Applied mathematics, biology, computational neuroscience

Joined December 2010
65 Photos and videos
At Pitt in the late 90's, we used this great database tool from Peoplesoft. Oracle knew it was better and did a hostile takeover, which no one thought would succeed and we were stuck with their inferior product. I knew Paramount would win Warner because Larry never quits.
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26 Nov 2025
Has anyone told Elon that there is such a thing as reversible computing (which means there is no minimum amount of energy needed), so you can have super AGI and not need all the power in the galaxy to run it?
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18 Oct 2025
If Karpathy is correct, and he usually is, then current AI is just the perfect homework doing machine. I would hate to be a student today.
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18 Oct 2025
We need AGK, artifical general kindness
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18 Oct 2025
The world right now does not lack IQ, it lacks compassion and wisdom
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18 Oct 2025
It's not like people are saying AGI will suddenly make SHA-512 encryption obsolete. All these Bitcoin farms won't go away with AGI so why does everyone think biology is easier?
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18 Oct 2025
That is biology. It is not IQ limited. AGI won't suddenly find the guests. You have to try the keys in the locks. There is nothing specific about GLP-1 that makes it magical. The body could have chosen any number of hormones. We are the end result of a bunch random events.
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18 Oct 2025
Imagine a giant hotel with a trillion rooms and each room has a thousand locks. You need to find 100 guests in 100 different rooms. Now you are given 20000 keys and you have to figure out what combination of keys opens the locks. That is all you know. How do you find the guests?
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10 Oct 2025
Where can I get some cheap used A100s?
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3 Oct 2025
Anyone have a spare A100 I can use during the shutdown?
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3 Oct 2025
I kind of don't get it. Anthropic, Google, OpenAI, etc. are telling me that they will cure cancer and all diseases in 2 years, yet their former employees keep starting new companies to do the same. What am I missing?
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1 Oct 2025
Anyone looking to hire an over the hill math biologist with a PhD in plasma physics?
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30 Sep 2025
I plan to work through the shut down. Just letting you know now in case I'm put in jail for working.
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12 Sep 2025
Saying that universities need to teach students how to use AI is like saying you need to teach people how to use chauffeurs. No, we should take all devices away from students and make them actually read and write.
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11 Sep 2025
Coding by hand is like gradient descent to an optimum. Vibe coding is markov chain monte carlo.
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20 Jun 2025
Suppose someone believes AI agents don’t work as well as hypothesized in the near future. Is there a way to arbitrage this?
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11 Jun 2025
Am I the only one who thinks there is probably an impossibility theorem that says you can have either truly autonomous AGI or alignment but not both?
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