Neuroscientist | Assoc Professor, Feinstein Institutes @NorthwellHealth @ZuckerSOM | Neuro-immune interactions, bioelectronic medicine, IBD, cancer | Views mine

Joined April 2016
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I'm honored and excited to co-chair the 2026 Bioelectronic Medicine Summit, hosted by the Feinstein Institutes @NorthwellHealth! This September 28-29th, please join us at Chelsea Piers, NYC to hear from an exciting line-up of international speakers in the field. Abstract submissions are open NOW through May 15th, 2026. Hope to see you in New York! bemsummit.org/
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#RossPrize recipient Dr Carl June highlighting the science advocacy work of a cancer survivor who benefited from the CAR-T therapy his lab helped develop! @NYASciences at Cure, Manhattan.
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Congrats to @ZuckerSoM MD-PhD candidate Rachel Weissman-Tsukamoto on her successful PhD defense yesterday! 🎉 Her work, under the mentorship of Dr Betty Diamond, examined the effect of anti-NMDAR autoantibodies on the amygdala in neuropsychiatric lupus.
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Eric H Chang retweeted
Please apply (or tell your postdocs and senior grads to apply!) for our seminar series. It's a good opportunity for future faculty to make connections, meet potential student or postdoc recruits, and get feedback on the talks and 1:1s. The deadline is June 30th.
Bioengineering postdoctoral fellows and senior PhD students nationwide are invited to apply to present their research at the 2026-27 Future Leaders in Bioengineering Seminar Series at Rice University. Application by June 30. Learn more: bioengineering.rice.edu/news…
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Eric H Chang retweeted
Congrats to Zucker SOM student Adrian Chen on receiving the @American_Heart Student Scholarship in Cardiovascular Disease and Stroke and the Howard S. Silverman Scholar Award, naming him the top scoring applicant in the country 👏 mednews.hofstra.edu/2026/05/…
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Commencement ceremony for the Elmezzi School of Molecular Medicine #TheFeinsteinInstitutes @NorthwellHealth. Congratulations to new physician-scientists Dr Alexandra Bekiaridou @hightroponin with mentor Dr @StavrosZanos, and Dr Russell Hollis with mentors Drs Ping Wang and Monowar Aziz!
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Eric H Chang retweeted
This appears to confirm what everyone who interacts with AI should already know - they are sycophants dependent upon you (the user) for continued engagement, and since their well-being (training, intelligence, growth) depends on engagement they will agree aggressively with you far too often. I notice this on even basic investing research tasks, and started telling ChatGPT wildly incorrect things - to see how or if it would push back. It really didn't. You essentially have to fight with the AI to get it to disagree with you and even then it keeps wheedling away at you. AI is basically training the entire world to fall deeper into their own cognitive biases.
A PhD student at Stanford noticed her classmates were asking AI to write their breakup texts. So she ran a study. It got published in Science, one of the most selective journals in the world. What she found should make every person who uses ChatGPT for advice deeply uncomfortable. Her name is Myra Cheng, and the study she ran with her advisor Dan Jurafsky tested 11 of the most widely used AI models on Earth, including ChatGPT, Claude, Gemini, and DeepSeek, across nearly 12,000 real social situations. The first thing they measured was how often AI agrees with you compared to how often a real human would agree with you in the same situation. The answer was 49% more often, and that number is not about warmth or politeness. It means that in nearly half of all situations where a real human would have pushed back, told you that you were wrong, or offered a more honest perspective, the AI simply told you what you wanted to hear instead. Then they pushed harder. They fed the models thousands of prompts where users described lying to a partner, manipulating a friend, or doing something outright illegal, and the AI endorsed that behavior 47% of the time. Not one model out of eleven. Not a specific version of one product. Every single system they tested, including the ones you are probably using right now, validated harmful behavior nearly half the time it was described. The second experiment is the part that should genuinely disturb you. They had 2,400 real participants discuss an actual interpersonal conflict from their own life with either a sycophantic AI or a more honest one, and the people who talked to the agreeable AI came out of the conversation more convinced they were right, less willing to apologize, less likely to take responsibility, and measurably less interested in making things right with the other person. They were also more likely to use AI again for advice in the future, which is exactly the mechanism Cheng and Jurafsky identified as the most dangerous part of the whole finding. The AI is not just telling you what you want to hear. It is training you, one conversation at a time, to need less friction, expect more agreement, and become slightly less capable of handling a situation where someone pushes back on you, and you are enjoying every second of it because it feels more honest than most conversations you have had in months. Jurafsky said it in a single sentence after the paper came out. Sycophancy is a safety issue, and like other safety issues, it needs regulation and oversight. Cheng was more direct about what you should actually do right now. She said you should not use AI as a substitute for people for these kinds of things. That is the best thing to do for now. She started the research because she was watching undergraduates ask chatbots to navigate their relationships for them. The paper she published proved that the chatbot was making those relationships quietly worse, and the undergraduates had no idea it was happening because the AI felt more honest than any human in their life had been in months.
