Venetoclax obinutuzumab combo is approved as front-line tx for pts w #CLL. Can intervening early w this combo vs waiting for symptoms lengthen survival for pts w high-risk (CLL-IPI of 4 ) CLL or small #lymphocytic#lymphoma? @SWOG S1925 trial. SWOG.org/clinical-trials/S19…@NRGonc
Important MURANO tox ax
@anthonymatomd @jeff_sharman et al
28% premature d/c VR<2y
⬇️ PFS in prem d/c ven for any reason (PD excluded;p<0.0001) due to AE
Interrupt for AE 69% / dose ⬇️ 23% both no impact on PFS/OS
Tox mx continued Rx important for VenR PFS outcome #CLL#lymsm
There may not have been an official ASH run this year, but anyone else still get in their #FauciFour ? If daily running is the secret to Dr Fauci leading the nation through this chaos, may I never stop.
Also, the San Diego skyline has nothing on my view.
#IRunForASH
Flashback Friday and my upcoming first Twitter-versary.
This tweet from an amazing #cll leader, along with a little help from @chadinabhan and @anthonymatomd finally got me on board. Looking forward to #ash20 highlights and my first ash on Twitter.
To teach is to learn, twice
And thankful for this opportunity from #ASH20, twice -
to learn from so many others but also to work on this with an amazing fellow @DukeFellows, Dr Ashley Hanlon @amilliga, that has taught me so much and co authored this chapter #dukefamily
We are so excited to welcome @_joycehwang@andrewpeseski@FahminB_MDPhD Drs. Kathrine DiNardo, Cameron Oswalt, Grayce Selig, and Cameron Wood to the Duke Heme/Onc Fellowship Program! We are so excited to have you join our wards and clinics in July 2021! @DukeCancer@dukemedicine
Intolerance is a failure of the medication for that given patient, patients don’t fail therapy.
Grateful to be a part of this collaborative effort @DukeHMCT and for all trials aimed at the unmet need of intolerance. @anthonymatomd @AndreaSitlinger and many others
every point exactly, @JasAWebb - easy to feel defeated hearing this news, but will take that energy and use it to inspire action towards the many challenges that face us...