New Publishing House founders are out. Excited to be working with @drpatel 💣

I'm lucky enough to have a great doctor and access to excellent Bay Area medical care. I've taken lots of standard screening tests over the years and have tried lots of "health tech" devices and tools. With all this said, by far the most useful preventative medical advice that I've ever received has come from unleashing coding agents on my genome, having them investigate my specific mutations, and having them recommend specific follow-on tests and treatments. Population averages are population averages, but we ourselves are not averages. For example, it turns out that I probably have a 30x(!) higher-than-average predisposition to melanoma. Fortunately, there are both specific supplements that help counteract the particular mutations I have, and of course I can significantly dial up my screening frequency. So, this is very useful to know. I don't know exactly how much the analysis cost, but probably less than $100. Sequencing my genome cost a few hundred dollars. (One often sees papers and articles claiming that models aren't very good at medical reasoning. These analyses are usually based on employing several-year-old models, which is a kind of ludicrous malpractice. It is true that you still have to carefully monitor the agents' reasoning, and they do on occasion jump to conclusions or skip steps, requiring some nudging and re-steering. But, overall, they are almost literally infinitely better for this kind of work than what one can otherwise obtain today.) There are still lots of questions about how this will diffuse and get adopted, but it seems very clear that medical practice is about to improve enormously. Exciting times!

C. S. Lewis on why kids need to read

Terry Tao is the ultimate shape rotator

Some journalists seem alarmed that Elon has so much influence over Trump, but this is actually good news. Someone would have Trump's ear if Elon didn't, and it would surely be someone less smart and more politically extreme. Remember Steve Bannon?

Cigarette sales and lung cancer deaths are the same curve, shifted 25 years.

Apple and Google are reportedly in talks to integrate Gemini into the iPhone. The tech giants teaming up to take on OpenAI/Microsoft could be a massive move. The advanced AI capabilities could be coming to billions of iPhone users as soon as iOS 18 this year.

via @NYTimes nytimes.com/2023/07/10/upsho…

An estimated 1.8 million reservations, more hype than any vehicle in years, it's built ground up from first principles, and most truck buyers are lifestyle buyers. It ain't gonna flop.

Thanks @madhuridixit for introducing me to my very first Vada Pav — it was delicious!

Family of 14y/o who was assaulted at a Coppell Middle school has hired an attorney. They started an online petition with more than 300,000 signatures. Their statement below: #justiceforshaan @wfaa Link to story: wfaa.com/article/news/local/…

BREAKING: Supreme Court Justice Sonia Sotomayor DENIES request by New York City school teachers to block city’s vaccine mandate

Anyone donating >$1k USD to donate.indiacovidresources.i… I will give 1 hour of US medical school admissions/college admissions advise and help with application etc. YC founder, US doctor and medical school advisor. DM me receipt.

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