Funding and incubating replacement research to extend human lifespan. discord.gg/hydradao • $HYDRA 🫀
Joined August 2021
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136 Photos and videos
A new paper from Dowell Bio is out.
Showing us this works in rats is one thing. We are now seeing that spinal cord reattachment in 100kg pigs, a large mammal very similar to humans, is possible.
A major milestone for the HydraDAO-funded spinal repair program. Take a look at the article in Andrei's thread!
Jun 12
A new paper from Dowell Bio!
Recovery after complete spinal cord transection in 100 kg pigs, whose spinal cord anatomy is close to that of humans.
Our first paper in a Q1 journal: PLOS One.
In the photo: a pig posing next to the banner.
Next time, there will be a red carpet.
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HydraDAO retweeted
Jun 13
You can now glue back spinal cords
Brought to you by Dowell Bio, with support from @daohydra
Jun 12
A new paper from Dowell Bio!
Recovery after complete spinal cord transection in 100 kg pigs, whose spinal cord anatomy is close to that of humans.
Our first paper in a Q1 journal: PLOS One.
In the photo: a pig posing next to the banner.
Next time, there will be a red carpet.
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HydraDAO retweeted
Jun 12
This could turn out to be a big milestone...
Jun 12
A new paper from Dowell Bio!
Recovery after complete spinal cord transection in 100 kg pigs, whose spinal cord anatomy is close to that of humans.
Our first paper in a Q1 journal: PLOS One.
In the photo: a pig posing next to the banner.
Next time, there will be a red carpet.
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HydraDAO retweeted
Jun 5
The dark horse of the DeSci ecosystem @daohydra — a longevity DAO doing research into human replacement technologies at the edge of what's fundable. I'm part of the core team, which says everything about the kind of projects my studio gravitates toward.
simaclennan.com/project/hydr…
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HydraDAO retweeted
organ replacement is GOAT... or in this case pig.
this is insane
- 53 yr old clinically dead man becomes first to receive 2 kidneys and a liver from a genetically modified pig
- only a few people have received a single organ transplant..with many clinical trials in the U.S. and China
- transplanting pig kidneys a liver is way more risky/complex
- chinese researchers say it's possible. his organ function was sustained for 5 days, no signs of rejection within 24h
still a long way to go but the progress is incredible. soon organ shortages might become more a manufacturing problem than a matching one. and increasingly a geopolitical priority
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HydraDAO retweeted
May 29
Vladimir Putin is on a $26 billion quest for immortality—and it involves harvesting human organs from tiny pigs on.wsj.com/4a3iVnp
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HydraDAO retweeted
whats easier? repairing organs or replacing them?
A 53-year-old clinically dead man has become the first person to receive two kidneys and a whole liver from a genetically modified pig.
go.nature.com/3QdcO9n
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Sometimes it's their spines and how to reattach them to get crippled mammals walking again
May 24
Most biomedical researchers don't study diseases, they just study mouse biology.🐭
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HydraDAO retweeted
May 19
my talk this year at vitalist bay:
"the slippery slope into deathism"
I discussed how we fell from cosmism to deathism, and every step in between
youtu.be/Jos1Tvsjja8
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HydraDAO retweeted
May 14
Roadmap:
1. Solve aging
2. Solve death
3. Resurrect everyone who didn't make it
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HydraDAO retweeted
The best treatment for aging liver is the new liver. Replacement is a viable long-term therapeutic and longevity strategy. Great insights from the replacement workshop organized by Sierra Lore and team as part of @ARDD_Meeting
onlinelibrary.wiley.com/doi/…
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HydraDAO retweeted
the many camps of longevity
tag yourself
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Everyone is already in a race with the reaper. One rider in that race is replacement.
Not just slowing decline, but outpacing it.
Tissues. Organs. Limbs. Whole bodies.
The future of longevity belongs to those who can replace what time destroys.
Would you bet against your own life?
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DeSci is back in the spotlight. HydraDAO never stopped building.
Building toward spinal cord fusion.
Building toward replacement medicine.
Building toward a future where failed organs, lost limbs, and damaged systems are not the end of the story.
The market can drift. We build anyway.
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DeSci is back. Or... did it never leave?
$CRYO in the last few months:
- Saved space mice from the ISS
- Launched our multi-organ, large animal cryopreservation project
- Continued to make progress on @thecryorat, CryoDB, and many other initiatives
We build; rain or shine.
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HydraDAO retweeted
May 2
How is no one talking about the insane run DeSci coins have been on for weeks now?
Feels like a lot of it is being driven by the broader peptide hype.
Always been a big fan of DeSci, so definitely continuing to watch this space closely.
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Replacement will not be won by printing the right shape and calling it an organ.
Real organs need a blood supply, integration, and innervation to grow, function, and repair.
That is what makes replacement medicine hard.
It is also what makes it real.
The future belongs to organs that work, not printed paste.
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No one has to do this in replacement-based longevity btw
Apr 30
This is her vaginal microbiome report. 100/100 score.
Top 1% of all vaginas.
Her sample is dominated by the single most protective bacterial species a vagina can host (Lactobacillus crispatus).
Only about 25-30% of reproductive age women globally are L. crispatus-dominant, and “dominant” usually means above 50%. Kate is at 98.7%.
The lab found nothing bad to report. (no gardnerella, Candida, STIs, opportunistic pathogens, aerobic vaginitis markers, etc.)
This is linked to lower risk of BV, UTIs, yeast infections, HPV persistence, HSV-2 and HIV acquisition, preterm birth, and improved IVF outcomes.
A vaginal microbiome is downstream of everything: sleep, glucose control, stress, gut health, sexual health, immune function, what you eat, and what you put in it.
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Medicine still struggles to restore what severe injury destroys.
Recent spinal cord injury reviews still describe motor and sensory recovery as poor, with lifelong disability remaining common.
That is exactly why Hydra exists. Not to admire the limits of the body, but to push past them.
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