Genetically-encoded discovery are the heart of Derda Lab. A diverse and dynamic group located at UAlberta working on #phage #peptides & #glycans

Joined April 2019
58 Photos and videos
Derda Lab retweeted
To distract everyone from the devastating NIH news, I recommend reading this Mirror Image Life discussion in Science magazine science.org/doi/10.1126/scie… or popular press cbc.ca/radio/thecurrent/scie… and our view on this topic: TLDR: do not forget about Glycans! biorxiv.org/content/10.1101/…
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Derda Lab retweeted
The liquid lectin array detects compositional glycocalyx differences using multivalent DNA-encoded lectins on phage by Guilherme Meira Lima, @RatmirDerda @derda_lab, et al. at @UAlberta @StanfordUChem @usponline dlvr.it/TGL3vq

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Derda Lab retweeted
Excited to share our latest work on DNA-encoded liquid lectin array! This work would not have been possible without the amazing support and contributions of my colleagues at the University of Alberta!
Replying to @CellChemBiol
@CellChemBiol publication of Liquid Lectin Array (LiLA) led by Guilherme Meira Lima (scholar.google.com/citations…) PhD Student from @derda_lab and co-authors from @MatthewMacaule4 Lab, @glycocode (Lara Mahal), Raymond Lai et al, now in cell.com/cell-chemical-biolo…
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Derda Lab retweeted
Online now! The liquid lectin array detects compositional glycocalyx differences using multivalent DNA-encoded lectins on phage by Guilherme Meira Lima, @RatmirDerda @derda_lab, et al. at @UAlberta @StanfordUChem @usponline dlvr.it/TFkMqZ #chembiol

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Derda Lab retweeted
24 Oct 2024
Congrats to all the GlycoNet researchers on their paper about the liquid lectin array (LiLA), which uses DNA-encoded #lectins to detect subtle glycocalyx differences and enhance our understanding of #glycan composition. @derda_lab @MatthewMacaule4 @glycocode @miratsojitra
Replying to @CellChemBiol
@CellChemBiol publication of Liquid Lectin Array (LiLA) led by Guilherme Meira Lima (scholar.google.com/citations…) PhD Student from @derda_lab and co-authors from @MatthewMacaule4 Lab, @glycocode (Lara Mahal), Raymond Lai et al, now in cell.com/cell-chemical-biolo…
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Derda Lab retweeted
Replying to @CellChemBiol
@CellChemBiol publication of Liquid Lectin Array (LiLA) led by Guilherme Meira Lima (scholar.google.com/citations…) PhD Student from @derda_lab and co-authors from @MatthewMacaule4 Lab, @glycocode (Lara Mahal), Raymond Lai et al, now in cell.com/cell-chemical-biolo…
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Derda Lab retweeted
The Liquid Lectin Array (LiLA) paper is out in @CellChemBiol. Congratulations to @Guilher63551077 for this amazing publication and it was my privilege to play a [small] part in this project. #Siglec #Glycotime #Phage #Glycans cell.com/cell-chemical-biolo…
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Derda Lab retweeted
#FeaturedProtocol this week: #Liquidglycanarray (LiGA) platform to profile #glycan-lectin interactions on the surface of live cells bit.ly/4hjtZyE #Glycotime #Siglec

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Derda Lab retweeted
17 Oct 2024
Congrats to the GlycoNet team on this important research that advances our understanding of how glycans interact with proteins on live cells using the LiGA platform! @miratsojitra @RatmirDerda @MatthewMacaule4 @ednschmidt @Guilher63551077
Excited to report that protocol for DNA-encoded, Liquid Glycan Array (LiGA) is out in @NatureProtocols. In addition to the protocol, we report how the expression level of Siglecs and cell types affect their ability to bind to LiGA. nature.com/articles/s41596-0…
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Derda Lab retweeted
A big thank you to @RatmirDerda and @MatthewMacaule4 for their mentorship! This wouldn't have reached the finish line without a lot of help from @Guilher63551077 @ednschmidt, Kelli (Macauley lab) and all past and presents members of @derda_lab
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Derda Lab retweeted
DNA-encoded, Liquid Glycan Array (LiGA) and its application to cell-surface profiling is out in @NatureProtocols . Big thanks to @miratsojitra for leading the effort and @MatthewMacaule4 members of Macaluley Lab and @derda_lab ! rdcu.be/dXaNJ

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Derda Lab retweeted
I'm curious about any feedback from #Glycobiology #glycan #carbohydrate #glycotime community on @derda_lab preprint on DNA-encoded liquid #lectin arrays (LiLA). [LiLA] non-lineary amplifies detection of compositional differences of the cellular #glycocalyx biorxiv.org/content/10.1101/…
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6 Oct 2023
Delighted to share the pre-print of a LiGA protocol with detailed instructions to profile the glycan binding preference of cell surface #Siglecs using #ngs #glycotime Shout out to @miratsojitra @ednschmidt @Guilher63551077 @MatthewMacaule4 @RatmirDerda biorxiv.org/content/10.1101/…
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6 Oct 2023
This protocol follows previous publication from our lab describing ways to synthesize LiGA using synthetic glycans (doi.org/10.1038/s41589-021-0…) or direct chemoenzymatic synthesis of N-glycans on phage (doi.org/10.1038/s41467-023-4…) Check it out!

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28 Aug 2023
Exciting news from @tracy6528! 🎉 Check out her latest paper on 'Chemoenzymatic synthesis of genetically-encoded multivalent liquid N-glycan arrays' available online now. 📚🔬 nature.com/articles/s41467-0…

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Derda Lab retweeted
28 Jul 2023
Congratulations to our friend @miratsojitra who is now officially Dr. Sojitra. We are so proud of you. People will talk about how great you are as a scientist but we (Ann and me) will always remember you as our great friend.
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Derda Lab retweeted
Here we show that peptide-glycan chimera can be made on the same instrument on solid support. Next, an instrument to make #glycopeptides for #glycotime studies will be revealed.
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18 May 2023
Today is the last day of our intern Allison. It's so nice to have you in our group for the past 4 months. All the best to your future adventures!
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Derda Lab retweeted
Really proud to have worked with this guy and to have watched him grow both as a scientist and as a human being over his undergrad career. Congrats, @ryannqiu! :)
5 May 2023
Congratulations to our superstar undergrad @ryannqiu for winning the best oral presentation award at the #wcucc2023!!! Very well deserved for all his hard work and dedication.
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5 May 2023
Congratulations to our superstar undergrad @ryannqiu for winning the best oral presentation award at the #wcucc2023!!! Very well deserved for all his hard work and dedication.
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