Premenopausal women with ACS are often labeled “low risk.” The reality: rising MI rates, more delays and misdiagnoses, and worse outcomes vs men.
ACS in younger women is different and needs tailored care, earlier recognition, and equity in treatment.
ahajournals.org/doi/10.1161/…
ALT Screening
• Use validated instruments to screen for depression and anxiety (eg, BDI-II, PHQ-9, GDS, HADS)
• Optimal timing of screening is uncertain but could be conducted at intervals post-ACS
• Consider referral to mental health care professional
Diagnosis
• Confirm diagnosis of depression or anxiety, or both, prior to initiating treatment
Treatment
• Use shared decision-making to inform treatment decision
• CBT and antidepressant mediations (eg, SSRI) are options and may be used together for optimal effect
Re-Assessment
• Reassess depression or anxiety, or both,
symptoms and necessity of continued treatment or modification to treatment plan
CHAMPION trial results. Watchman met noninferiority compared to DOAC for CV death, stroke and systemic embolization. And reduced the primary safety endpoint of non-procedural bleeding.
🔓 For a limited time until January 31, we are offering free promotional access to this new article in #CJC! 🌐
Intravenous thrombolysis in SCAD: insights from the Canadian SCAD Study ⬇️
onlinecjc.ca/article/S0828-2…@vanscad@docsaw@CardioUBC
Is SCAD genetic?"
It is the single most common question I get from patients in clinic.
For years, the answer was a frustrating "maybe."
But we are finally moving from "bad luck" to biological mechanisms.
Let's talk about the ADAMTSL4 connection and arterial fragility. 🧬🫀
#SCAD
In another analysis, we found a significant burden of rare variants in FMD-associated genes (e.g., F11R, TLN1) in SCAD patients compared to controls.
Key takeaway: SCAD is rarely "monogenic" but heavily influenced by a cumulative burden of rare variants.
google.com/search?q=jamanetw…
To date there has been no attempt to develop integrated management pathways for the diagnosis and management of premenopausal women presenting with ACS.
This statement discusses key considerations for invasive angiography, revascularization, and related procedures such as arterial access, intravascular imaging, left ventricular angiography, invasive physiology, and provocative testing.
✍🏼 @docsaw@EstherSHKimMD@JohnBlakeman_RN@hollandtamis@MonSangh@MirvatAlasnag
📷 Diagnosis and management of ACS in premenopausal women.
Try out the new SCAD Expert chatbot that I created for scadnavigator.com
AI tools are amazing. This should be a really good educational resource on SCAD for patients and clinicians!
Make sure you don't miss #CSILAA2025, a leading conference on stroke prevention atrial fibrillation!
What makes CSI Focus LAA special?
Well, there are a couple of reasons:
🎤 The interactive sessions allow you to have your opinions heard and questions answered
☕ Learn and have a discussion about intriguing and challenging real-world cases in the informal, yet proven format of our popular Cathlab café
🫀 Receive valuable hands-on experience in our new CSI 360° training
📹Live cases from renowned centers give you the opportunity to learn from the best operators
🤝 Participate in discussions and network with faculty and colleagues from all over the world.
And last but not least, CSI Focus LAA will be held in conjunction with CSI Focus D-HF, the leading conference in the field of device-based heart failure therapy.
Feel the synergy at the joint session: heart failure and AF!
Two leading cardiology meetings, one venue 💓🫀
Register for CSI Focus D-HF or CSI Focus LAA — and benefit from both conferences happening side by side in Frankfurt, Dec 5-6 2025!
Special highlight: Joint session: heart failure and AF