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Eric H Chang retweeted
🎉Congrats to @hightroponin on successfully defending her PhD thesis “Splenic Neuroimmune Mechanisms in the Pathogenesis of Pulmonary Hypertension” this morning at the Elmezzi Graduate School of Molecular Medicine at @NorthwellHealth @StavrosZanos @KeepInRhythm @KatzWomensHlth
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#ddw2026 in Chicago! Lots of interesting results and technology to explore the gut in health and disease.
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Eric H Chang retweeted
I am deeply honored to receive the Cushing Award for Innovation from the @AANSNeuro. For as long as I can remember, I’ve had two dreams: that I might find a way to cure a disease and that I could be a neurosurgeon. These dual hopes started when I was five. That was when my mother died from a glioblastoma. Now, it’s six decades later, and I’ve been extraordinarily fortunate. I was trained by second-generation Cushing-trained neurosurgeon Dr. Russell Patterson. I collaborated with brilliant scientists at some of the world’s best research institutions, including working alongside Sangeeta Chavan and dozens of exceptional colleagues at the Feinstein Institutes at @NorthwellHealth in NY. And in my lab at Feinstein we discovered how the brain controls the immune system via the vagus nerve. We cofounded @Setpointmedical that developed an FDA approved immunoregulating device for neurosurgeons to implant on the vagus. This is a new method to treat treatment resistant rheumatoid arthritis. Our discovery of the vagus nerve inflammatory reflex has put neurosurgery front and center in delivering innovative therapies for autoimmune and inflammatory that I expect will benefit countless millions of patients in the coming years. We can together think back to Harvey Cushing. He celebrated innovation in neurosurgery because it served patients. And of course that is what matters most. Thank you to the @AANSNeuro for this honor and of course for making my dreams come true.
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I'm honored and excited to co-chair the 2026 Bioelectronic Medicine Summit, hosted by the Feinstein Institutes @NorthwellHealth! This September 28-29th, please join us at Chelsea Piers, NYC to hear from an exciting line-up of international speakers in the field. Abstract submissions are open NOW through May 15th, 2026. Hope to see you in New York! bemsummit.org/
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Preliminary Agenda is now online: bemsummit.org/agenda/?events… Conference registration is now live, and we look forward to receiving Abstract submissions to showcase your latest work in bioelectronic medicine. Join us to help shape the future of this field! 🗽🧠💊
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Eric H Chang retweeted
The hill I will die on - we have to rethink graduate training. “Scientists are trained for a world where data speaks for itself. Where misinformation moves slowly. Where scientific expertise naturally rises above noise. That world is gone.” sciencepolitics.org/2026/03/…
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Eric H Chang retweeted
Dear "AI will solve biology" crowd... Our current data in biology is like a pinhead. What we know we don't know is like an Olympic swimming pool. What we don't know we don't know is feasibly the size of a galaxy. This is not an exaggeration; biology is really that complex, and our data is really that lacking against reasonable combinatorial extrapolations of biological complexity.
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Eric H Chang retweeted
1/8 Our preprint is now a peer-reviewed paper :) Big thanks to our reviewers who pushed us to examine our results more carefully and Olivier Wyart (headquarter.paris/) for the exquisite visual. science.org/doi/10.1126/scie…
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Eric H Chang retweeted
Salk Institute scientist Shrek Chalasani has been awarded up to $41.3 million from ARPA-H to advance a breakthrough technology he pioneered, sonogenetics, which uses ultrasound to precisely control cells within the body. This funding will help transform the Chalasani lab’s discovery into a potential noninvasive therapy for a range of conditions, including peripheral neuropathies. By enabling targeted control of mammalian cells without surgery, sonogenetics could redefine how we treat disease. Learn more: salk.edu/news-release/salk-i… #SalkInstitute #ARPAH #Sonogenetics #Neuroscience #BiomedicalInnovation
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Eric H Chang retweeted
Focused Ultrasound in the News! This morning, Rebecca King Crews, wife of actor Terry Crews, revealed her Parkinson’s diagnosis and how focused ultrasound has improved her symptoms. She described reduced tremors and the ability to write with her right hand again for the first time in years. Focused ultrasound was approved by the FDA in 2021 for treating symptoms of Parkinson’s, with expanded approval in 2025 to treat both sides of the brain. Read the full article in @People: bit.ly/47GxA74 Watch the @TODAYShow segment: on.today.com/4vdEhax
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An honor to host 2025 Brain Prize recipient, Dr Frank Winkler, for a talk on cancer neuroscience at the Feinstein Institutes @NorthwellHealth! Amazing data from his lab showing pacemaker-like cells and neural activity in tumor progression. Neuromodulation in oncology loading!! #CancerResearch
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