI in biology. Sponsors: @AlphaSenseInc Dash Bio. timmermanreport.com/2026/06/…
2
7
2,974
Astera Institute retweeted
Reimagining Science for the AI Era. Listen to @beckypferdehirt CEO of Radial @AsteraInstitute discuss the $500M nonprofit seeking to create better conditions for AI in biology. Sponsors: @AlphaSenseInc Dash Bio. timmermanreport.com/2026/06/…
3
6
1,817
Astera Institute retweeted
May 27
Congrats @beccajcarlson @BobbyHollings! Another radically open science effort FTW! More thoughts from @beckypferdehirt @AsteraInstitute here asterainstitute.substack.com…
AI has transformed how we design therapeutics.
But targeted delivery is still an expensive guessing game.
Today @BobbyHollings and I are launching @deliverome with @beckypferdehirt and @radialscience at @AsteraInstitute, to fix that. 🧵
1
5
21
4,572
Astera Institute retweeted
May 27
1/ Despite recent advances in the design of next-generation therapeutic modalities, our ability to deliver those molecules safely and precisely to diseased cells remains a bottleneck. The data to find those cellular addresses doesn't exist yet.
Radial at @AsteraInstitute is seeding @deliverome with $5M to build it — openly, at scale, in AI-ready formats.
2
9
34
11,643
Astera Institute retweeted
May 27
I am incredibly excited to support @beccajcarlson and @BobbyHollings in building the @deliverome project.
Read more about why below 👇
May 27
1/ Despite recent advances in the design of next-generation therapeutic modalities, our ability to deliver those molecules safely and precisely to diseased cells remains a bottleneck. The data to find those cellular addresses doesn't exist yet.
Radial at @AsteraInstitute is seeding @deliverome with $5M to build it — openly, at scale, in AI-ready formats.
3
8
48
7,066
May 19
Space science can have surprising impacts here on Earth.
In this essay, @erika_alden_d explores how work on terraforming Mars led to real-world applications — and why pushing scientific boundaries matters.
Read more: open.substack.com/pub/erikaa…
2
2
13
3,684
Astera Institute retweeted
💦 Episode 96: A New Playbook for Deep Tech Fund Investing, Featuring @reallywesp Wes Panek, Head of Fund Investing, Astera Institute, @AsteraInstitute
🎧 Spotify: open.spotify.com/episode/6yi…
🎧 YouTube: youtu.be/LwWC3CxYF48?si=mZGN…
#familyoffice #VC #seeyoulaterallocator
1
2
1,267
Astera Resident @erika_alden_d and @Pioneer__Labs built a whole-genome mutation library and are giving it away. Peer-reviewed, open-access, ready to use. This is how you move science forward.
May 5
This tube is a library of bacteria with every single-base-pair genome mutation, all DNA-barcoded.🧪Growth barcode sequencing = data on millions of mutations.
📄 Report: biorxiv.org/content/10.64898…
Retweet if you want more data, and read on if you want to use the library! 🧵
4
49
5,610
Astera Institute retweeted
Apr 28
Reminder that we are approaching the deadline for our @AsteraInstitute essay competition! What are the bottlenecks you experience in your work as a scientist? What are the greatest uncertainties that prevent progress and could be tested? Deadline May 1! Look forward to hearing some fresh perspectives!
Apr 28
Last call — Astera's Essay Competition deadline is May 1. Scientists see the bottlenecks in their fields better than anyone — we want to hear from you. astera.org/essay-competition
1
10
3,396
Astera Institute retweeted
Apr 28
Please submit if you had ideas! I’m one of the judges!
Apr 28
Last call — Astera's Essay Competition deadline is May 1. Scientists see the bottlenecks in their fields better than anyone — we want to hear from you. astera.org/essay-competition
5
9
5,832
Apr 28
Last call — Astera's Essay Competition deadline is May 1. Scientists see the bottlenecks in their fields better than anyone — we want to hear from you. astera.org/essay-competition
7
30
34,176
Astera Institute retweeted
Just a reminder of @AsteraInstitute's open essay competition about identifying and overcoming scientific bottlenecks. Deadline for entries is May 1!
2
49
155
21,475
Biology’s secret isn’t the material — it’s the manufacturing. Astera Resident @TR_McGee is developing a platform to spin protein fibers using the same principles nature uses at scale. Read more here: asterainstitute.substack.com…
1
3
15
2,127
Inspired? Apply to Astera’s Residency Program: astera.org/residency/
1
1,092
Mar 27
The mission of Astera's AI-Neuro program is easy to state, but daunting to execute— study how the brain works, then use those insights to build AI systems that are more brain-like. Read more in our feature with Forbes: forbes.com/sites/annatong/20…
Join us: astera.org/careers/
1
1
11
2,236