Excited to share our latest work on DNA-encoded liquid lectin array! This work would not have been possible without the amazing support and contributions of my colleagues at the University of Alberta!
Congrats to all the GlycoNet researchers on their paper about the liquid lectin array (LiLA), which uses DNA-encoded #lectins to detect subtle glycocalyx differences and enhance our understanding of #glycan composition.
@derda_lab @MatthewMacaule4 @glycocode @miratsojitra
Congrats to the GlycoNet team on this important research that advances our understanding of how glycans interact with proteins on live cells using the LiGA platform!
@miratsojitra@RatmirDerda @MatthewMacaule4 @ednschmidt@Guilher63551077
Excited to report that protocol for DNA-encoded, Liquid Glycan Array (LiGA) is out in @NatureProtocols. In addition to the protocol, we report how the expression level of Siglecs and cell types affect their ability to bind to LiGA.
nature.com/articles/s41596-0…
A big thank you to @RatmirDerda and @MatthewMacaule4 for their mentorship! This wouldn't have reached the finish line without a lot of help from @Guilher63551077@ednschmidt, Kelli (Macauley lab) and all past and presents members of @derda_lab
DNA-encoded, Liquid Glycan Array (LiGA) and its application to cell-surface profiling is out in @NatureProtocols . Big thanks to @miratsojitra for leading the effort and @MatthewMacaule4 members of Macaluley Lab and @derda_lab ! rdcu.be/dXaNJ
This protocol follows previous publication from our lab describing ways to synthesize LiGA using synthetic glycans (doi.org/10.1038/s41589-021-0…) or direct chemoenzymatic synthesis of N-glycans on phage (doi.org/10.1038/s41467-023-4…)
Check it out!
Exciting news from @tracy6528! 🎉 Check out her latest paper on 'Chemoenzymatic synthesis of genetically-encoded multivalent liquid N-glycan arrays' available online now. 📚🔬 nature.com/articles/s41467-0…
Congratulations to our friend @miratsojitra who is now officially Dr. Sojitra. We are so proud of you. People will talk about how great you are as a scientist but we (Ann and me) will always remember you as our great friend.
Here we show that peptide-glycan chimera can be made on the same instrument on solid support. Next, an instrument to make #glycopeptides for #glycotime studies will be revealed.
Really proud to have worked with this guy and to have watched him grow both as a scientist and as a human being over his undergrad career. Congrats, @ryannqiu! :)
Congratulations to our superstar undergrad @ryannqiu for winning the best oral presentation award at the #wcucc2023!!! Very well deserved for all his hard work and dedication.
Congratulations to our superstar undergrad @ryannqiu for winning the best oral presentation award at the #wcucc2023!!! Very well deserved for all his hard work and dedication.