Coffee-fuelled research fellow in Structural Biology at @Bio21Institute @unimelb.
Joined September 2018
- Tweets 26
- Following 208
- Followers 106
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4 Photos and videos
30 Mar 2025
Excited to share that our work on a family of pore-forming proteins is now live in @ScienceAdvances ! We show structural snapshots across the entire pore-forming pathway for a cholesterol-dependent cytolysin-like (CDCL) bicomponent system.
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30 Mar 2025
This work was part of my PhD at UniMelb and was my first foray into cryo-EM! Admittedly, learning the various steps of cryo-EM on proteoliposome samples felt like jumping in the deep end so I am very happy and proud for all to see how it worked out.
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30 Mar 2025
Cryo-EM was conducted at Ian Holmes Imaging Centre at Bio21 Institute with data collected by Hamish G Brown. Done with @Bio21Director, @michchris14, @Riya_Joseph_a, Craig Morton, @big_french_man and Rod Tweten and team.
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24 Dec 2024
Just in time for Christmas, our paper on the structure and evolution of baculoviruses is out! Excited to share some work I did at Monash in the @CoulibalyLab, with shout outs to co-authors @joshuamhardy and Jungmin, collaborators Mart and team and everyone else who contributed!
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24 Dec 2024
Definitely one of the coolest structures I'll ever work on! 🤩
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14 Jun 2024
See our latest work from the Tweten, Comstock and Parker @Bio21Director labs highlighting unique CDC-like bacterial toxins in Bacteroidetes that require proteolytic activation and form two-component pores via a mechanism reminiscent of the complement MAC to target other bacteria
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14 Jun 2024
In addition, we identify an immunity protein much like the mammalian GPI-anchored CD59 that inhibits the MAC pore formation
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14 Jun 2024
This is only the start of our investigation into these novel bacterial toxins and their unique mechanism among pore-forming toxins, so watch this space!
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22 Aug 2023
Very excited to finally be at the start of IuCr2023! Opened today by @Bio21Director and loved hearing the history behind phasing methods that worked successfully for me during my PhD.
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22 Aug 2023
Tomorrow - my turn to share our work on novel pore-forming toxins. Come to session A013 if you are interested in bacterial toxins, pretty structures or both like we are!
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Bronte Johnstone retweeted
16 Jul 2022
Nice review on the current questions around cholesterol dependent cytolysins in @iubmb_life from @bronteaj in the Parker lab @Bio21Institute that the @Mol_Machines group got to be a part of. iubmb.onlinelibrary.wiley.co…
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15 Jul 2021
My first ever conference was MPG as a fresh-faced Honours student, in awe of others. A few years on I feel very fortunate to be selected to present my work, and even more so to win an award, at the 2021 MPG meeting during the final year of my PhD. Thanks for a great meeting!
15 Jul 2021
Congratulations to all the winners of the MPG meeting presentations. Thanks everyone, stay safe and look out for each other #MPG21online
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11 Feb 2021
The pore-forming toxin community has done a fabulous job at achieving crystal structures - although that meant a lot of reading was done in order write this chapter! Happy to see that some of my efforts during working from home in 2020 is now in-press!
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Bronte Johnstone retweeted
21 Apr 2020
Here is a piece I wrote for all you PhD students trying to work during the Pandemic. Spread widely people.
medium.com/@DrShaneRRR/how-t…
#phdlife
#phdchat
#AcademicTwitter
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Bronte Johnstone retweeted
5 Apr 2019
"We need to educate them about the lows and be explicit when describing our needs. PhD students must be noisier when asking for help", says @kate_samardzic go.nature.com/2U7wZXr
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Bronte Johnstone retweeted
31 Dec 2018
Everyday in 2018 I started the @Wikipedia biography of a woman, person of colour or LGBTQ scientist or engineer. I’m up to 450 pages so far 😁 #womeninSTEM x #HappyNewYear
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Bronte Johnstone retweeted
10 Dec 2018
Its official! Come and meet the newest constellation of #SuperstarsofSTEM - these 60 women will forge new stereotypes and show girls and young women that they can be what they can see. #womeninSTEM buff.ly/2LR5oFI
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