Joined July 2016
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Death on the Beach: Cell Death & Disease 32nd ECDO Conference 📍Favignana, Italy 🗓️ 16-19 September 2026 📌 Abstract submission deadline: 30 June 2026 More info: ecdo2026.com/ Preliminary programme: ecdo2026.com/ecdo2026-progra… @ECDOorg #CellDeath #Conference
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“The promyelocytic leukemia PML protein coordinates immune evasion in triple-negative breast cancer via independent and converging mechanisms” A new study from @BernardiLab uncovers a potential new target to boost immunotherapy ⤵️ nature.com/articles/s41418-0…
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“Single cells and spatial RNA profiling reveal that inflammatory fibroblasts arise from Edil3 stromal cells in the colon after irradiation” This study offers key insights into the colonic stroma composition ⤵️ nature.com/articles/s41418-0…
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“A PML1-CCL5-PI3K/MAPK feedback loop governs survival of endocrine-resistant breast cancer cells” This study by @HanWang23263640 and colleagues identifies PML1 as a key "resistance hub" ⤵️ nature.com/articles/s41418-0…
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Dive into our June issue here: nature.com/cdd/volumes/33/is…
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“Pancreatic cancer induces B cell lineage plasticity via Pax5 inhibition to sustain immunosuppression” A fascinating immune evasion mechanism whereby PDAC reprograms B cells to acquire a myeloid immunosuppressive phenotype ⤵️ nature.com/articles/s41420-0…
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A new study from @B_Joseph_KI's lab reveals the tumour-supportive role of microglia in DMG and identifies the ECM as a promising therapeutic target ⤵️
Out of the press in Cell Death and Disease the latest findings from our team. #microglia #dmg #dipg #ecm rdcu.be/flx2n
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“Cell death–induced release of the pro-aging protein acyl CoA binding protein (ACBP) into the circulation” ACBP/DBI as a systemic biomarker of cell death and organ injury in humans and mice across multiple disease contexts and experimental models ⤵️ nature.com/articles/s41418-0…
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“When vitamins decide life or death” Explore the multilayered model of vitamin-dependent regulation of cell death in our latest Editorial by Daolin Tang, @melino_G, and Guido Kroemer ⤵️ nature.com/articles/s41418-0…
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“EGFR deletion in myeloid cells reprograms the immunosuppressive landscape of colorectal cancer” A groundbreaking multi-omics study from @CCR_SibiliaLab reveals EGFR in specific myeloid cell subsets as a potential new therapeutic target in mCRC ⤵️ nature.com/articles/s41418-0…
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“Akt-mediated RALY phosphorylation functions as a molecular switch governing c-Myc stability” Researchers uncovered the oncogenic RALY–USP22–c-Myc signalling axis and developed a therapeutic peptide that effectively suppresses tumour growth ⤵️ nature.com/articles/s41418-0…
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1️⃣ day to go. Join us tomorrow!
International Cell Death Seminar 📅 Wednesday 3 June 2026 ⏰ 4:30–6:40pm AEST | 8:30–10:40am CEST 💻 Join us on Zoom: latrobe.zoom.us/j/8244284845… @AusCellDeathSoc @ECDOorg #CellDeath #BiomedicalResearch #Apoptosis #ResearchSeminar
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“NF-κB inducing kinase (NIK) deletion accelerates KRAS-driven pancreatic cancer in association with tumor microenvironment remodeling” Read more about this non-canonical NF-κB pathway in PDAC pathogenesis ⤵️ nature.com/articles/s41419-0…
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“Mitochondrial calcium uptake drives organelle remodeling to promote inflammasome-dependent cytokine release” A mechanistic insight into the intersection between mitochondrial function and innate immune activation ⤵️ nature.com/articles/s41418-0…
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“GSDME acts as an epigenetic modifier to promote melanoma development via centriole biogenesis regulator PLK4” An intriguing oncogenic role for GSDME beyond its canonical pore-forming function in pyroptosis ⤵️ nature.com/articles/s41418-0…
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“Fatty acid channelling into triglycerides and oxylipins drives ferroptosis resistance during oncogenic BRAF-induced senescence” An interesting link between lipid metabolism in OIS cells and their resistance to ferroptosis and oxidative stress ⤵️ nature.com/articles/s41418-0…
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“The E3 ubiquitin ligase Itch plays an essential role in kidney fibrosis by inhibiting Dvl2/GSK3β/β-catenin signaling pathway” A comprehensive investigation into the protective role of the E3 ligase Itch in kidney fibrosis ⤵️ nature.com/articles/s41418-0…
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“LSM7 coordinates scaRNA-mediated snRNA modification to ensure spliceosome fidelity and spermatogonial stem cell differentiation” Mechanistic insights into post-transcriptional control of male germ cell development ⤵️ nature.com/articles/s41418-0…
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“Transcription-coupled nucleotide excision repair protects against genomic instability and cell death induced by the liver toxin methyleugenol” Read how TC-NER, rather than GG-NER, is crucial for resolving ME-induced DNA lesions ⤵️ nature.com/articles/s41419-0…
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“Bon appétit, your phagocyte” New perspective in CDDiscovery on how apoptotic cells undergo a meticulous ‘meal preparation’ process to be optimally suited for consumption by professional and non-professional phagocytes ⤵️ nature.com/articles/s41420-0…
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